Evaluation of the improved tubeless cutaneous ureterostomy technique following radical cystectomy in cases of invasive bladder cancer complicated by peritoneal metastasis.

Abstract:

:Radical cystectomy, as the most common surgical treatment for patients with invasive bladder cancer (IBC) complicated by peritoneal metastasis, is usually accompanied by a urinary diversion procedure. In this study, we evaluated the improved tubeless cutaneous ureterostomy technique by comparing the resulting clinical effects with either a traditional ureterostomy and an ileal conduit urinary diversion. Clinical data from 85 patients who underwent 1 of the 3 procedures between April 2012 and April 2015 were analyzed retrospectively. In total, 30 patients underwent improved tubeless cutaneous ureterostomy, 28 patients underwent a traditional cutaneous ureterostomy and 27 underwent an ileal conduit urinary diversion following radical cystectomy. The incidence of complications, including stoma infection, nipple atrophy, terminal necrosis, urine leakage, external orifice stenosis, uronephrosis and ureterectasia in the group of patients treated with the improved tubeless ureterostomy technique was significantly lower than that of the patients in the other 2 groups, and the difference was statistically significant (P<0.05). In addition, the duration of the surgery, intra-operative bleeding, the duration of the hospitalization period and the time to extubation in the patients treated with the improved tubeless ureterostomy technique were significantly decreased (P<0.05) compared with the patients in the other 2 groups. Finally, the health-related quality of life of the patients treated with the improved tubeless ureterostomy technique was significantly higher (P<0.05) than that of the patients in the other 2 groups. The findings of our study demonstrated that the use of the improved tubeless cutaneous ureterostomy technique following radical cystectomy in patients with IBC complicated by peritoneal metastasis resulted in improved clinical effects. Thus, improved tubeless cutaneous ureterostomy may be a promising alternative for enhancing the quality of life of patients with IBC.

journal_name

Oncol Lett

journal_title

Oncology letters

authors

Liu Z,Tian Q,Xia S,Yin H,Yao D,Xiu Y

doi

10.3892/ol.2015.4045

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

1401-1405

issue

2

eissn

1792-1074

issn

1792-1082

pii

OL-0-0-4045

journal_volume

11

pub_type

杂志文章
  • miR-29a activates Hes1 by targeting Nfia in esophageal carcinoma cell line TE-1.

    abstract::MicroRNA (miR)-29a has been associated with carcinogenesis in humans; however, its functional significance in esophageal squamous cell carcinoma (ESCC) is yet to be determined. In the present study, the expression of miR-29a was markedly downregulated in ESCC tissue and the ESCC TE-1 cell line, compared with normal es...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2678

    authors: Liu C,Duan P,Li B,Huang C,Jing Y,Yan W

    更新日期:2015-01-01 00:00:00

  • MAP30 promotes apoptosis of U251 and U87 cells by suppressing the LGR5 and Wnt/β-catenin signaling pathway, and enhancing Smac expression.

    abstract::Significant antitumor activity of Momordica anti-human immunodeficiency virus protein of 30 kDa (MAP30) purified from Momordica charantia has been the subject of previous research. However, the effective mechanism of MAP30 on malignant glioma cells has not yet been clarified. The aim of the present study was to invest...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8073

    authors: Jiang Y,Miao J,Wang D,Zhou J,Liu B,Jiao F,Liang J,Wang Y,Fan C,Zhang Q

    更新日期:2018-04-01 00:00:00

  • Location of NLS-RARα protein in NB4 cell and nude mice.

    abstract::In the majority of acute promyelocytic leukemia (APL) cases, translocons produce a promyelocytic leukemia protein-retinoic acid receptor α (PML-RARα) fusion gene. Studies have reported that neutrophil elastase (NE) cleaves bcr-1-derived PML-RAα in early myeloid cells, leaving only the nuclear localization signal (NLS)...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.5706

    authors: Wang H,Yang R,Zhong L,Zhu XY,Ma PP,Yang XQ,Jiang KL,Liu BZ

    更新日期:2017-04-01 00:00:00

  • Evaluation of photodynamic therapy in adhesion protein expression.

