Abstract:
:A seven-month-old male child was brought in for an eye test for poor vision and nystagmus noticed from four months of age. The child had delayed milestones of development and multiple (six times) episodes of unexplained lower respiratory tract infection (from two months of age) treated by pediatricians at different centers without complete cure. Fundus examination showed bilateral cherry-red spots at the macula. There were diffusely distributed hyper-pigmented patches (Mongolian spots) on the back and extensor aspect of the extremities. The case was sent back to the pediatricians for a re-evaluation to rule out storage disorder. Lysosomal enzyme assay in the leucocytes showed a significantly reduced β-galactosidase level (15.6 nmol/hr/mg protein in contrast to a normal range of 79.6 to 480.0). This confirmed the patient to be a case of lysosomal storage disease, the GM1 gangliosidosis (type I).
journal_name
Semin Ophthalmoljournal_title
Seminars in ophthalmologyauthors
Padhi TR,Pattnaik S,Kesarwani S,Das Tdoi
10.3109/08820538.2013.835848subject
Has Abstractpub_date
2015-05-01 00:00:00pages
224-6issue
3eissn
0882-0538issn
1744-5205journal_volume
30pub_type
杂志文章abstract:PURPOSE:To assess amniotic membrane retention after amniotic membrane transplant in bullous keratopathy patients and whether there were any corneal structural changes that may hinder further penetrating keratoplasty Methods: A retrospective study including 22 patients who have undergone amniotic membrane transplant fro...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2019.1620790
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To report a case of fungal corneal ulcer and bacterial orbital cellulitis as complications of bacterial endophthalmitis following cataract surgery. METHODS:A 51-year-old man underwent anterior chamber irrigation and aspiration in the left eye one day after cataract surgery because of bacterial endophthalmitis....
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2012.760613
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To characterize anatomical dimensions of a disc notch using novel methods using spectral domain optical coherence tomography (SD-OCT). PARTICIPANTS:All age- and severity-matched glaucoma patients with disc notch (defined as complete loss of neural rim with no residual rim between disc and cup) seen from 2014 t...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2018.1540709
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:We hypothesized that the ongoing neurotrophic effects of electroconvulsive therapy (ECT) might be detected in the retinal nerve fiber layer (RNFL) using optical coherence tomography (OCT). METHODS:This study was conducted using a prospective design. The RNFL thickness alterations of 18 psychiatric patients ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2018.1538419
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To employ optical coherence tomography (OCT) to examine the relationship of changes in the retinal nerve fiber layer (RNFL) and macular thickness as well as ganglion cell (GC) parameters with the stage of keratoconus (KC), and to compare these changes with a control group. METHODS:A total of 84 eyes of 68 pati...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2016.1169302
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To evaluate refractive errors in patients with migraine headache and to compare with healthy subjects. MATERIALS AND METHODS:This prospective case-control study includes patients with migraine and age- and sex-matched healthy subjects. Clinical and demographic characteristics of the patients were noted. Detail...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2014.962177
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:We would like to describe a case report of posterior ischemic optic neuropathy (PION) misdiagnosed as arteritic PION with presumed GCA which leads to missing the correct diagnosis with fatal outcome. METHODS:The clinical course of a single patient will be described including presentation, testing,diagnosis a...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820530903392902
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To evaluate the results of scleral-fixated posterior chamber intraocular lenses (SFIOL) in pediatric and adult patients. METHODS:We carried out a retrospective analysis of 129 eyes of 120 patients (adult group, n = 96; pediatric group, n = 24) who underwent SFIOL implantation. Outcome measures were indications...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.835834
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To evaluate the outcomes of patients with vitreomacular traction syndrome (VMT) treated with triamcinolone acetonid (TA) assisted 23-gauge (23-G) transconjunctival sutureless vitrectomy. METHODS:Restrospective, case series. The medical charts of 13 eyes of 13 consecutive patients with VMT who underwent 23-gaug...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2012.680640
更新日期:2012-05-01 00:00:00
abstract:INTRODUCTION:Consumer-grade virtual reality (VR) headset is being used with increasing frequency nowadays, however, the effect on visual function is not clear. OBJECTIVES:We here investigate whether using VR headset changes adults' visual function and take into account the possible factors. METHODS:We compared the un...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2020.1776342
更新日期:2020-04-02 00:00:00
abstract:PURPOSE:To evaluate the relationship between lens density using the Scheimpflug system and phacodynamics in nuclear cataracts as related to patient age. METHODS:In 262 eyes with nuclear cataracts, the objective lens density was determined by Pentacam Nucleus Staging (PNS) software while subjective grading was achieved...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2015.1120756
更新日期:2017-01-01 00:00:00
abstract::Transpupillary thermotherapy (TTT) has been suggested as a putative treatment for choroidal neovascularization (CNV) in age-related macular degeneration (AMD). This prospective study comprised 66 consecutive patients referred for exudative AMD with predominantly occult subfoveal CNV. Based on fluorescein angiography, ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1076/soph.16.2.90.4210
更新日期:2001-06-01 00:00:00
abstract:PURPOSE:To report a novel plasminogen gene mutation and detection of anti-plasminogen antibodies in a patient with ligneous conjunctivitis successfully treated with 60% fresh frozen plasma (FFP). METHODS:Retrospective data collected on a 45-year-old Caucasian female presenting with unilateral chronic membranous lesion...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2015.1005319
