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Overweight and obese cardiac patients have better prognosis despite reporting worse perceived health and more conventional risk factors.

Abstract：

OBJECTIVE:The obesity paradox in patients with cardiovascular disease (CVD) remains unexplained. We examined the role of self-rated health, behavioral and objectively assessed risk factors, in order to further explore mechanisms that might influence the association between body mass index (BMI) and mortality in CVD patients. METHODS:Participants were 4417 community dwelling adults from the Health Survey for England and Scottish Health Survey from 1994-2004 (aged 65.9 ±[Standard deviation (SD) 10.6 yrs], 56.2% men) with clinically diagnosed CVD at baseline. RESULTS:There were 570 CVD and 1441 and all-cause deaths, over an average of 7.3 yrs of follow-up. Overweight and obese patients reported worse self-rated health, more co-morbidities and biological risk factors. However, compared with non-obese participants (BMI<25 kg/m(2)), a lower risk of all-cause mortality was observed in overweight (BMI 25<30 kg/m(2)) (Hazard ratio [HR]=0.73, 95% confidence intervals [CI], 0.64-0.82), and obese (BMI ≥ 30 kg/m(2)) participants (HR=0.84, 95% CI, 0.73-0.97) after adjustment for age, sex, smoking, physical activity, and various co-morbidities. CONCLUSIONS:Overweight and obese CVD patients have better prognosis despite reporting worse health, more co-morbidities and risk factors, and poorer adherence to lifestyle advice.

journal_name

Prev Med

journal_title

Preventive medicine

authors

Hamer M,Stamatakis E

doi

10.1016/j.ypmed.2013.02.012

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

12-6

issue

1

eissn

0091-7435

issn

1096-0260

pii

S0091-7435(13)00057-1

journal_volume

57

pub_type

杂志文章

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