Abstract:
PURPOSE:To present a unique case of a 33-year-old woman using paroxetine who presented with acute unilateral visual loss due to chronic angle-closure glaucoma. METHODS:Case report. RESULTS:A 33-year-old women who had been under paroxetine treatment for the past four months presented at the emergency room due to a sudden loss of visual acuity (VA) in the left eye (LE). Narrow anterior chamber was detected. Intraocular pressure (IOP) was 29 mmHg right eye (RE) and 42 mm Hg LE. A fundus exam revealed a cup-to-disc ratio of 0.9-1 for the LE and of 0.1-0.2 for the RE. Paroxetine treatment was suspended, and after 48 h IOP was 10 mm Hg in both eyes (BE). ND-YAG laser iridotomy was performed in BE. In the subsequent visit, IOP was 25 mm Hg in the RE and 41 mm Hg in the LE; on her own initiative the patient had resumed paroxetine treatment. After requesting the patient again to stop taking the anti-depressant, IOP was 10 mm Hg in BE in the next exam 48 h later. CONCLUSIONS:As far as we are aware, there are no other reports of chronic angle-closure glaucoma related to the use of paroxetine. We thus consider that, before initiating treatment with this drug, patients should be informed of its potential ocular risks and they should be subjected to an ophthalmologic examination before its use is authorized.
journal_name
Semin Ophthalmoljournal_title
Seminars in ophthalmologyauthors
Sierra-Rodriguez MA,Saenz-Frances F,Santos-Bueso E,Garcia-Feijoo J,Gonzelez-Romero JCdoi
10.3109/08820538.2013.771193subject
Has Abstractpub_date
2013-07-01 00:00:00pages
244-6issue
4eissn
0882-0538issn
1744-5205journal_volume
28pub_type
杂志文章abstract:PURPOSE:To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. METHODS:This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old we...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1080/08820538.2018.1506483
更新日期:2018-01-01 00:00:00
abstract::Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, and the advent of anti-vascular endothelial growth factor agents (VEGF) has revolutionized treatment for neovascular AMD. Two of the most popular anti-VEGF agents, ranibizumab (Lucentis; Genentech/Roche) and bevacizumab (Avastin; ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2016.1154174
更新日期:2016-01-01 00:00:00
abstract::Autosomal dominant hereditary optic atrophy (ADOA), also known as Kjer's syndrome, is a common hereditary cause of progressive bilateral vision loss. Recent advancements in the understanding of the genetics of this condition have revealed that a single gene may account for a large portion of the clinical manifestation...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2013.825296
更新日期:2013-09-01 00:00:00
abstract::Purpose: To evaluate detailed corneal parameters of inflammatory bowel disease (IBD) patients, including Crohn's disease (CD) and ulcerative colitis (UC) patients, and to assess associations between anterior segment values and other clinical variables.Methods: This prospective cross-sectional case-control study at a t...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2019.1684525
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To identify the patterns of ocular injury and to determine ocular morbidity resulting from the use of firecrackers. METHODS:A prospective observational study of all patients presenting with ocular trauma consequent to fireworks usage in a tertiary eye care center in South India over a one-month period around t...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2014.962157
更新日期:2016-01-01 00:00:00
abstract::In the herpetic stromal keratitis (HSK), HSV DNA fragments and HSV-IgG immune complexes (HSV-IC) are present in most of the corneas long after infective virus has disappeared. These viral components are highly immunogenic and potentiate production of proinflammatory cytokines and chemokines via Toll-like receptors (TL...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530802111408
更新日期:2008-07-01 00:00:00
abstract::Transpupillary thermotherapy (TTT) has been suggested as a putative treatment for choroidal neovascularization (CNV) in age-related macular degeneration (AMD). This prospective study comprised 66 consecutive patients referred for exudative AMD with predominantly occult subfoveal CNV. Based on fluorescein angiography, ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1076/soph.16.2.90.4210
更新日期:2001-06-01 00:00:00
abstract:PURPOSE:To report anterior segment features in unclassified anterior segment dysgenesis with overlapping features of Axenfeld-Rieger syndrome and other developmental anomalies. METHODS:This retrospective study included those with atypical or overlapping features in one or both eyes, which were identified as unclassifi...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820538.2016.1208767