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To identify the patterns of ocular injury and to determine ocular morbidity resulting from the use of firecrackers. METHODS:A prospective observational study of all patients presenting with ocular trauma consequent to fireworks usage in a tertiary eye care center in South India over a one-month period around t...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2014.962157
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. METHODS:This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old we...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1080/08820538.2018.1506483
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To describe utilization trends of an ophthalmology-specific emergency department (ED). METHODS:Prospective cohort study of new patients presenting in the ophthalmology ED for at least a 30-day period in the spring of each year for five consecutive years (2010-14) at a university referral center. A data form,...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2016.1188129
更新日期:2018-01-01 00:00:00
abstract::Paroxysmal hemicrania is a trigeminal autonomic cephalalgia first described in 1976, characterized by episodic attacks of excruciating unilateral periorbital and temporal stabbing, pulsatile, craw-like, or boring headaches lasting 2 - 30 minutes, accompanied by autonomic features, and alleviated by indomethacin. Parox...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820531003635505
更新日期:2010-01-01 00:00:00
abstract::Conventional suprathreshold retinal photocoagulation is a destructive procedure, but chorioretinal damage can be decreased by changing laser parameters and clinical endpoints. Laser effects can be localized by decreasing laser wavelength, spot size, and exposure duration, as well as by adopting threshold or subthresho...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539909069538
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Glaucoma is one of the leading causes of blindness worldwide. Treatment is still largely targeted at lowering intraocular pressure. Intraocular pressures can be lowered through a variety of topical medications, lasers and incisional surgeries. There are currently several classes of topical medications availa...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2020.1818796
更新日期:2020-08-17 00:00:00
abstract::The opportunity to perform two or more ophthalmic operations simultaneously has increased in recent years. In keratoplasty too, the simultaneous operation consisting of cataract extraction and IOL insertion (triple procedure) has become common. Penetrating keratoplasty (PKP) and planned extracapsular cataract extracti...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1076/soph.16.3.126.4197
更新日期:2001-09-01 00:00:00
abstract::New translational research has paved the way for more optimistic management of melanoma. Medications targeting oncogenic signaling cascades and immune regulatory molecules have significantly improved overall survival for patients with metastatic melanoma. While isolated, operable orbital melanoma may still benefit fro...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2015.1114849
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:Vascular anomalies comprise malformations, hemangiomas, and rare tumors. The commonality among these lesions is their origin in vascular endothelia. Most occur sporadically, but occasional inheritance is observed and thus allows genetic research and insight into etiology. This review highlights those vascular a...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2013.825279
更新日期:2013-09-01 00:00:00
abstract::Retrospective analysis of epidemiological and clinical characteristics of patients diagnosed with benign essential blepharospasm and hemifacial spasm who reported to the oculoplasty clinic of a tertiary eye care center in north India between January 2010 and April 2015 was carried out. Dry eye, as well as all the loca...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2015.1096401
更新日期:2017-01-01 00:00:00
abstract::The lacrimal caruncle is a modified cutaneous tissue that contains hair follicles, accessory lacrimal glands, sweat glands, lobules of fat, and sebaceous glands. Due to the nature of tissue, a variety of lesions, both benign and malignant, could arise from this area. Lymphomas of the eye and its adnexa are frequently ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.833260
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:To present a unique case of a 33-year-old woman using paroxetine who presented with acute unilateral visual loss due to chronic angle-closure glaucoma. METHODS:Case report. RESULTS:A 33-year-old women who had been under paroxetine treatment for the past four months presented at the emergency room due to a sud...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.771193
更新日期:2013-07-01 00:00:00
abstract::Purpose: To compare the success rates and safety of transscleral cyclophotocoagulation (TSCPC) for the treatment of refractory glaucoma using the slow coagulation technique and the conventional technique. Methods: A retrospective, interventional case series of 44 patients (44 eyes) who underwent TSCPC using the slow c...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2019.1638946
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy and safety of a modified double extra sharp chopper for removal of hard cataracts. DESIGN:Prospective non-comparative interventional clinical study. PARTICIPANTS:Forty eyes from 25 patients with hard mature cataract grades 3-4. METHODS:The pre-modified Koch chopper was sharpened unde...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2010.482846
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To present a case of unilateral development of severe corneal vascularization in the eye of a keratoconic patient implanted with Intacs microthin prescription inserts and concurrent bilateral use of rigid gas permeable (RGP) contact lenses. METHODS:A 20-year-old male underwent unilateral implantation of Intacs...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2011.588646
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:Investigate risk factors for unplanned return to the operating room after resident-performed cataract surgery. DESIGN:Retrospective case-control study. SETTING:Institutional. METHODS:Study population: All patients with reoperation within 90 days of resident-performed phacoemulsification were matched to fou...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2016.1208760
更新日期:2018-01-01 00:00:00
abstract::Primary intraocular lymphoma (PIOL) is a type of primary central nervous system lymphoma (PCNSL). It is the most common neoplastic masquerade syndrome involving the eye. Its protean ocular manifestations, plus in many cases the initial positive response to corticosteroid therapy for presumed uveitis, delay accurate di...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530500350498
更新日期:2006-07-01 00:00:00