Effect of the new synthetic vitamin E derivative ETS-GS on radiation enterocolitis symptoms in a rat model.

abstract：:Elongator protein 3 (ELP3), the catalytic subunit of the elongator complex of RNA polymerase II, is involved in various functions, including transcriptional elongation, chromatin modification and cytoskeletal regulation. In this study, ELP3 expression was immunohistochemically examined in normal uterus tissue and uter...

journal_title：Oncology letters

authors： Wang Y,Ikeda JI,Rahadiani N,Mamat S,Ueda Y,Tian T,Enomoto T,Kimura T,Aozasa K,Morii E

更新日期：2012-01-01 00:00:00

abstract：:Although it is established as a marker of cancer-associated fibroblasts, the expression of fibroblast activation protein (FAP) is not restricted to stromal cells; its expression in multiple types of tumor cell and its pro-tumor functions have been reported. However, the role of FAP in angiogenesis in osteosarcoma rema...

journal_title：Oncology letters

authors： Zeng C,Wen M,Liu X

更新日期：2018-04-01 00:00:00

abstract：:Evaluation of carcinogenic substances from the environment is a challenge for scientists. Recently, a novel approach based on 10 key characteristics of human carcinogens classified by the International Agency for Research on Cancer (IARC) has emerged. Carcinogenesis depends on different mechanisms and factors, includi...

journal_title：Oncology letters

authors： Calaf GM,Ponce-Cusi R,Aguayo F,Muñoz JP,Bleak TC

更新日期：2020-07-01 00:00:00

abstract：:Solitary fibrous tumors (SFTs) represent a rare type of soft tissue tumor. Extrathoracic SFTs (ESFTs) in the soft tissues of the abdominopelvic cavity are extremely rare. Between January 2002 and January 2013, 10 patients were identified with abdominopelvic SFTs at the Northern Jiangsu People's Hospital. The clinicopa...

journal_title：Oncology letters

authors： Wang H,Chen P,Zhao W,Shi L,Gu X,Xu Q

更新日期：2014-04-01 00:00:00

abstract：:Expression of copper-transporting P-type adenosine triphosphatase A (ATP7A) is reportedly associated with platinum drug resistance in various types of solid tumors. However, the impact of ATP7A expression on platinum drug resistance in non-small cell lung cancer (NSCLC) has yet to be adequately elucidated. In vitro ci...

journal_title：Oncology letters

authors： Inoue Y,Matsumoto H,Yamada S,Kawai K,Suemizu H,Gika M,Takanami I,Iwazaki M,Nakamura M

更新日期：2010-09-01 00:00:00

abstract：:The present study aimed to investigate the effects of silencing RIP1 by small interfering RNA (siRNA) on the biological behavior of the LoVo human colorectal carcinoma cell line and to provide evidence for the feasibility of colorectal cancer gene therapy. LoVo cells were divided into the RIP1 siRNA group, the blank c...

journal_title：Oncology letters

authors： You HX,Zhou YH,Tan SY,She TH

更新日期：2014-06-01 00:00:00

abstract：:No evidence currently exists to demonstrate the prognostic value of serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) in patients with unresectable colorectal cancer liver metastases (CRLM). Therefore, we retrospectively investigated the correlation between serum CEA and CA19-9 levels and ove...

journal_title：Oncology letters

authors： Mitsuyama Y,Shiba H,Haruki K,Fujiwara Y,Furukawa K,Iida T,Hayashi T,Ogawa M,Ishida Y,Misawa T,Kashiwagi H,Yanaga K

更新日期：2012-04-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/ol.2017.5668.]. ...

journal_title：Oncology letters

authors： Lee J,Kim DS,Lee HS,Choi SI,Cho YG

更新日期：2017-11-01 00:00:00

abstract：:Numerous studies have suggested that microRNAs (miRNAs) potently affect hepatocarcinogenesis. However, the miRNA expression profiling in patients with hepatocellular carcinoma (HCC) of familial aggregation and hepatitis B virus (HBV) infection has not been elucidated. In the present study, the plasma miRNA expression ...

journal_title：Oncology letters

authors： Zhang EL,Gu J,Zhang ZY,Dong KS,Liang BY,Huang ZY

更新日期：2017-07-01 00:00:00

abstract：:Previous studies have demonstrated that the chronic administration of valproic acid (VPA) suppresses angiogenesis in vivo; however, the mechanisms implicated in VPA-induced autophagy remain unclear. The current study aimed to assess VPA-induced autophagy in three prostate cancer cell lines (PC3, DU145 and LNCaP), in a...

