Effect of heat shock, pretreatment and hsp70 copy number on wing development in Drosophila melanogaster.


:Naturally occurring heat shock (HS) during pupation induces abnormal wing development in Drosophila; we examined factors affecting the severity of this induction. The proportion of HS-surviving adults with abnormal wings varied with HS duration and intensity, and with the pupal age or stage at HS administration. Pretreatment (PT), mild hyperthermia delivered before HS, usually protected development against HS. Gradual heating resembling natural thermal regimes also protected wing development against thermal disruption. Because of the roles of the wings in flight and courtship and in view of natural thermal regimes that Drosophila experience, both HS-induction of wing abnormalities and its abatement by PT may have marked effects on Drosophila fitness in nature. Because PT is associated with expression of heat-inducible molecular chaperones such as Hsp70 in Drosophila, we compared thermal disruption of wing development among hsp70 mutants as well as among strains naturally varying in Hsp70 levels. Contrary to expectations, lines or strains with increased Hsp70 levels were no more resistant to HS-disruption of wing development than counterparts with lower Hsp70 levels. In fact, wing development was more resistant to HS in hsp70 deletion strains than control strains. We suggest that, while high Hsp70 levels may aid cells in surviving hyperthermia, high levels may also overly stimulate or inhibit numerous signalling pathways involved in cell proliferation, maturation and programmed death, resulting in developmental failure.


Mol Ecol


Molecular ecology


Williams KD,Helin AB,Posluszny J,Roberts SP,Feder ME




Has Abstract


2003-05-01 00:00:00














  • Population structure of the Chagas disease vector, Triatoma infestans, at the urban-rural interface.

    abstract::The increasing rate of biological invasions resulting from human transport or human-mediated changes to the environment has had devastating ecological and public health consequences. The kissing bug, Triatoma infestans, has dispersed through the Peruvian city of Arequipa. The biological invasion of this insect has res...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Foley EA,Khatchikian CE,Hwang J,Ancca-Juárez J,Borrini-Mayori K,Quıspe-Machaca VR,Levy MZ,Brisson D,Chagas Disease Working Group in Arequipa.

    更新日期:2013-10-01 00:00:00

  • Transposon signatures: species-specific molecular markers that utilize a class of multiple-copy nuclear DNA.

    abstract::Transposable elements are mobile sequences found in nuclear genomes and can potentially serve as molecular markers in various phylogenetic and population genetic investigations. A PCR-based method that utilizes restriction site variation of element copies within a genome is developed. These patterns of site variation,...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Purugganan MD,Wessler SR

    更新日期:1995-04-01 00:00:00

  • Phylogeny and historical aspects of the ecology of eastern Australian scrubwrens Sericornis spp.--evidence from mitochondrial DNA.

    abstract::A phylogeny of mainland eastern Australian scrubwrens (Sericornis citreogularis, S. frontalis, S. keri, S. magnirostris and S. beccarii) was constructed using presence or absence of phylogenetically informative restriction sites in 15 mitochondrial DNA (mtDNA) haplotypes. MtDNA sequence divergences between species wer...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Joseph L,Moritz C

    更新日期:1993-06-01 00:00:00

  • Why UV vision and red vision are important for damselfish (Pomacentridae): structural and expression variation in opsin genes.

    abstract::Coral reefs belong to the most diverse ecosystems on our planet. The diversity in coloration and lifestyles of coral reef fishes makes them a particularly promising system to study the role of visual communication and adaptation. Here, we investigated the evolution of visual pigment genes (opsins) in damselfish (Pomac...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Stieb SM,Cortesi F,Sueess L,Carleton KL,Salzburger W,Marshall NJ

    更新日期:2017-03-01 00:00:00

  • Bayesian inference of a historical bottleneck in a heavily exploited marine mammal.

    abstract::Emerging Bayesian analytical approaches offer increasingly sophisticated means of reconstructing historical population dynamics from genetic data, but have been little applied to scenarios involving demographic bottlenecks. Consequently, we analysed a large mitochondrial and microsatellite dataset from the Antarctic f...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Hoffman JI,Grant SM,Forcada J,Phillips CD

    更新日期:2011-10-01 00:00:00

  • Intrinsic incompatibilities evolving as a by-product of divergent ecological selection: Considering them in empirical studies on divergence with gene flow.