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To evaluate refractive errors in patients with migraine headache and to compare with healthy subjects. MATERIALS AND METHODS:This prospective case-control study includes patients with migraine and age- and sex-matched healthy subjects. Clinical and demographic characteristics of the patients were noted. Detail...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2014.962177
更新日期:2016-01-01 00:00:00
abstract::Age-related macular degeneration (AMD) is a progressive degenerative disease which leads to blindness, affecting the quality of life of millions of Americans. More than 1.75 million individuals in the United States are affected by the advanced form of AMD. The etiological pathway of AMD is not yet fully understood, bu...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2011.577129
更新日期:2011-05-01 00:00:00
abstract::A 50-year-old man presented with uncontrolled erythroclastic glaucoma and recurrent vitreous hemorrhage from a previously irradiated choroidal melanoma. Despite trabeculectomy, intraocular pressure became uncontrolled due to increasing bleeding from the melanoma. The vitreous hemorrhage became voluminous and could not...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820530801894467
更新日期:2008-03-01 00:00:00
abstract::Hereditary ectopia lentis or lens subluxation can occur with and without systemic associations. Significant overlap can be found in the genetic mutations and pathogenesis of subluxated lenses in their isolated forms as well as with associated syndromes. Gene mutations have been identified for lens subluxation associat...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2013.825276
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Vernal keratoconjunctivitis (VKC) is a bilateral multi-factorial disease. The pathogenesis of this disease is not obviously determined, but the role of various inflammatory cytokines has been specified. This study has provided a comparison between the level of interleukin-17 (IL17) in the serum and tears o...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2016.1170162
更新日期:2017-01-01 00:00:00
abstract::Purpose: To evaluate the difference in ellipsoid zone and external limiting membrane (EZ/ELM) restoration after vitrectomy with internal limiting membrane (ILM) peeling in diabetic macular oedema with vitreomacular interface abnormalities (VMA DME) patients using 3 different dyes.Methods: Patients with type 2 diabetes...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2019.1656754
更新日期:2019-01-01 00:00:00
abstract::Guillain-Barre syndrome (GBS) is characterized by an ascending muscle paralysis with progressive loss of muscle stretch reflexes. Annually, approximately 2.4 cases per 100,000 population of GBS are reported. Variant forms do exist. These include the Fisher syndrome, GBS with ophthalmoplegia, Bickerstaff's brainstem en...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820530601006775
更新日期:2006-10-01 00:00:00
abstract::The lacrimal caruncle is a modified cutaneous tissue that contains hair follicles, accessory lacrimal glands, sweat glands, lobules of fat, and sebaceous glands. Due to the nature of tissue, a variety of lesions, both benign and malignant, could arise from this area. Lymphomas of the eye and its adnexa are frequently ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.833260
更新日期:2015-03-01 00:00:00
abstract::Currently, there is no proven drug treatment for dry age-related macular degeneration (AMD). Several different treatment strategies are being investigated, including complement inhibition, neuroprotection, and visual cycle inhibitors, and novel clinical trial endpoints are being explored. Studies have identified genet...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2011.577132
更新日期:2011-05-01 00:00:00
abstract::Subfoveal choroidal neovascularization presents one of the most difficult challenges to vision. No treatment option has yet solved the problem of subretinal hemorrhage and fibrovascular scarring causing permanent photoreceptor degeneration and loss. Limited macular translocation provides a surgical approach to this ch...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820530009039997
更新日期:2000-06-01 00:00:00
abstract:PURPOSE:To assess the effect of low, moderate, and high myopia on the thickness of the retinal nerve fiber layer (RNFL) and Ganglion cell complex (GCC) measured by Spectral Domain Optical Coherence Tomography (SD-OCT) in non-glaucomatous subjects. METHODS:The subjects were divided into three groups: low (n = 81, 35.6%...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2016.1170157
