The Boston Ocular Surface Prosthesis as a novel drug delivery system for bevacizumab.

Abstract:

:Corneal neovascularization causes deterioration of visual acuity and increases surface irregularities. Various techniques have been employed to help control the progression of corneal neovascularization; bevacizumab is a medication that targets the specific pathway of corneal neovascularization. The Boston Ocular Surface Prosthesis (BOSP) is a large diameter contact lens that aids in maintaining corneal surface integrity and may serve as a delivery system for topical bevacizumab. This paper reviews five patients who were treated with topical bevacizumab in their BOSP. All patients demonstrated improvement in their visual acuity and clinical exam. No adverse reactions were noted.

journal_name

Semin Ophthalmol

authors

Lim M,Jacobs DS,Rosenthal P,Carrasquillo KG

doi

10.1080/08820530902802013

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

149-55

issue

3

eissn

0882-0538

issn

1744-5205

pii

911108966

journal_volume

24

pub_type

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