Fatal pulmonary thromboembolism after successful transsphenoidal hypophysectomy for Cushing's disease.

Abstract:

:We have reported the case of a 30-year-old woman with Cushing's disease who died of massive pulmonary thromboembolism 5 weeks after successful transsphenoidal hypophysectomy. Glucocorticoid excess appears to cause a hypercoagulable state, and consideration of this thromboembolic propensity and its potential duration after cure is indicated in all patients with Cushing's syndrome during the perioperative period. At the present time, we recommend the routine perioperative use of intermittent pneumatic compression in all patients with Cushing's disease or Cushing's syndrome.

journal_name

South Med J

journal_title

Southern medical journal

authors

Jackson JA,Trowbridge A,Smigiel M

doi

10.1097/00007611-199008000-00026

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

960-2

issue

8

eissn

0038-4348

issn

1541-8243

journal_volume

83

pub_type

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