Genome-based estimates of fungal rDNA copy number variation across phylogenetic scales and ecological lifestyles.

Abstract:

:Ribosomal DNA (rDNA) copy number variation (CNV) has major physiological implications for all organisms, but how it varies for fungi, an ecologically ubiquitous and important group of microorganisms, has yet to be systemically investigated. Here, we examine rDNA CNV using an in silico read depth approach for 91 fungal taxa with sequenced genomes and assess copy number conservation across phylogenetic scales and ecological lifestyles. rDNA copy number varied considerably across fungi, ranging from an estimated 14 to 1,442 copies (mean = 113, median = 82), and copy number similarity was inversely correlated with phylogenetic distance. No correlations were found between rDNA CNV and fungal trophic mode, ecological guild or genome size. Taken together, these results show that like other microorganisms, fungi exhibit substantial variation in rDNA copy number, which is linked to their phylogeny in a scale-dependent manner.

journal_name

Mol Ecol

journal_title

Molecular ecology

authors

Lofgren LA,Uehling JK,Branco S,Bruns TD,Martin F,Kennedy PG

doi

10.1111/mec.14995

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

721-730

issue

4

eissn

0962-1083

issn

1365-294X

journal_volume

28

pub_type

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