Abstract:
PURPOSE:To assess amniotic membrane retention after amniotic membrane transplant in bullous keratopathy patients and whether there were any corneal structural changes that may hinder further penetrating keratoplasty Methods: A retrospective study including 22 patients who have undergone amniotic membrane transplant from 1 Jan 1998 till 30 Jun 2016. Confocal microscopy and anterior segment optical coherence tomography (ASOCT) were performed to assess the retention of amniotic membrane and to detect any corneal structural changes. The comparison was made with 5 controls who had bullous keratopathy awaiting endothelial keratoplasty. RESULTS:Patients had a mean follow-up of 61 ± 33.7 months. Pain reduction was significant (p < .001) although it did not significantly correlate with the regularity of the superficial, intermediate or basal epithelial layers, nor with the retention of the amniotic membrane. No long-term structural changes that may hinder future penetrating keratoplasty were detected. CONCLUSION:This procedure is a safe and effective long-term treatment for symptomatic bullous keratopathy patients.
journal_name
Semin Ophthalmoljournal_title
Seminars in ophthalmologyauthors
Siu GDJ,Kam KW,Young ALdoi
10.1080/08820538.2019.1620790subject
Has Abstractpub_date
2019-01-01 00:00:00pages
163-167issue
3eissn
0882-0538issn
1744-5205journal_volume
34pub_type
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