Abstract:
BACKGROUND:Adipose-derived stromal cells (ADSCs) may play a pivotal role by differentiating into multilineage cells or by secreting growth factors or cytokines in cell-assisted lipotransfer, which participates in adipose tissue regeneration. The angiogenic potential of various ADSCs from different anatomical regions remains uncertain. OBJECTIVES:The authors sought to offer appropriate choices of sources of adipose-derived stromal cells for cell-assisted lipotransfer and tissue engineering. METHODS:ADSCs were harvested from subcutaneous adipose depots in the abdomen and thighs. The expression of adipocyte-specific markers was evaluated, and Oil Red O staining was performed to assess the capacity for adipogenic differentiation. Angiogenic differentiation potential was evaluated by detecting the expression of vascular endothelial growth factor, vascular endothelial growth factor 2, and CD31. A tube formation assay was also performed to analyze the angiogenic differentiation capacity. RESULTS:ADSCs from the thigh showed more significant angiogenic and adipogenic potential. More lipogenesis was identified in ADSCs from the thigh, and this was accompanied by the enhancement of adipocyte markers. Angiogenesis was more vigorous in the thigh-derived stromal cells, and ADSCs from the thigh depot showed more junctions and longer tubule formation on Matrigel in vitro. CONCLUSIONS:Thigh-derived ADSCs exhibited greater capacity for adipogenic and angiogenic differentiation and would be a better option for cell-assisted lipotransfer and tissue engineering.
journal_name
Aesthet Surg Jjournal_title
Aesthetic surgery journalauthors
Li W,Zhang Y,Chen C,Tian W,Wang Hdoi
10.1093/asj/sjy252subject
Has Abstractpub_date
2019-04-08 00:00:00pages
NP140-NP149issue
5eissn
1090-820Xissn
1527-330Xpii
5144675journal_volume
39pub_type
杂志文章abstract:BACKGROUND:Given the wide application of autologous fat grafting, a new emphasis on fat processing techniques has emerged in an effort to limit unpredictable degrees of resorption often seen with this procedure. With the growing interest in regenerative medicine, approaches to supplement fat grafts with adipose-derived...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13487371
更新日期:2013-07-01 00:00:00
abstract::The author contends that an important reason to choose the endoscopic transaxillary technique for breast augmentation is the avoidance of scars on the aesthetic unit of the breast. Other advantages include increased precision in creating the pocket, providing a well-shaped inframammary fold; reduced bleeding; less pos...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2003.10.004
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:In order for aesthetic surgery to participate in the movement toward evidence-based medicine, a system that quantifies aesthetic outcomes must be developed based on reliable and reproducible data. Previous studies have investigated the attractiveness of averaged (or composite) faces. Data has shown that thes...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X10369370
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Several studies have attempted to define the dimensions of an aesthetically pleasing eyebrow. However, these dimensions represent the views of plastic surgeons and cosmetologists, not necessarily the general public. We hypothesized that many patients who present to their plastic surgeon for periorbital rejuv...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2005.05.002
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Many strategies have been developed to lower the high complications rate associated with a full abdominoplasty. The dissection technique may have a role to achieve this goal. OBJECTIVES:The present study compares two different dissection techniques to perform a full abdominoplasty with Scarpa fascia preserv...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa428
更新日期:2021-01-06 00:00:00
abstract:Background:Improvement in the retention rate of transplanted fat is currently a topic of interest. The retention of transplanted fat relies heavily on the reestablishment of blood supply and the function of the adipose-derived stem cells (ADSCs), which may both be impeded by mechanical force. However, the effect of mec...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy104
更新日期:2018-08-16 00:00:00
abstract:BACKGROUND:Facial aging is a complicated process that includes volume loss and soft tissue descent. This study provides quantitative 3-dimensional (3D) data on the long-term effect of vertical vector deep-plane rhytidectomy on restoring volume to the midface. OBJECTIVE:To determine if primary vertical vector deep-plan...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sju171
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The efficacy of adipose-derived stem cells (ASCs) to improve wound healing has been extensively investigated. Unfortunately, no consistent reports have described significant improvements in healing time or outcomes in large-scale clinical trials utilizing human ASCs. Primarily, these studies examined undiffe...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjz071
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Following primary rhinoplasty, the nasal tip may become wider on front view, possibly due to splaying of the lateral crura. OBJECTIVES:The authors describe a technique, the "supratip-plasty," to create an all-cartilaginous supratip that resists splaying and postoperative broadening of the nasal tip complex....
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13515269
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:"Medical tourism" has gained popularity over the past few decades. This is particularly common with patients seeking elective cosmetic surgery in the developing world. However, the risk of severe and unusual infectious complications appears to be higher than for patients undergoing similar procedures in the ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjw047
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Large area local anesthesia (LALA) has been recommended for decreasing localized pain and shortening discharge time after breast augmentation surgery. However, quantifiable, objective outcome data for evaluation of the effectiveness of LALA in aesthetic plastic surgery procedures have not yet been reported. ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2004.06.003
更新日期:2004-09-01 00:00:00
abstract::Abdominoplasty, the removal of excess skin combined with muscle plication of a patient's abdominal region, can yield pleasing postoperative results alone, but adding significant concurrent circumferential abdominal liposuction to the procedure can dramatically improve the overall shape and contour of the final result....