    abstract::The possibility of intrinsic barriers to gene flow is often neglected in empirical research on local adaptation and speciation with gene flow, for example when interpreting patterns observed in genome scans. However, we draw attention to the fact that, even with gene flow, divergent ecological selection may generate i...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Kulmuni J,Westram AM

    更新日期:2017-06-01 00:00:00

  • Genome-wide patterns of divergence and gene flow across a butterfly radiation.

    abstract::The Heliconius butterflies are a diverse recent radiation comprising multiple levels of divergence with ongoing gene flow between species. The recently sequenced genome of Heliconius melpomene allowed us to investigate the genomic evolution of this group using dense RAD marker sequencing. Phylogenetic analysis of 54 i...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Nadeau NJ,Martin SH,Kozak KM,Salazar C,Dasmahapatra KK,Davey JW,Baxter SW,Blaxter ML,Mallet J,Jiggins CD

    更新日期:2013-02-01 00:00:00

  • Host association drives genetic divergence in the bed bug, Cimex lectularius.

    abstract::Genetic differentiation may exist among sympatric populations of a species due to long-term associations with alternative hosts (i.e. host-associated differentiation). While host-associated differentiation has been documented in several phytophagus insects, there are far fewer cases known in animal parasites. The bed ...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Booth W,Balvín O,Vargo EL,Vilímová J,Schal C

    更新日期:2015-03-01 00:00:00

  • Complex patterns of colonization and refugia revealed for European grayling Thymallus thymallus, based on complete sequencing of the mitochondrial DNA control region.

    abstract::The complete mitochondrial DNA (mtDNA) control region (1043 base pairs) and 162-bp of flanking transfer RNA genes were sequenced in 316 European grayling, Thymallus thymallus, from 44 populations throughout the Western European range of the species. A total of 58 haplotypes were revealed with pairwise divergence rangi...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Weiss S,Persat H,Eppe R,Schlötterer C,Uiblein F

    更新日期:2002-08-01 00:00:00

  • Genetic patterns across an invasion's history: a test of change versus stasis for the Eurasian round goby in North America.

    abstract::Biological invasions comprise accidental evolutionary experiments, whose genetic compositions underlie relative success, spread and persistence in new habitats. However, little is known about whether, or how, their population genetic patterns change temporally and/or spatially across the invasion's history. Theory pre...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Snyder MR,Stepien CA

    更新日期:2017-02-01 00:00:00

  • Genetic structuring and recent demographic history of red pandas (Ailurus fulgens) inferred from microsatellite and mitochondrial DNA.

    abstract::Clarification of the genetic structure and population history of a species can shed light on the impacts of landscapes, historical climate change and contemporary human activities and thus enables evidence-based conservation decisions for endangered organisms. The red panda (Ailurus fulgens) is an endangered species d...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Hu Y,Guo Y,Qi D,Zhan X,Wu H,Bruford MW,Wei F

    更新日期:2011-07-01 00:00:00

  • Evolutionary trade-offs of insecticide resistance - The fitness costs associated with target-site mutations in the nAChR of Drosophila melanogaster.

    abstract::The evolution of resistance to drugs and pesticides poses a major threat to human health and food security. Neonicotinoids are highly effective insecticides used to control agricultural pests. They target the insect nicotinic acetylcholine receptor and mutations of the receptor that confer resistance have been slow to...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Homem RA,Buttery B,Richardson E,Tan Y,Field LM,Williamson MS,Emyr Davies TG

    更新日期:2020-07-01 00:00:00

  • Paternal effects in a wild-type zebrafish implicate a role of sperm-derived small RNAs.

    abstract::While the importance of maternal effects has long been appreciated, a growing body of evidence now points to the paternal environment having an important influence on offspring phenotype. Indeed, research on rodent models suggests that paternal stress leaves an imprint on the behaviour and physiology of offspring via ...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Ord J,Heath PR,Fazeli A,Watt PJ

    更新日期:2020-07-01 00:00:00

  • Ecological patterns and genetic analysis of post-dispersal seed predation in sunflower (Helianthus annuus) crop-wild hybrids.

    abstract::Crop-wild hybridization has been documented in many cultivated species, but the ecological and genetic factors that influence the likelihood or rate that cultivar alleles will introgress into wild populations are poorly understood. Seed predation is one factor that could mitigate the spread of otherwise advantageous c...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Dechaine JM,Burger JC,Burke JM

