GQ1b antibody testing in Guillain-Barre syndrome and variants.

Abstract:

:Guillain-Barre syndrome (GBS) is characterized by an ascending muscle paralysis with progressive loss of muscle stretch reflexes. Annually, approximately 2.4 cases per 100,000 population of GBS are reported. Variant forms do exist. These include the Fisher syndrome, GBS with ophthalmoplegia, Bickerstaff's brainstem encephalitis (BBE), and acute ophthalmoparesis without ataxia. In the last 15 years, attention has been directed towards the association of the GQ1b IgG antibody and several GBS variants, particularly the Fisher syndrome and those associated with ophthalmoparesis. We present three cases of GBS variants. All three cases had associated ophthalmoplegia but only one of the three had a positive GQ1b antibody association.

journal_name

Semin Ophthalmol

authors

Chaudhry F,Gee KE,Vaphiades MS,Biller J,Jay W

doi

10.1080/08820530601006775

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

223-7

issue

4

eissn

0882-0538

issn

1744-5205

pii

P28VM233511N22Q1

journal_volume

21

pub_type

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