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X11412487
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Adipose and adipose derived regenerative cells (ADRCs) play an increasing role in androgenetic alopecia. OBJECTIVES:The authors sought to evaluate the safety and feasibility of fat grafts enriched with ADRCs in early androgenetic alopecia. METHODS:Seventy-one patients were treated: 16 with Puregraft fat an...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa037
更新日期:2020-05-16 00:00:00
abstract:BACKGROUND:The American Society for Aesthetic Plastic Surgery (ASAPS) sponsors an annual conference that promotes education, advocacy, and care. There, researchers deliver abstracts as podium and poster presentations. Subsequently, ASAPS encourages submitting these research findings for publication. Yet, many never bec...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjw097
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Women tend to develop more and deeper wrinkles in the perioral region than men. Although much is known about the complex mechanisms involved in skin aging, previous studies have described histologic differences between men and women with respect to skin aging only incidentally and have not investigated the p...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2009.08.018
更新日期:2009-11-01 00:00:00
abstract:Background:Low satisfaction rates and severe complications are two major limitations for temporal hollowing augmentation using autologous fat grafting. Despite fat compartments in temporal region have been reported, its clinical applied anatomy for fat grafting have not been the subject of studies that show its benefit...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjw257
更新日期:2017-09-01 00:00:00
abstract::The author demonstrates his method of achieving optimal contour in the aging neck. Primary features of the technique are horizontal cuts in the vertical bands of the platysma muscle combined with a corset Z-plasty medial suture and bilateral rein plication suture. This combined procedure, which effectively lifts the s...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1016/j.asj.2007.12.006
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Traditionally, repair of the midline fascial defect has been performed with interrupted or running permanent sutures during abdominoplasty. Barbed suture devices, however, eliminate the need for knot tying and potentially are equally effective at maintaining the repair while allowing for faster deployment an...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X11415242
更新日期:2011-08-01 00:00:00
abstract::Rhinoplasty utilizes cartilage harvested from the nasal septum as autologous graft material. Traditional dogma espouses preservation of the "L-strut" of dorsal and caudal septum, which is less resistant to axial loading than virgin septum. Considering the 90° angle between dorsal and caudal limbs, the traditional L-st...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1093/asj/sjy301
更新日期:2019-11-13 00:00:00
abstract:BACKGROUND:Masculinization of the face is a common finding in facelift patients. It is attributed to deflation and decent of the midface-jowls coupled with skin laxity. Fullness is evident lateral to the jowl in small percentage due to prominent buccal fat pad. OBJECTIVES:To examine the anatomy of the buccal fat pad, ...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa015
更新日期:2020-01-22 00:00:00
abstract:Background:Achieving aesthetic results with forehead augmentation procedures remains challenging. We have developed a method of integrated forehead and temporal augmentation using a three-dimensional (3D) printing-assisted methyl methacrylate implant. Objectives:The study objective was to assess the importance of comb...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy075
更新日期:2018-10-15 00:00:00
abstract:BACKGROUND:Injections are associated with a certain amount of pain, the tolerance of which can vary between individuals. With regard to noninvasive pain control techniques in subcutaneous injections, few studies with adequate levels of evidence and design quality exist to support any specific analgesic method. OBJECTI...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,随机对照试验
doi:10.1093/asj/sjz380
更新日期:2021-01-01 00:00:00
abstract::Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL)-a new category of anaplastic large cell lymphoma associated with textured breast implants-has a distinct variation in incidence and is especially rare in Asia. We report the first case of BIA-ALCL in Korea and present its histological and genetic char...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjaa398
更新日期:2020-12-26 00:00:00
abstract:BACKGROUND:Although the anatomy of the individual pectoralis major and minor muscles has been described previously, never before has the anatomic relationship between these muscles been investigated. OBJECTIVE:The authors identify the anatomic relationship of the costal origins of the pectoralis major and minor muscle...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X13519643
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The suspension of orbicularis oculi during lower blepharoplasty presents a logical surgical addition for further support of the lid, as well as further improvement to its contour profile. It has traditionally been performed as an extension of the skin-muscle flap procedure, but more recently, and aggressivel...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjw052
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Fat necrosis is a frequent complication (up to 62.5%) of microsurgical breast reconstruction using the deep inferior epigastric perforator (DIEP) flap. This could have important clinical and psychological repercussions, deteriorating the results and increasing reconstruction costs. OBJECTIVES:The aim of thi...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy256
更新日期:2019-03-14 00:00:00
abstract:BACKGROUND:Body contouring that involves abdominoplasty and/or liposuction is a common cosmetic surgery procedure. Although single-staged lipoabdominoplasty has gained popularity, safety concerns remain. OBJECTIVES:The authors compared abdominal flap perfusion and overall complication rates for traditional abdominopla...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1177/1090820X14532286
更新日期:2014-07-01 00:00:00
abstract::Recent technical advances in fat grafting and the development of surgical devices such as liposuction cannulae have made fat grafting a relatively safe and effective procedure. However, new guidelines issued by the American Society of Plastic Surgeons in 2009 announced that fat grafting to the breast is not a strongly...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1177/1090820X10373063
更新日期:2010-05-01 00:00:00
abstract::Paradigms in the treatment of aging have evolved to address volume loss as a central and primary hallmark of the aging face. The concept of "composite volumization" was recently proposed by Dr. Z. Paul Lorenc to describe the effect of Radiesse (Merz Aesthetics, Inc., Raleigh, NC), when placed on bone in the supraperio...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章
doi:10.1093/asj/sjy026
更新日期:2018-04-06 00:00:00
abstract::Although the principles of burn management are still primarily focused on survival, as advances are realized in resuscitation, nutrition, and wound management, the functional and aesthetic outcomes following burn injury have become increasingly important. Acellular dermal matrix materials, which allow surgeons to mini...
journal_title:Aesthetic surgery journal
pub_type: 杂志文章,评审
doi:10.1177/1090820X11418202
更新日期:2011-09-01 00:00:00