In vitro anesthetic washin and washout via bubble oxygenators: influence of anesthetic solubility and rates of carrier gas inflow and pump blood flow.

abstract：BACKGROUND:A potential physicochemical interaction between epidural local anesthetics and extended-release epidural morphine (EREM) could negate the sustained release. In this study, we sought to determine the pharmacokinetic and drug effects of prior epidural lidocaine administration on EREM. METHODS:Thirty healthy w...

journal_title：Anesthesia and analgesia

authors： Atkinson Ralls L,Drover DR,Clavijo CF,Carvalho B

更新日期：2011-08-01 00:00:00

abstract：:Both clonidine, an alpha(2) agonist, and morphine, an opioid agonist, provide enhanced patient analgesia after arthroscopic knee surgery when administered via the intraarticular (IA) route. Clonidine potentiates morphine analgesia in the animal model. We designed this study to determine whether clonidine or morphine r...

journal_title：Anesthesia and analgesia

authors： Joshi W,Reuben SS,Kilaru PR,Sklar J,Maciolek H

更新日期：2000-05-01 00:00:00

abstract：:While a large number of studies has examined the efficacy of opioid-sparing analgesics in adult surgical populations, fewer studies are available to guide postoperative pain treatment in pediatric patients. We systematically reviewed available publications on the use of systemic nonopioid agents for postoperative anal...

journal_title：Anesthesia and analgesia

authors： Zhu A,Benzon HA,Anderson TA

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Thoracic aorta dissection is an acute critical condition associated with shock-induced endotheliopathy, coagulopathy, massive bleeding, and significant morbidity and mortality. Our aim was to compare the effect of coagulation support with solvent/detergent-treated pooled plasma (OctaplasLG) versus standard f...

journal_title：Anesthesia and analgesia

authors： Stensballe J,Ulrich AG,Nilsson JC,Henriksen HH,Olsen PS,Ostrowski SR,Johansson PI

更新日期：2018-10-01 00:00:00

abstract：UNLABELLED:We studied lung function in children with and without asthma receiving anesthesia with sevoflurane. Fifty-two children had anesthesia induced with sevoflurane (up to 8%) in a mixture of 50% nitrous oxide in oxygen and then maintained at 3% with children breathing spontaneously via face mask and Jackson-Rees ...

journal_title：Anesthesia and analgesia

authors： Habre W,Scalfaro P,Sims C,Tiller K,Sly PD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:While transfusion-related acute lung injury (TRALI) remains the primary cause of transfusion-related fatalities (37%), recent reports estimate the incidence of TRALI at 0.008% per unit of plasma transfused and 0.004% per all products transfused. Because blood banks have moved toward male-predominant plasma, ...

journal_title：Anesthesia and analgesia

authors： Meyer DE,Reynolds JW,Hobbs R,Bai Y,Hartwell B,Pommerening MJ,Fox EE,Wade CE,Holcomb JB,Cotton BA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The Perioperative Surgical Home (PSH) seeks to remedy the currently highly fragmented and expensive perioperative care in the United States. The 2 specific aims of this health services research study were to assess the association between the preoperative and postoperative elements of an initial PSH model an...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Barman J,Hunter JM Jr,Jones KA,Pittet JF

更新日期：2017-05-01 00:00:00

abstract：:The safety and utility of pediatric epidural analgesia is well established, but the risk of permanent neurological injury is unknown and largely must be extrapolated from adult literature. In this article we present a series of 4 cases of longterm or permanent neurologic complications associated with epidural analgesi...

journal_title：Anesthesia and analgesia

authors： Meyer MJ,Krane EJ,Goldschneider KR,Klein NJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the ...

journal_title：Anesthesia and analgesia

authors： Segal S,Pancaro C,Bonney I,Marchand JE

更新日期：2017-12-01 00:00:00

abstract：:High blood concentrations of local anesthetics are cardiotoxic. The aim of this study was to compare the effects of lidocaine and bupivacaine on the intrinsic pacemaker activity of in vitro sinoatrial nodal cells of the adult and neonatal guinea pig in the presence and absence of hypoxia and acidosis. Fifteen pairs of...

journal_title：Anesthesia and analgesia

authors： Bosnjak ZJ,Stowe DF,Kampine JP

更新日期：1986-09-01 00:00:00

abstract：UNLABELLED:The aim of this study was to examine the antiallodynic and antinociceptive effects of subcutaneously administered physostigmine (50, 100, 200 micrograms/kg), compared with morphine (2.5, 5, 10 mg/kg) and NaCl after spinal nerve ligation in rats. The following stimuli were used: acetone (cold allodynia), von ...