    abstract::Photodynamic therapy (PDT) is a treatment modality that has clinical applications in both non-neoplastic and neoplastic diseases. PDT involves a light-sensitive compound (photosensitizer), light and molecular oxygen. This procedure may lead to several different cellular responses, including cell death. Alterations in ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2149

    authors: Pacheco-Soares C,Maftou-Costa M,DA Cunha Menezes Costa CG,DE Siqueira Silva AC,Moraes KC

    更新日期:2014-08-01 00:00:00

  • Proteasome inhibitor MG132 suppresses pancreatic ductal adenocarcinoma-cell migration by increasing ESE3 expression.

    abstract::The clinical significance of the proteasome inhibitor MG132 has been examined in numerous human cancer types; however, its influence on the metastasis and progression of pancreatic cancer is yet to be determined. In the present study, the effect of MG132 treatment on pancreatic ductal adenocarcinoma (PDAC) cell lines ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.11157

    authors: Jin F,Xiao D,Zhao T,Yu M

    更新日期:2020-01-01 00:00:00

  • Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer.

    abstract::Metastasis-associated in colon cancer-1 (MACC1) is a gene that has been newly identified by a genome-wide search for differentially expressed genes in human colon cancer tissues, metastases and normal tissues. MACC1 exerts an important role in colon cancer metastasis through upregulation of the c-Met proto-oncogene. T...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.2984

    authors: Li H,Zhang H,Zhao S,Shi Y,Yao J,Zhang Y,Guo H,Liu X

    更新日期:2015-05-01 00:00:00

  • HIF-1α promotes ZEB1 expression and EMT in a human bladder cancer lung metastasis animal model.

    abstract::Lung is one of the most common sites for bladder cancer to metastasize. Although the involvement of the epithelial-to-mesenchymal transition (EMT) in bladder cancer progression has been established, the mechanism of EMT induction remains unclear. In order to investigate this, T24-parental (P) and T24-lung (L) bladder ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.7764

    authors: Zhu J,Huang Z,Zhang M,Wang W,Liang H,Zeng J,Wu K,Wang X,Hsieh JT,Guo P,Fan J

    更新日期:2018-03-01 00:00:00

  • Wide local excision and reconstructive surgery of desmoid tumour of the crus (Case report).

    abstract::Extra-abdominal desmoid tumour is a rare type of tumour which is conventionally treated with wide local excision. However, wide local excision usually causes irreparable damage to the limbs. Nevertheless, few patients have been subjected to wide local excision and reconstructive surgery in a single procedure. A 52-yea...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2012.766

    authors: Cao C,Zou J,Wu C,Bao Z,Yang H

    更新日期:2012-09-01 00:00:00

  • Association between SET expression and glioblastoma cell apoptosis and proliferation.

    abstract::Glioblastoma multiforme (GBM) was one of the first cancer types systematically studied at a genomic and transcriptomic level due to its high incidence and aggressivity; however, the detailed mechanism remains unclear, even though it is known that numerous cytokines are involved in the occurrence and development of GBM...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.4951

    authors: He K,Shi L,Jiang T,Li Q,Chen Y,Meng C

    更新日期:2016-10-01 00:00:00

  • Human papillomavirus infection induces NF-κB activation in cervical cancer: A comparison with penile cancer.

    abstract::This study aimed to determine the relationship between human papillomavirus (HPV) and nuclear factor-κB (NF-κB) in cervical cancer using 62 tissues of cervical cancer, and to compare the findings to penile cancer. HPV-DNA integration is a crucial factor for malignant transformation in cervical cancer and can be identi...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2010.207

    authors: Senba M,Buziba N,Mori N,Fujita S,Morimoto K,Wada A,Toriyama K

    更新日期:2011-01-01 00:00:00

  • Clinical experience with nanoparticle albumin-bound paclitaxel, a novel taxane anticancer agent, and management of adverse events in females with breast cancer.

