Retinal Nerve Fiber Layer Thickness Alterations after Electroconvulsive Therapy in Patients with Mental Illness.

Abstract:

BACKGROUND:We hypothesized that the ongoing neurotrophic effects of electroconvulsive therapy (ECT) might be detected in the retinal nerve fiber layer (RNFL) using optical coherence tomography (OCT). METHODS:This study was conducted using a prospective design. The RNFL thickness alterations of 18 psychiatric patients undergoing ECT were assessed using OCT. The results were compared with the RNFL thicknesses of 18 age and gender-matched healthy controls. RESULTS:In the left eye, the average RNFL (p = 0.025), superior quadrant (p = 0.029), and nasal quadrant (p = 0.021) thicknesses were significantly increased after the last ECT treatment. In contrast to the right eye, the basal left-eye superior RNFL thickness (p = 0.038) and inferior quadrant (p = 0.007) thicknesses were significantly lower in the patients than in the healthy controls. CONCLUSION:Here, we have revealed a significant lateralized influence of ECT on the left-eye RNFL. However, larger case series should be conducted before interpreting our current findings.

journal_name

Semin Ophthalmol

authors

Ucar D,Yıldız N,Hepokur M,Baltu F,Guliyev E,Emul M,Sarıcı AM

doi

10.1080/08820538.2018.1538419

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

852-857

issue

7-8

eissn

0882-0538

issn

1744-5205

journal_volume

33

pub_type

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