Serial testing from a 3-day collection period by use of the Bartonella Alphaproteobacteria growth medium platform may enhance the sensitivity of Bartonella species detection in bacteremic human patients.

Abstract:

:Patients with infection from bacteremic Bartonella spp., tested using Bartonella Alphaproteobacteria growth medium (BAPGM), were retrospectively categorized into one of two groups that included those whose blood was collected once (group 1; n = 55) or three times (group 2; n = 36) within a 1-week period. Overall, 19 patients (20.8%) were PCR positive for one or more Bartonella spp. using the BAPGM platform. Seven patients (12.7%) in group 1 tested positive, and 12 patients (33.3%) in group 2 tested positive. Detection was improved when the patients were tested three times within a 1-week period (odds ratio, 3.4 [95% confidence interval, 1.2 to 9.8]; P = 0.02). Obtaining three sequential blood samples during a 1-week period should be considered a diagnostic approach when bartonellosis is suspected.

journal_name

J Clin Microbiol

authors

Pultorak EL,Maggi RG,Mascarelli PE,Breitschwerdt EB

doi

10.1128/JCM.00123-13

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

1673-7

issue

6

eissn

0095-1137

issn

1098-660X

pii

JCM.00123-13

journal_volume

51

pub_type

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