Abstract：
:Valvular heart disease is a common cause of increased mean pulmonary artery pressure (PAP). Aortic stenosis and mitral regurgitation are frequently accompanied by pulmonary hypertension (PH), especially when they are severe and symptomatic. In asymptomatic patients, PH is rare, though the exact prevalence is unknown and mainly stems from the severity of the valvular heart disease and the presence of diastolic dysfunction. Exercise echocardiography has recently gained interest in depicting PH. In these asymptomatic patients, exercise PH is observed in about >40%. Either PH at rest (systolic PAP >50 mmHg) or during exercise (systolic PAP >60 mmHg) is a powerful determinant of outcome and is independently associated with reduced survival, regardless of the severity of the underlying valvular pathology.
journal_name
Prog Cardiovasc Disjournal_title
Progress in cardiovascular diseasesauthors
Martinez C,Bernard A,Dulgheru R,Incarnato P,Oury C,Lancellotti Pdoi
10.1016/j.pcad.2016.06.004subject
Has Abstractpub_date
2016-07-01 00:00:00pages
59-70issue
1eissn
0033-0620issn
1873-1740pii
S0033-0620(16)30051-2journal_volume
59pub_type
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