journal_title：Anesthesia and analgesia

authors： Pöyhiä R,Xu M,Kontinen VK,Paananen S,Kalso E

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:There is a considerable discrepancy between the reported incidences of awareness under anesthesia in children (0.2%-2.7%). In this prospective, observational, cohort study we evaluated 1) the incidence of awareness during general anesthesia in children across three settings, 2) factors contributing to awaren...

journal_title：Anesthesia and analgesia

authors： Malviya S,Galinkin JL,Bannister CF,Burke C,Zuk J,Popenhagen M,Brown S,Voepel-Lewis T

更新日期：2009-11-01 00:00:00

abstract：UNLABELLED:In the present study, we assessed the potential effect of nitroglycerin IV (NTG), a donor of exogenous nitric oxide, on metabolic coronary flow control in patients with coronary artery disease. In 12 patients scheduled for coronary artery surgery, arterial blood pressure, pulmonary capillary wedge pressure, ...

journal_title：Anesthesia and analgesia

authors： Kal JE,Vergroesen I,van Wezel HB

更新日期：1999-02-01 00:00:00

abstract：UNLABELLED:As the surgical population ages, the number of patients presenting with coronary artery disease and age-related loss of pulmonary recoil will increase. Although their influence on gas exchange in this population remains unknown, sevoflurane and isoflurane are used for an increasing variety of surgical proced...

journal_title：Anesthesia and analgesia

authors： Loeckinger A,Keller C,Lindner KH,Kleinsasser A

更新日期：2002-05-01 00:00:00

abstract：UNLABELLED:The purpose of this animal investigation was to compare behavioral responses with spinal Fos-like immunoreactivity (FLI) after pre-versus postformalin administration of anesthetic doses of IV ketamine or alfentanil. Preformalin and postformalin injection (1.5% subcutaneously) treatment groups included IV sal...

journal_title：Anesthesia and analgesia

authors： Gilron I,Quirion R,Coderre TJ

更新日期：1999-07-01 00:00:00

abstract：:Hepatic blood flow and the oxygen supply/uptake relation were studied in 19 miniature pigs using labeled microspheres. Changes in hepatic arterial blood flow and portal blood flow, as well as total hepatic blood flow during halothane anesthesia were more closely associated with changes in mean arterial pressure (MAP) ...

journal_title：Anesthesia and analgesia

authors： Gelman S,Dillard E,Bradley EL Jr

更新日期：1987-10-01 00:00:00

abstract：UNLABELLED:There is concern that the environment in which consent for anesthesia research is sought may be coercive. We therefore designed this study to determine the factors that parents consider in consenting to their child's participation in clinical anesthesia research. The study sample consisted of 246 parents who...

journal_title：Anesthesia and analgesia

authors： Tait AR,Voepel-Lewis T,Siewert M,Malviya S

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:A lighted stylet is an effective alternative to a direct laryngoscope and has been reported to be particularly useful in patients with difficult airways. A high Mallampati class indicates poor visibility of the oropharyngeal structures. Because a lighted stylet does not require direct oropharyngeal visualiza...

journal_title：Anesthesia and analgesia

authors： Rhee KY,Lee JR,Kim J,Park S,Kwon WK,Han S

更新日期：2009-04-01 00:00:00

abstract：UNLABELLED:We compare hemodynamic responses in normotensive and hypertensive anesthetized paralyzed patients among three intubation devices: the Macintosh laryngoscope (LS), the Trachlight lightwand (LW), and the intubating laryngeal mask airway Fastrach (ILM). Seventy-five normotensive and 75 hypertensive patients wer...

journal_title：Anesthesia and analgesia

authors： Kihara S,Brimacombe J,Yaguchi Y,Watanabe S,Taguchi N,Komatsuzaki T

更新日期：2003-03-01 00:00:00

abstract：:The purpose of this study was to determine whether injection rate affects the spread of hypobaric spinal anesthesia. Hypobaric spinal anesthesia was performed on 20 patients for total hip arthroplasty. Dural puncture was performed with a 22-gauge Whitacre needle. All patients received 10 mg of hypobaric tetracaine wit...

journal_title：Anesthesia and analgesia

authors： Atchison SR,Wedel DJ,Wilson PR

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Adverse effects of hydroxyethyl starches (HESs) have been verified in patients suffering from sepsis or kidney disease, but not in surgical patients at large. The investigation aimed to determine whether the use of HES 130/0.4 was associated with the incidence of acute postinterventional adverse events compa...