    abstract::Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) is currently approved in Japan for treatment of breast cancer. However, apart from phase I clinical trials, data regarding Japanese patients are scant. In the present study, the efficacy and safety of nab-paclitaxel therapy were retrospectively analyzed in 22 pati...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.2954

    authors: Takashima S,Kiyoto S,Takahashi M,Hara F,Aogi K,Ohsumi S,Mukai R,Fujita Y

    更新日期:2015-04-01 00:00:00

  • miR-26a suppresses osteosarcoma migration and invasion by directly targeting HMGA1.

    abstract::Osteosarcoma (OS) is identified as the most commonly diagnosed malignant cancer of bone, and has approximately three million new cases annually. miR-26a plays an important role in the development of various types of cancer. We investigated whether miR-26a can regulate the migration and invasion of OS by targeting high...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8359

    authors: Liu J,Mi B,Wang Y,Shi C,Mi X,Lu Y,Yu P

    更新日期:2018-06-01 00:00:00

  • Association of chemokine and chemokine receptor expression with the invasion and metastasis of lung carcinoma.

    abstract::The chemokine system has been reported to be utilized and manipulated by tumor cells in order to promote local tumor growth and distant dissemination. The present study aimed to investigate the expression of three chemokine ligand-receptor axes in lung carcinoma tissues. Tumor and healthy normal tissue samples were ob...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.3402

    authors: Liu Y,Wu BQ,Geng H,Xu ML,Zhong HH

    更新日期:2015-09-01 00:00:00

  • miR-449c inhibits migration and invasion of gastric cancer cells by targeting PFKFB3.

    abstract::microRNAs (miRNAs) are important regulators in the development and progression of human gastric cancer (GC). However, the expression and biological function of miR-449c in GC remains unknown. In the present study, miR-449c was demonstrated to be downregulated in GC tissues and cell lines compared with normal. Decrease...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8609

    authors: Chen X,Wang A,Yue X

    更新日期:2018-07-01 00:00:00

  • MicroRNA-186 targets Yes-associated protein 1 to inhibit Hippo signaling and tumorigenesis in hepatocellular carcinoma.

    abstract::Liver cancer, particularly hepatocellular carcinoma (HCC), is one of leading causes of cancer-related mortality worldwide. Upregulation of the evolutionary conserved Hippo signaling pathway has been observed in HCC patients, and Yes-associated protein 1 (YAP1) has been reported to play a key role in HCC tumorigenesis....

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.4312

    authors: Ruan T,He X,Yu J,Hang Z

    更新日期:2016-04-01 00:00:00

  • Differentially expressed miRNAs in hepatocellular carcinoma cells under hypoxic conditions are associated with transcription and phosphorylation.

    abstract::Hypoxia is a critical aspect of tumor biology and has been associated with poor prognosis and resistance to traditional therapy. In the present study, differentially expressed genes and microRNAs (miRNAs/miRs) were screened for in the hepatocellular carcinoma (HCC) cell line Huh7 under hypoxic conditions. On the basis...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.7349

    authors: Hu B,Tang WG,Fan J,Xu Y,Sun HX

    更新日期:2018-01-01 00:00:00

  • Molecular alterations in the carcinogenesis and progression of hepatocellular carcinoma: Tumor factors and background liver factors.

    abstract::Although hepatocellular carcinoma (HCC) is associated with poor prognosis worldwide, the molecular mechanisms underlying the carcinogenesis and progression of this disease remain unclear. Several tumor characteristics have previously been demonstrated to be prognostic factors of survival following hepatic resection, o...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.5141

    authors: Inokawa Y,Inaoka K,Sonohara F,Hayashi M,Kanda M,Nomoto S

    更新日期:2016-11-01 00:00:00

  • Serum IGFBP-3 is a more effective predictor than IGF-1 and IGF-2 for the development of hepatocellular carcinoma in patients with chronic HCV infection.

