Abstract：
:Heart failure is the main cause of poor outcome following open heart surgery and experimental studies have demonstrated that glucose-insulin-potassium (GIK) infusion exerts cardioprotective effects by reducing myocardial ischemia-reperfusion injuries. This randomized controlled trial was designed to assess the effects of GIK on left ventricular function in moderate-to-high risk patients undergoing on-pump isolated coronary artery bypass surgery (CABGS), or combined with aortic valve replacement. The primary outcomes were the effects of GIK on two- and three-dimensional left ventricular ejection fraction (2D and 3D-LVEF), and on transmitral flow propagation velocity (Vp), that occurred between the pre- and post-CPB periods. GIK administration was associated with favorable interaction effects (p < 0.001) on 2D-LVEF, 3D-LVEF and Vp changes over the study periods. In GIK pretreated patients (N = 54), 2-D and 3D-LVEF and Vp increased slightly during surgery (mean difference [MD] + 3.5%, 95% confidence interval [95% CI] - 0.2 to 7.1%, MD + 4.0%, 95% CI 0.6-7.4%, and MD + 22.2%, 95% CI 16.0-28.4%, respectively). In contrast, in the Placebo group (N = 46), 2D-and 3D-LVEF, as well as Vp all decreased after CPB (MD - 7.5% [- 11.6 to - 3.4%], MD - 12.0% [- 15.2 to - 8.8%] and MD - 21.3% [- 25.7 to - 16.9%], respectively). In conclusion, the administration of GIK resulted in better preservation of systolic and diastolic ventricular function in the early period following weaning from CPB.
journal_name
J Clin Monit Computjournal_title
Journal of clinical monitoring and computingauthors
Licker M,Reynaud T,Garofano N,Sologashvili T,Diaper J,Ellenberger Cdoi
10.1007/s10877-019-00280-5subject
Has Abstractpub_date
2020-02-01 00:00:00pages
29-40issue
1eissn
1387-1307issn
1573-2614pii
10.1007/s10877-019-00280-5journal_volume
34pub_type
杂志文章abstract：:Recently a novel pain recognition indicator derived from electroencephalogram(EEG) signals, pain threshold index(PTI) has been developed. The aim of this study was to determine whether PTI can be used for prediction of postoperative acute pain while surgical pleth index(SPI) applied as control. Eighty patients undergo...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-020-00604-w
更新日期：2020-10-12 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10877-017-0074-3
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:Various studies worldwide have found that sound levels in hospitals significantly exceed the World Health Organization (WHO) guidelines, and that this noise is associated with audible signals from various medical devices. The pulse oximeter is now widely used in health care; however the health effects associa...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-008-9125-0
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abstract：:Bioreactance is a novel non-invasive method for cardiac output measurement that involves the analysis of blood flow-dependent changes in the phase shifts of electrical currents applied across the chest. The present study (1) compared resting and exercise cardiac outputs determined by bioreactance and bioimpedance meth...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-012-9334-4
更新日期：2012-04-01 00:00:00
abstract：:Near-infrared spectrophotometry assesses cerebral oxygen saturation (ScO2) based on the absorption spectra of oxygenated and deoxygenated hemoglobin, and the translucency of biological tissue, in the near-infrared band. There is increasing evidence that optimising cerebral oxygenation, guided by ScO2, is associated wi...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-014-9642-y
更新日期：2015-10-01 00:00:00
abstract：:Perioperative goal-directed therapy is considered to improve patient outcomes after high-risk surgery. The association of compliance with perioperative goal-directed therapy protocols and postoperative outcomes is unclear. The purpose of this study is to determine the effect of protocol compliance on postoperative out...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-020-00585-w
更新日期：2020-09-12 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-020-00567-y
更新日期：2020-07-31 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-019-00328-6
更新日期：2020-04-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,评审
doi：10.1007/s10877-020-00534-7
更新日期：2020-05-26 00:00:00
abstract：:Total shoulder arthroplasty (TSA) is typically performed in the beach-chair position. Maintenance of adequate mean arterial pressure is required to provide appropriate cerebral perfusion pressure and prevent cerebral ischemia. Placement of an arterial line to facilitate invasive monitoring is discretionary, based on c...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-016-9939-0
更新日期：2017-10-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-008-9135-y
更新日期：2008-08-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-015-9747-y
更新日期：2016-10-01 00:00:00
abstract：:FloTrac/Vigileo™ system is based on arterial pressure waveform analysis arterial pressure-based CO (APCO). Therefore, systemic vascular resistance (SVR) can influence the accuracy of APCO. The purpose of this study is to evaluate the relationship between SVR and the accuracy of APCO. We managed 50 consecutive patients...
journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-013-9481-2
更新日期：2013-12-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1015426015547
更新日期：2002-01-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-019-00390-0
更新日期：2020-10-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10877-019-00308-w
更新日期：2019-10-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-017-0033-z
更新日期：2018-06-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1016362209175
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pub_type： 杂志文章
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journal_title：Journal of clinical monitoring and computing
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journal_title：Journal of clinical monitoring and computing
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章,随机对照试验
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更新日期：2019-10-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1023/a:1009914019889
更新日期：1999-01-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-005-0879-3
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-017-0088-x
更新日期：2018-10-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 信件
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
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更新日期：2016-10-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-005-9005-9
更新日期：2006-04-01 00:00:00
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journal_title：Journal of clinical monitoring and computing
pub_type： 杂志文章
doi：10.1007/s10877-020-00584-x
更新日期：2020-09-29 00:00:00