    更新日期:2010-08-01 00:00:00

  • The effect of habitat fragmentation on the genetic structure of a top predator: loss of diversity and high differentiation among remnant populations of Atlantic Forest jaguars (Panthera onca).

    abstract::Habitat fragmentation may disrupt original patterns of gene flow and lead to drift-induced differentiation among local population units. Top predators such as the jaguar may be particularly susceptible to this effect, given their low population densities, leading to small effective sizes in local fragments. On the oth...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Haag T,Santos AS,Sana DA,Morato RG,Cullen L Jr,Crawshaw PG Jr,De Angelo C,Di Bitetti MS,Salzano FM,Eizirik E

    更新日期:2010-11-01 00:00:00

  • Ecological drift and local exposures drive enteric bacterial community differences within species of Galápagos iguanas.

    abstract::Diet strongly influences the intestinal microbial communities through species sorting. Alternatively, these communicates may differ because of chance variation in local microbial exposures or species losses among allopatric host populations (i.e. ecological drift). We investigated how these forces shape enteric commun...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Lankau EW,Hong PY,Mackie RI

    更新日期:2012-04-01 00:00:00

  • Differential gene expression during thermal stress and bleaching in the Caribbean coral Montastraea faveolata.

    abstract::The declining health of coral reefs worldwide is likely to intensify in response to continued anthropogenic disturbance from coastal development, pollution, and climate change. In response to these stresses, reef-building corals may exhibit bleaching, which marks the breakdown in symbiosis between coral and zooxanthel...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: DeSalvo MK,Voolstra CR,Sunagawa S,Schwarz JA,Stillman JH,Coffroth MA,Szmant AM,Medina M

    更新日期:2008-09-01 00:00:00

  • Recent Y chromosome divergence despite ancient origin of dioecy in poplars (Populus).

    abstract::All species of the genus Populus (poplar, aspen) are dioecious, suggesting an ancient origin of this trait. Despite some empirical counter examples, theory suggests that nonrecombining sex-linked regions should quickly spread, eventually becoming heteromorphic chromosomes. In contrast, we show using whole-genome scans...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Geraldes A,Hefer CA,Capron A,Kolosova N,Martinez-Nuñez F,Soolanayakanahally RY,Stanton B,Guy RD,Mansfield SD,Douglas CJ,Cronk QC

    更新日期:2015-07-01 00:00:00

  • Phylogenetic diversity of Sri Lankan freshwater crabs and its implications for conservation.

    abstract::As part of a Global Biodiversity Hotspot, the conservation of Sri Lanka's endemic biodiversity warrants special attention. With 51 species (50 of them endemic) occurring in the island, the biodiversity of freshwater crabs is unusually high for such a small area (65,600 km(2)). Freshwater crabs have successfully coloni...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Beenaerts N,Pethiyagoda R,Ng PK,Yeo DC,Bex GJ,Bahir MM,Artois T

    更新日期:2010-01-01 00:00:00

  • The Baltic Sea as a model system for studying postglacial colonization and ecological differentiation, exemplified by the red alga Ceramium tenuicorne.

    abstract::The Baltic Sea provides a unique model system for studying genetic effects of postglacial colonization and ecological differentiation, because all marine organisms must have immigrated after the opening of the Danish Straits 8000 years ago and responded to the development of the steep Skagerrak-Baltic salinity gradien...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Gabrielsen TM,Brochmann C,Rueness J

    更新日期:2002-10-01 00:00:00

  • Phylogeography of the barbel (Barbus barbus) assessed by mitochondrial DNA variation.

    abstract::Using the phylogeographic framework, we assessed the DNA sequence variation at the mitochondrial cytochrome b gene across the distribution range of the barbel Barbus barbus, a widely distributed European cyprinid. Reciprocal monophyly of non-Mediterranean European and Balkan/Anatolian populations is taken as evidence ...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Kotlík P,Berrebi P

    更新日期:2001-09-01 00:00:00

  • Crossing the uncrossable: novel trans-valley biogeographic patterns revealed in the genetic history of low-dispersal mygalomorph spiders (Antrodiaetidae, Antrodiaetus) from California.

