Impact of obesity and weight loss on cardiac performance and morphology in adults.

Abstract:

:Obesity, particularly severe obesity is capable of producing hemodynamic alterations that predispose to changes in cardiac morphology and ventricular function. These include increased cardiac output, left ventricular hypertrophy and diastolic and systolic dysfunction of both ventricles. Facilitated by co-morbidities such as hypertension, the sleep apnea/obesity hypoventilation syndrome, and possibly certain neurohormonal and metabolic alterations, these abnormalities may predispose to left and right heart failure, a disorder known as obesity cardiomyopathy.

journal_name

Prog Cardiovasc Dis

authors

Alpert MA,Omran J,Mehra A,Ardhanari S

doi

10.1016/j.pcad.2013.09.003

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

391-400

issue

4

eissn

0033-0620

issn

1873-1740

pii

S0033-0620(13)00156-4

journal_volume

56

pub_type

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