journal_title：Oncology letters

authors： Xia Q,Zheng Y,Jiang W,Huang Z,Wang M,Rodriguez R,Jin X

更新日期：2016-09-01 00:00:00

abstract：:The present study sought to characterize the role of macrophage inflammatory protein-3α (MIP-3α) in non-small cell lung cancer (NSCLC) patients with early recurrence or metastasis after primary pulmonary resection. Follow-up examinations were conducted for 203 NSCLC patients with primary pulmonary resection for two ye...

journal_title：Oncology letters

authors： Zhang X,Meng A,Wang H,Yan X

更新日期：2014-08-01 00:00:00

abstract：:Cisplatin resistance has been a major factor limiting its clinical use as a chemotherapy drug. The present study aimed to investigate whether SET and MYND domain-containing protein 3 (SMYD3), a histone methyltransferase closely associated with tumors can affect the sensitivity of tumors to cisplatin chemotherapy. Real...

journal_title：Oncology letters

authors： Wang L,Xu ML,Wang C,Dong QQ,Miao Z,Chen XY,Wang N,He HP,Zhang TC,Luo XG

更新日期：2020-05-01 00:00:00

abstract：:The chemokine CXCL10 and its receptor CXCR3 have been demonstrated to be implicated in cancer cell proliferation and metastasis. CXCR3 has three splice variants: CXCR3A, CXCR3B and CXCR3-alt. CXCR3A and B serve multiple roles in the growth and invasiveness of a number of cancer types. However, the roles of CXCR3 isofo...

journal_title：Oncology letters

authors： Nozaki E,Kobayashi T,Ohnishi H,Ohtsuka K,Masaki T,Watanabe T,Sugiyama M

更新日期：2020-03-01 00:00:00

abstract：:Tuberous sclerosis complex (TSC) is an autosomal dominant disease involving multiple organs, but there are a limited number of reports on family TSC. In the present report, a case of a 52-year-old female with a familial genetic TSC, associated with bilateral giant renal angiomyolipoma, was described. The mother, secon...

journal_title：Oncology letters

authors： Wang L,Ni D,Zhong L,Wang J

更新日期：2017-12-01 00:00:00

abstract：:Radiofrequency ablation has become an increasingly common therapeutic technique for patients with hepatocellular carcinoma or metastatic liver tumors. However, reports on the effect of percutaneous radiofrequency ablation (PRFA) on circulating tumor cells (CTCs) are limited. The present study aimed to further investig...

journal_title：Oncology letters

authors： Li Y,Huang N,Wang C,Ma H,Zhou M,Lin L,Huang Z,Sun L,Shi M,Liao W

更新日期：2018-09-01 00:00:00

abstract：:This study aimed to determine whether manipulation of the microRNA-200 (miR-200) family could influence colon adenocarcinoma cell behavior. The miR-200 family has a significant role in tumor suppression and functions as an oncogene. In vitro studies on gain and loss of function with small interfering RNA demonstrated ...

journal_title：Oncology letters

authors： Carter JV,O'Brien SJ,Burton JF,Oxford BG,Stephen V,Hallion J,Bishop C,Galbraith NJ,Eichenberger MR,Sarojini H,Hattab E,Galandiuk S

更新日期：2019-10-01 00:00:00

abstract：:Toll-like receptor-9 (TLR9) is a member of the innate immune system and recognizes bacterial and vertebrate DNA in cells. In addition to being expressed in cells of the immune system, it is widely expressed in various types of human cancer, including prostate cancer. We have previously demonstrated that synthetic TLR9...

journal_title：Oncology letters

authors： Väisänen MR,Jukkola-Vuorinen A,Vuopala KS,Selander KS,Vaarala MH

更新日期：2013-05-01 00:00:00

abstract：:Radical cystectomy, as the most common surgical treatment for patients with invasive bladder cancer (IBC) complicated by peritoneal metastasis, is usually accompanied by a urinary diversion procedure. In this study, we evaluated the improved tubeless cutaneous ureterostomy technique by comparing the resulting clinical...

journal_title：Oncology letters

authors： Liu Z,Tian Q,Xia S,Yin H,Yao D,Xiu Y

更新日期：2016-02-01 00:00:00

abstract：:Breast cancer is the most prevalent cancer among women, and diagnosis and treatment represent a substantial challenge due to the lack of adequate molecular targets. It has been shown that long noncoding RNAs (lncRNAs) serve pivotal roles in regulating gene expression in tumors. The roles of long intervening noncoding ...

journal_title：Oncology letters

authors： Zhu Q,Li Y,Dong X,Yang Y,Wang H,Guo S

更新日期：2020-01-01 00:00:00

abstract：:The present study investigated the correlations of the Tspan-1 gene expression with the clinical characteristics and survival prognoses of patients with advanced gastric cancer. A total of 150 patients with advanced gastric cancer were enrolled in the present study, of whom 84 were at stage II and 66 were at stage III...