    abstract::Antrodiaetus riversi is a dispersal-limited, habitat-specialized mygalomorph spider species endemic to mesic woodlands of northern and central California. Here, we build upon prior phylogeographic research using a much larger geographic sample and include additional nuclear genes, providing more detailed biogeographic...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Hedin M,Starrett J,Hayashi C

    更新日期:2013-01-01 00:00:00

  • Phylogeography of a high-dispersal New Zealand sea-star: does upwelling block gene-flow?

    abstract::New Zealand's (NZ) geographical isolation, extensive coastline and well-characterized oceanography offer a valuable system for marine biogeographical research. Here we use mtDNA control region sequences in the abundant endemic sea-star Patiriella regularis to test the following literature-based predictions: that coast...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Waters JM,Roy MS

    更新日期:2004-09-01 00:00:00

  • Plants and tortoises: mutations in the Arabidopsis jasmonate pathway increase feeding in a vertebrate herbivore.

    abstract::Photosynthetic tissues, the major food source of many invertebrates and vertebrates, are well defended. Many defence traits in leaves are controlled via the jasmonate signalling pathway in which jasmonate acts as a hormone by binding to a receptor to activate responses that lead to increased resistance to invertebrate...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Mafli A,Goudet J,Farmer EE

    更新日期:2012-05-01 00:00:00

  • Colonization and dispersal in a social species, the Bechstein's bat (Myotis bechsteinii).

    abstract::Metapopulation genetic models consider that colonization and dispersal are distinct behaviours. However, whether colonization and dispersal indeed reflect different biological processes in nature is unclear. One possibility to test this assumption is to assess patterns of autosomal and mitochondrial genetic structure ...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Kerth G,Petit E

    更新日期:2005-11-01 00:00:00

  • Genetic diversity of Ranunculus acris L. (Ranunculaceae) populations in relation to species diversity and habitat type in grassland communities.

    abstract::Correlates between genetic diversity at intra- and interpopulation levels and the species diversity in plant communities are rarely investigated. Such correlates may give insights into the effect of local selective forces across different communities on the genetic diversity of local plant populations. This study has ...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Odat N,Jetschke G,Hellwig FH

    更新日期:2004-05-01 00:00:00

  • Larvae of related Diptera species from thermally contrasting habitats exhibit continuous up-regulation of heat shock proteins and high thermotolerance.

    abstract::A population of Stratiomys japonica, a species belonging to the family Stratiomyidae (Diptera), common name 'soldier flies', occurs in a hot volcanic spring, which is apparently among the most inhospitable environments for animals because of chemical and thermal conditions. Larvae of this species, which naturally ofte...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Garbuz DG,Zatsepina OG,Przhiboro AA,Yushenova I,Guzhova IV,Evgen'ev MB

    更新日期:2008-11-01 00:00:00

  • Genomic evidence for gene flow between monarchs with divergent migratory phenotypes and flight performance.

    abstract::Monarch butterflies are known for their spectacular annual migration in eastern North America, with millions of monarchs flying up to 4,500 km to overwintering sites in central Mexico. Monarchs also live west of the Rocky Mountains, where they travel shorter distances to overwinter along the Pacific Coast. It is often...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Talla V,Pierce AA,Adams KL,de Man TJB,Nallu S,Villablanca FX,Kronforst MR,de Roode JC

    更新日期:2020-07-01 00:00:00

  • The geographical and environmental determinants of genetic diversity for four alpine conifers of the European Alps.

    abstract::Climate is one of the most important drivers of local adaptation in forest tree species. Standing levels of genetic diversity and structure within and among natural populations of forest trees are determined by the interplay between climatic heterogeneity and the balance between selection and gene flow. To investigate...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Mosca E,Eckert AJ,Di Pierro EA,Rocchini D,La Porta N,Belletti P,Neale DB

    更新日期:2012-11-01 00:00:00

  • Independent origins and horizontal transfer of bacterial symbionts of aphids.

    abstract::Many insect groups have obligate associations with primary endosymbionts: mutualistic bacteria that are maternally transmitted and derived from an ancient infection. Often, the same insects are hosts to 'secondary' bacterial symbionts which are maternally transmitted but relatively labile within host lineages. To expl...

    journal_title:Molecular ecology

    pub_type: 杂志文章


    authors: Sandström JP,Russell JA,White JP,Moran NA

    更新日期:2001-01-01 00:00:00