    abstract::Hepatocellular carcinoma (HCC) contributes to 14.8% of all cancer mortality in Egypt, which has a high prevalence of hepatitis C virus (HCV). We have previously shown alterations in the insulin-like growth factor-1 (IGF-1) receptor signalling pathway during experimental hepatocarcinogenesis. The aim of this study was ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2011.546

    authors: Aleem E,Elshayeb A,Elhabachi N,Mansour AR,Gowily A,Hela A

    更新日期:2012-03-01 00:00:00

  • The role of computed tomography and magnetic resonance imaging in diagnosing clear cell ameloblastoma: A case report.

    abstract::Ameloblastoma is the most common and clinically relevant type of odontogenic tumor. Clear cell odontogenic carcinoma is histologically characterized by solid sheets and nests of clear cells, whereas clear cell ameloblastoma (CCAM) is histologically characterized by an ameloblastomatous component intermixed with an ext...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.7116

    authors: Gamoh S,Wato M,Akiyama H,Tsuji K,Ishikawa H,Naruse K,Yoshida H,Morita S,Tanaka A,Shimizutani K

    更新日期:2017-12-01 00:00:00

  • PTPRA facilitates cancer growth and migration via the TNF-α-mediated PTPRA-NF-κB pathway in MCF-7 breast cancer cells.

    abstract::Protein tyrosine phosphatase receptor type A (PTPRA), one of the classic protein tyrosine phosphatases, is crucial for modulating tumorigenesis and metastasis in breast cancer; however, its functional mechanism has not fully elucidated. The present study assessed PTPRA expression and estimated its clinical impact on s...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2020.11992

    authors: Lin C,Xin S,Huang X,Zhang F

    更新日期:2020-11-01 00:00:00

  • Monitoring immunoglobulin heavy chain and T-cell receptor gene rearrangement in cfDNA as minimal residual disease detection for patients with acute myeloid leukemia.

    abstract::The present study aimed to examine whether monoclonal immunoglobulin heavy chain (IGH) or T-cell receptor (TCR) gene rearrangement in cell-free DNA (cfDNA) may be used for minimal residual disease (MRD) monitoring in patients with acute myeloid leukemia (AML). Monoclonal IGH and TCR rearrangement in cfDNA were monitor...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8966

    authors: Zhong L,Chen J,Huang X,Li Y,Jiang T

    更新日期:2018-08-01 00:00:00

  • Multifocal Langerhans cell histiocytosis in an adult with a pathological fracture of the mandible and spontaneous malunion: A case report.

    abstract::Langerhans cell histiocytosis (LCH) is rare in the adult population and even rarer with jaw involvement. The current study presents the case of a 39-year-old male who complained of recurrent pain, swelling of the gingiva and an occasional pus-like discharge in the right mandible for one year. The patient was previousl...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2272

    authors: Shi S,Liu Y,Fu T,Li X,Zhao S

    更新日期:2014-09-01 00:00:00

  • AKR1C1-3, notably AKR1C3, are distinct biomarkers for liver cancer diagnosis and prognosis: Database mining in malignancies.

    abstract::Aldo-keto reductases, known as AKR1C1-AKR1C4 enzymes, are pivotal to NADPH-dependent reduction, and their expression is highly associated with the progression of malignant cancers. However, the expression and distinct prognostic value of the AKR1C family members in liver cancer are not well established. In the current...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10802

    authors: Zhao SF,Wang SG,Zhao ZY,Li WL

    更新日期:2019-11-01 00:00:00

  • Role of high mobility group A1 and body mass index in the prognosis of patients with breast cancer.