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To characterize anatomical dimensions of a disc notch using novel methods using spectral domain optical coherence tomography (SD-OCT). PARTICIPANTS:All age- and severity-matched glaucoma patients with disc notch (defined as complete loss of neural rim with no residual rim between disc and cup) seen from 2014 t...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2018.1540709
更新日期:2018-01-01 00:00:00
abstract::The onset of post-operative corneal melting and necrotizing scleritis in patients with rheumatoid arthritis and collagen vascular disease who undergo cataract surgery can have devastating ocular and systemic consequences. Even though ocular surface factors such as sicca and surgical trauma are among the important vari...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1076/soph.17.3.124.14786
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:To assess changes in lymphatic vessels, collagen, and elastic fiber structure in excised tissues with dermatochalasis (DC). METHODS:In this prospective histopathological study, 70 upper eyelid skins of 35 patients operated on for dermatochalasis were compared with 10 eyelid skins of 10 patients operated on for...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2017.1282970
更新日期:2018-01-01 00:00:00
abstract::Diabetic retinopathy is one of the most serious complications of chronic diabetes mellitus and is the leading cause of blindness in working-age populations. Large, randomized studies have demonstrated the benefits of systemic and ocular therapy in the prevention and treatment of diabetic retinopathy. The process of an...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2013.859280
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:We aimed to measure peripapillary retinal nerve fiber layer (RNFL) thickness in children with thalassemia major (tha-major), children with iron deficiency anemia (IDA), and children in a healthy control group. MATERIALS AND METHODS:A total of 47 children with tha-major and 22 children with IDA were selected fr...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.839811
更新日期:2014-01-01 00:00:00
abstract::Glaucoma is one of the leading causes of visual impairment worldwide. Classically, clinicians have evaluated patients through a full ophthalmological examination including gonioscopy, measurement of intraocular pressure (IOP), and assessment of the optic nerve. New imaging modalities have further enhanced our ability ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2015.1114858
更新日期:2016-01-01 00:00:00
abstract::Paroxysmal hemicrania is a trigeminal autonomic cephalalgia first described in 1976, characterized by episodic attacks of excruciating unilateral periorbital and temporal stabbing, pulsatile, craw-like, or boring headaches lasting 2 - 30 minutes, accompanied by autonomic features, and alleviated by indomethacin. Parox...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820531003635505
更新日期:2010-01-01 00:00:00
abstract::Macular hole formation is a rare complication of cataract extraction. Although the exact etiology is unclear, macular holes can be classified into pre-existing holes that may not have been visible prior to cataract surgery, early stage macular holes that progressed to a more advanced stage, symptomatic holes following...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1076/soph.17.3.196.14775
更新日期:2002-09-01 00:00:00
abstract::A wide variety of infectious agents are known to cause optic neuropathy. This article will consider the bacteria, spirochetes, fungi, and viruses that most commonly affect the optic nerve. Clinical presentation is variable, but some pathogens often produce a characteristic funduscopic pattern. Diagnosis is usually mad...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1076/soph.17.1.11.10293
更新日期:2002-03-01 00:00:00
abstract::Acute acquired comitant esotropia (AACE) is characterized by a sudden-onset eye misalignment with an equal angle of deviation in all fields of gaze. This form of esotropia is distinct from common forms of childhood esotropia, such as infantile esotropia and accommodative esotropia, in the rapid tempo and typically lat...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820538.2016.1228398
更新日期:2017-01-01 00:00:00
abstract::Many ocular diseases, such as retinitis pigmentosa and age-related macular degeneration, reflect damage to specific cells that are not normally repaired or replaced. Preliminary results of animal studies suggest that these degenerative diseases may be treatable by transplantation of healthy fetal cells. However, obtai...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530590921846
更新日期:2005-01-01 00:00:00