journal_title：Oncology letters

authors： Cai Y,Zheng M,Zhao Z,Huang H,Fu W,Xu X

更新日期：2017-09-01 00:00:00

abstract：:Trefoil factor 2 (TFF2) plays a protective role in gastric mucosa and may be involved in the progression of gastric cancer, but the detailed functions and underlying molecular mechanisms are not clear. The present study used a combination of clinical observations and molecular methods to investigate the correlation be...

journal_title：Oncology letters

authors： Jiang P,Yu G,Zhang Y,Xiang Y,Zhu Z,Feng W,Lee W,Zhang Y

更新日期：2014-05-01 00:00:00

abstract：:Wiskott-Aldrich syndrome protein family member 3 (WASF3) is required for invasion and metastasis in different cancer cell types, and has been demonstrated to possess prognostic value in various types of human cancer. However, to the best of our knowledge, the expression profile of WASF3 and its correlations with the c...

journal_title：Oncology letters

authors： Wu J,Wang GC,Chen XJ,Xue ZR

更新日期：2014-09-01 00:00:00

abstract：:Ku80, a subunit of the heterodymeric Ku protein, is clearly implicated in nonhomologous end joining DNA repair, chemoresistance and radioresistance in malignant tumors. In the present study, the clinicopathological significance of Ku80 in esophageal squamous cell carcinoma (ESCC) was investigated. The expression level...

journal_title：Oncology letters

authors： Wang S,Wang Z,Yang YU,Shi MO,Sun Z

更新日期：2015-11-01 00:00:00

abstract：:The present case report describes the infrequent coexistence of squamous cell transformation and the epidermal growth factor receptor (EGFR) T790M mutation as resistance mechanisms to first line treatment with tyrosine kinase inhibitors. The patient was a 44-year-old female, diagnosed with a primitive advanced lung ad...

journal_title：Oncology letters

authors： Bruno R,Proietti A,Alì G,Puppo G,Ribechini A,Chella A,Fontanini G

更新日期：2017-11-01 00:00:00

abstract：:Differences in inflammatory factors IL-6 and miR-1271 expression levels between elderly and young gastric cancer patients were investigated. A retrospective analysis of 146 cases of gastric cancer tissue and normal fresh tissue specimens diagnosed in The First Hospital of Lanzhou University from January 2013 to Januar...

journal_title：Oncology letters

authors： Liu S,Zhou Y,Zhao L,Wang J,Ji R,Wang Y,Wu J,Yan X

更新日期：2019-06-01 00:00:00

abstract：:Inflammatory myofibroblastic tumor (IMT) is a rare type of mesenchymal tumor, which may affect various organs. The preferential site for IMT in the genitourinary system is the urinary bladder, while the presence of IMT in the kidney, and particularly in the renal pelvis, is rare. In the present report, the case of a 4...

journal_title：Oncology letters

authors： Wu S,Xu R,Zhao H,Zhu X,Zhang L,Zhao X

更新日期：2015-12-01 00:00:00

abstract：:Recent studies have shown that a small subpopulation of stem-like cancer cells within most solid tumors are responsible for the malignancy of aggressive cancer cells, including tumorigenicity and relapse of solid tumors. These tumor cells may be enriched and maintained in vitro in the presence of growth factors (GFs),...

journal_title：Oncology letters

authors： Kim J,Jung J,Lee SJ,Lee JS,Park MJ

更新日期：2012-03-01 00:00:00

abstract：:The present study aimed to investigate the anticancer effect of aloe-emodin, an anthraquinone compound present in the leaves of Aloe vera, on two human colon carcinoma cell lines, DLD-1 and WiDr. Colon carcinoma cells were treated with various concentrations of aloe-emodin for different durations. Cell viability was m...

journal_title：Oncology letters

authors： Lin KY,Uen YH

更新日期：2010-05-01 00:00:00

abstract：:MicroRNAs (miRNAs/miRs) are identified to serve key functions in the progression of various tumors. miR-214 is aberrantly expressed in various types of cancer. In the present study, the function of miR-214 and its feasibility as a potential non-invasive biomarker for patients with prostate cancer (PCa) in a hyperplasi...

journal_title：Oncology letters

authors： Fang Y,Qiu J,Jiang ZB,Xu SR,Zhou ZH,He RL

更新日期：2019-01-01 00:00:00

abstract：:The aim of the present study was to determine the impact of obesity on radiation-induced gastrointestinal (GI) and genitourinary (GU) toxicity. The cases of 54 patients with prostate cancer, treated with three-dimensional conformal radiation therapy (RT), were reviewed. For each patient, the body mass index (BMI), dis...

journal_title：Oncology letters

authors： Doi H,Ishimaru F,Tanooka M,Inoue H,Odawara S,Takada Y,Niwa Y,Fujiwara M,Kamikonya N,Yamamoto S,Hirota S

更新日期：2014-01-01 00:00:00