    abstract::The high mobility group A1 (HMGA1) protein is associated with poor prognosis in patients with a wide range of cancers. However, the affect of HMGA1 on the risk of mortality from breast cancer (BC) has not been fully characterized. In the present retrospective multiple center study, the HMGA1 expression level was deter...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.6963

    authors: Zhang S,Lei R,Wu J,Shan J,Hu Z,Chen L,Ren X,Yao L,Wang J,Wang X

    更新日期:2017-11-01 00:00:00

  • Inhibition of tumor necrosis factor-α enhances apoptosis induced by nuclear factor-κB inhibition in leukemia cells.

    abstract::Inhibition of nuclear factor-κB (NF-κB) results in antitumor activity in leukemia cells, and may be a potential therapeutic strategy for the treatment of leukemia. However, a significant limitation of NF-κB inhibition in the treatment of leukemia is the low efficiency of this technique. NF-κB inhibitor treatment induc...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.3786

    authors: Dong QM,Ling C,Chen X,Zhao LI

    更新日期:2015-12-01 00:00:00

  • 17AAG-induced internalisation of HER2-specific Affibody molecules.

    abstract::The geldanamycin derivative 17-allylamino-17-demethoxygeldanamycin (17-AAG) is known to induce internalisation and degradation of the otherwise internalisation-resistant human epidermal growth factor receptor 2 (HER2) receptor. In the present study, 17-AAG was used to increase internalisation of the HER2-specific Affi...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.4990

    authors: Göstring L,Lindegren S,Gedda L

    更新日期:2016-10-01 00:00:00

  • Downregulation of GSK3β by miR-544a to maintain self-renewal ability of lung caner stem cells.

    abstract::In order to study the influence and mechanism of miR-544a on the self-renewal ability of lung cancer stem cells, TargetScan was used to predict the target gene of miR-544a. A luciferase reporter system and western blotting were used to validate the target genes identified by TargetScan. 95C and 95D low and high metast...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2387

    authors: Mo XM,Li HH,Liu M,Li YT

    更新日期:2014-10-01 00:00:00

  • Prognostic value of nuclear FBI-1 in patients with rectal cancer with or without preoperative radiotherapy.

    abstract::Factor that binds to the inducer of short transcripts of the human immunodeficiency virus-1 (FBI-1) represents as a crucial gene regulator in colorectal cancer; however, the correlation between FBI-1 and preoperative radiotherapy (RT) in rectal cancer (RC) has not yet been reported. The aim was to detect FBI-1 express...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10890

    authors: Wang CJ,Chao CR,Liu HM,Zhu YY,Adell G,Jarlsfelt I,Zhang H,Sun XF

    更新日期:2019-11-01 00:00:00

  • Genistein inhibits lung cancer cell stem-like characteristics by modulating MnSOD and FoxM1 expression.

    abstract::Manganese superoxide dismutase (MnSOD) promotes invasive and migratory activities by upregulating Forkhead box protein M1 (FoxM1) expression. The present study investigated whether modulation of MnSOD and FoxM1 expression was responsible for the antitumor effects of genistein on cancer stem-like cells (CSLCs) derived ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2020.11802

    authors: Fu Z,Cao X,Liu L,Cao X,Cui Y,Li X,Quan M,Ren K,Chen A,Xu C,Qiu Y,Chen X,Wang Z,Cao J

    更新日期:2020-09-01 00:00:00

  • Advanced choroidal melanoma with a desirable aesthetic outcome after enucleation: A case report.

    abstract::Choroidal melanoma is a rare ocular tumor. The present study reports the case of a 66-year-old male who presented with chronic headache and progressive visual loss. Physical eye examination and combined A- and B-mode ultrasonography detected choroidal melanoma. Due to tumor characteristics the eye was enucleated resto...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8661

    authors: Terzidou C,Trivli A,Dalianis G,Apessou D,Spandidos DA,Goulielmos GN

    更新日期:2018-07-01 00:00:00