Abstract:
BACKGROUND:This study aims at identifying determinants of all-cause mortality in elderly populations of different countries. METHODS:Men ages 65-84 years from defined administrative areas were enrolled in Finland (rural areas of east and west Finland; N = 693), in the Netherlands (the town of Zutphen; N = 851), and in Italy (the rural areas of Crevalcore and Montegiorgio; N = 682). They were survivors of cohorts studies for 25 years within the Seven Countries Study with the addition of a subgroup of the same ages in the Netherlands. RESULTS:Five-year death rates from all causes were higher in Finland (297 per 1000), intermediate in the Netherlands (231 per 1000), and lower in Italy (191 per 1000). Five-year all-cause mortality was studied in relation to measurements taken at entry (age, systolic and diastolic blood pressure, non-high-density lipoprotein (HDL) and HDL cholesterol, body mass index, heart rate, smoking habits, and presence of coronary heart disease manifestations). Univariate and multivariate analyses were performed (in the latter models, both linear and quadratic terms were used for most variables) with all-cause mortality as endpoint. Results suggested significant predictive power of age (direct relationship) and, in most cases, U-shaped relationships of risk factors to mortality. Non-HDL cholesterol showed significant relationships with mortality in Finland and the Netherlands, HDL cholesterol in all three countries, systolic blood pressure only in Finland, body mass index in Finland and the Netherlands, smoking habits only in Finland, and heart rate in none. Levels of risk factors associated with the lowest death rate in the pool of all countries were 183.3 mg/dl for non-HDL cholesterol, 59.8 for HDL cholesterol, 177.5 mm Hg for blood pressure, and 30.2 kg/m square for body mass index. CONCLUSIONS:In these elderly men the association of traditional risk factors with all-cause mortality is reduced, U-shaped, or even inverted. This is probably due to selection due to previous mortality, to comorbidity, and to changes in homeostatic mechanisms.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Menotti A,Kromhout D,Nissinen A,Giampaoli S,Seccareccia F,Feskens E,Pekkanen J,Tervahauta Mdoi
10.1006/pmed.1996.0062subject
Has Abstractpub_date
1996-05-01 00:00:00pages
319-26issue
3eissn
0091-7435issn
1096-0260pii
S0091743596900626journal_volume
25pub_type
杂志文章abstract:OBJECTIVE:The sodium intake of participants of the Healthy Aging in Neighborhoods of Diversity across the Life Span study who were in three of the special population groups identified by the Dietary Guidelines for Americans, 2010 (those with hypertension, African Americans, and those ≥51years) was analyzed to determine...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2013.06.006
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:To identify factors associated with age of smoking initiation and distinguish vulnerable periods for initiation according to those factors. METHOD:Discrete time hazards analysis was used to model smoking initiation as a function of age (5-23), demographic and familial influence variables (measured at age 13)...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2006.09.004
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Obesity is associated with several chronic conditions, increased medical costs, and premature death. Proper assessment of changes in body weight is crucial to control the spread of obesity. We used data from the Behavioral Risk Factor Surveillance System to explore how adults in the United States recall their...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.04.019
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:There has been an increasing realization of the need for environmental interventions to increase physical activity levels in the population. Although promising, the impact of these strategies in reducing obesity-related disparities will be limited by the presence of inequities in the distribution of activity-...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2009.07.016
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:As part of a 3-year demonstration project to improve pneumococcal polysaccharide vaccine (PPV) coverage among older adults, the Minnesota Department of Health conducted a baseline evaluation of knowledge, attitudes, and beliefs among the general public regarding PPV. METHODS:A random-digit dialing telephone...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2001.0839
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Despite the cost-effectiveness of physician smoking cessation counseling, many physicians do not adhere to current clinical practice guidelines. METHODS:A cross-sectional mail survey was conducted in a random sample of general practitioners in Montreal to document cessation-counseling practices and identify...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2001.0937
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVE:Existing data suggest that influenza vaccination rates among adults in the United States fall far short of the Healthy People 2010 goals and the updated Healthy People 2020 targets. We identified characteristics associated with influenza vaccination that might inform strategies for increasing coverage. METHO...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.03.008
更新日期:2012-05-01 00:00:00
abstract::In Italy, the cohorts of women who were offered Human papillomavirus (HPV) vaccination in 2007/08 will reach the age (25years) for cervical cancer (CC) screening from 2017. The simultaneous shift from cytology-based screening to HPV test-based screening gives the opportunity for unprecedented reorganisation of CC prev...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.11.020
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Blood pressure (BP) reduction is crucial in reducing cardiovascular (CV) morbidity and mortality in the community. Subjects aged 20-65 seldom visit the primary care clinics, so they are unlikely to be detected without an active outreach screening program. The aim of the project was to prepare a professional ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2003.09.003
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Whereas self-efficacy expectations have been identified as important determinants of exercise participation patterns, little empirical work that examines efficacy expectations as outcomes of exercise participation or their theoretical relationship to other psychological outcomes associated with exercise has ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1995.1053
更新日期:1995-07-01 00:00:00
abstract::This study identified barriers and facilitators of repeat participation in mammography and breast physical examination among women ages 50 years and over. Telephone interviews were conducted with 910 women in this age group. Forty percent of respondents had never had a mammogram. Only 38% had had one in the past 12 mo...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(90)90028-i
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVES:Determine among a representative sample of pediatricians (Peds), family medicine (FM), and general internal medicine (GIM) physicians in the 2009-2010 influenza season physicians': 1) practices and experiences with delivery of seasonal and pH1N1 influenza vaccines; and 2) anticipated and experienced barriers...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.04.014
更新日期:2012-07-01 00:00:00
abstract::High-risk human papillomavirus (hrHPV) assessment as a primary screening test improves sensitivity but decreases specificity. Determining risk for cervical abnormalities and adapting policy accordingly may improve the balance between screening benefits and harms. Our aim is to assess the value of factors other than HP...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2019.105927
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The differences of urokinase-type plasminogen activator (u-PA) and tissue-type plasminogen activator (t-PA) between maximal treadmill and deep-water running have not been reported. The purpose of this investigation was to compare u-PA and t-PA levels during maximal treadmill and deep-water running. METHODS:...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.ypmed.2004.01.021
更新日期:2004-07-01 00:00:00
abstract::This paper argues that substantive and sustainable population-wide improvements in physical activity can be achieved only through the large scale adoption and implementation of policies and practices that make being active the default choice and remaining inactive difficult. Meta-volition refers to the volition and co...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2009.09.004
更新日期:2009-10-01 00:00:00
abstract::Men who have sex with men and women (MSMW) compose a subset of men who have sex with men (MSM) and represent an estimated 35% of MSM. Research on the HIV risk behaviors of MSMW has largely focused on their behaviors in comparison to men who have sex with men only (MSMO). Results suggest that compared to MSMO, MSMW are...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.04.024
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:Habitual short sleep duration is a common practice linked to weight gain and risk of obesity. Our objective was to examine the association between sleep duration with other behaviors, such as physical activity and nutrition, which are important for obesity prevention efforts. METHODS:We used cross-sectional ...