journal_title：Anesthesia and analgesia

authors： Pagel JI,Rehm M,Kammerer T,Hulde N,Speck E,Briegel J,Reinholz F,Crispin A,Hofmann-Kiefer KF

更新日期：2018-06-01 00:00:00

abstract：:The purpose of the present study was to assess patients' anxiety level and information requirement in the preoperative phase. During routine preoperative screening, 320 patients were asked to assess their anxiety and information requirement on a six-item questionnaire, the Amsterdam Preoperative Anxiety and Informatio...

journal_title：Anesthesia and analgesia

authors： Moerman N,van Dam FS,Muller MJ,Oosting H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Respiratory variations in arterial pulse pressure (DeltaPP) are accurate predictors of fluid responsiveness in mechanically ventilated patients. The aim of our study was to assess the ability of a novel algorithm for automatic estimation of stroke volume variation (SVV) to predict fluid responsiveness in mec...

journal_title：Anesthesia and analgesia

authors： Cannesson M,Musard H,Desebbe O,Boucau C,Simon R,Hénaine R,Lehot JJ

更新日期：2009-02-01 00:00:00

abstract：UNLABELLED:We tested the ability of electroconvulsive treatment (ECT) to block thermal hyperalgesia and mechanical allodynia in rats with peripheral neuropathy. Repeated ECT (six times daily) significantly reduced thermal hyperalgesia 48 h after the end of the final treatment but had no significant effects on mechanica...

journal_title：Anesthesia and analgesia

authors： Shibata M,Wakisaka S,Inoue T,Shimizu T,Yoshiya I

更新日期：1998-03-01 00:00:00

abstract：UNLABELLED:There has been growing interest in determining the possible immune consequences of opioid administration for the management of postoperative pain. We studied the effects of morphine and tramadol on pain and immune function during the postoperative period in 30 patients undergoing abdominal surgery for uterin...

journal_title：Anesthesia and analgesia

authors： Sacerdote P,Bianchi M,Gaspani L,Manfredi B,Maucione A,Terno G,Ammatuna M,Panerai AE

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Pulmonary aspiration of gastric contents is associated with significant perioperative morbidity and mortality. Previous studies have investigated the validity, reliability, and possible clinical impact of gastric ultrasound for the assessment of gastric content at the bedside. In the present study, we examin...

journal_title：Anesthesia and analgesia

authors： Kruisselbrink R,Gharapetian A,Chaparro LE,Ami N,Richler D,Chan VWS,Perlas A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Insufficient fixation of an epidural catheter may result in migration of the catheter and eventual catheter failure. However, the best fixation method remains to be established. Aron Alpha A (2-ethyl cyanoacrylate) adhesive is approved for clinical use and can be used for surgical adhesion to both skin and b...

journal_title：Anesthesia and analgesia

authors： Tadokoro T,Kakinohana M,Navarro M,Goya M,Odo Y

更新日期：2019-07-01 00:00:00

abstract：:The effects of continuous epidural anesthesia and of general anesthesia on the incidence of thromboembolism following total hip replacement were studied. Sixty patients were randomly allotted to one of two groups receiving either epidural or general anesthesia. Epidural anesthesia (N = 30) consisted of 0.5% bupivacain...

journal_title：Anesthesia and analgesia

authors： Modig J,Borg T,Karlström G,Maripuu E,Sahlstedt B

更新日期：1983-02-01 00:00:00

abstract：:The effects of commercial and crystalline solutions of chloroprocaine (CP) (1.6 X 10(-3)-0.4 X 10(-3)M) and sodium bisulfite (SB) (0.8 X 10(-3)-0.08 X 10(-3)M) were studied on the multiplication of human neuroblastoma cells. These cells were chosen because of putative neurotoxicity associated with CP; cell multiplicat...

journal_title：Anesthesia and analgesia

authors： Seravalli E,Lear E

更新日期：1987-10-01 00:00:00

abstract：:The effects of nitrous oxide-oxygen plus small doses of fentanyl with (N = 7) and without (N = 15) naloxone and the effects of nitrous oxide-oxygen plus halothane (N = 13) on plasma concentration of arginine vasopressin (AVP) and cortisol were studied in normal patients before and during gynecologic laparotomies. Pati...

journal_title：Anesthesia and analgesia

authors： Lehtinen AM,Fyhrquist F,Kivalo I

更新日期：1984-01-01 00:00:00