journal_title:Preventive medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ypmed.2007.11.008
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:This study tested the effects of two organizational support processes, the provision of financial incentives for superior clinical performance and the availability of a patient (smoker) registry and proactive telephone support system for smoking cessation, on provider adherence to accepted practice guideline...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0091-7435(02)00052-x
更新日期:2003-03-01 00:00:00
abstract::In the Amsterdam Growth and Health Longitudinal Study (AGAHLS) biological risk factors for chronic diseases were measured on eight separate occasions over a period of 20 years in a group of apparently healthy males and females (n = 164). Data were first collected from participants at 13 years of age. At each of the ei...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2002.1107
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Identification of risk factors for adverse pregnancy outcome is a main component of preconception care, but requires adequate time and knowledge. This study compares self-administered questionnaires to history taking by a physician to evaluate the reliability of such a screening tool for prepregnancy risk de...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2002.1009
更新日期:2002-05-01 00:00:00
abstract::Curiosity is a potential risk factor for electronic cigarette (e-cigarette) use, which has increased considerably among US youth in recent years. We examined the relationship between curiosity about e-cigarettes and perceived harm, comparative addictiveness, and e-cigarette advertisement exposure. Data came from the 2...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.05.001
更新日期:2016-08-01 00:00:00
abstract::Current treatment for depression is not considered effective among all cases and, thus far, nutritional protocols are minimal within depression treatment guidelines. Recently, there has been increasing interest in a possible protective and modifiable role of diet in common mental disorders, including depression, due t...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.03.016
更新日期:2017-06-01 00:00:00
abstract::Using X-ray fluorescence spectrometry, 11 heavy elements at concentrations that are easily detectable have been identified in smokeless tobacco products. These concentrations were found to increase in cheek epithelium samples of the user after exposure to smokeless tobacco. This feasibility study suggests that the lev...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(88)90048-5
更新日期:1988-07-01 00:00:00
abstract:OBJECTIVE:To examine whether total physical activity or activity patterns are associated with metabolic syndrome and its components. METHODS:Participants include 1994 controls from a case-control study of non-fatal myocardial infarction in Costa Rica (1994-2004). Physical activity was assessed via self-administered qu...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2014.11.006
更新日期:2015-01-01 00:00:00
abstract::We aimed to assess the effectiveness of 'Paesaggi di Prevenzione', a school-based prevention program delivered by trained teachers and designed to tackle smoking, alcohol misuse, dietary risks, and physical inactivity in adolescence. We evaluated the program between 2010 and 2013 with a two-arm, parallel-group, multic...
journal_title:Preventive medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ypmed.2019.04.001
更新日期:2019-07-01 00:00:00
abstract::Social inequities compromise health-related quality of life (HR-QoL) among women living with HIV (WLWH). Little is known about health impacts of intersecting stigma based on HIV status, race and gender among WLWH or potential mechanisms to promote HR-QoL. We tested pathways from multiple types of stigma (HIV-related, ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.12.018
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:From a preventive point of view, it is especially important to investigate the life style risk factors connected to cardiovascular disease (CVD) biological risk factors clustering. The purposes of this study were (I) to determine in pediatric population the coexistence of biological cardiovascular disease ri...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2004.02.023
更新日期:2004-09-01 00:00:00
abstract::Features of the physical environment have an impact on the human behaviour. Thus, planners and policymakers around the world should aim at providing environments that are perceived as being of good quality, in which the residents enjoy spending time and moving around in. It is widely acknowledged that urban environmen...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.11.015
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To assess the association between socioeconomic status (SES) and inflammatory markers using two different European population samples. METHODS:We used data from the CoLaus (N=6412, Lausanne, Switzerland) and EPIPorto (N=1205, Porto, Portugal) studies. Education and occupational position were used as indicato...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2014.11.031
更新日期:2015-02-01 00:00:00
abstract::The presence of risk factors for cardiovascular diseases were investigated in 7- and 11-year-old schoolchildren (808 subjects). Data analysis was performed according to sex, age, and country of origin of the father. The following variables were investigated: weight, height, total plasma cholesterol (TCH), high density...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(83)90250-5
更新日期:1983-05-01 00:00:00