Abstract:
BACKGROUND:Chronic hepatitis C virus (HCV) infection is common among people who inject drugs (PWID) and is associated with morbidity and premature death. Although HCV can be cured, treatment may be inaccessible. We studied HCV testing, status and treatment among marginalized people who use drugs in Ottawa, Canada, a setting with universal insurance coverage for physician services. METHODS:We analyzed data from the Participatory Research in Ottawa: Understanding Drugs study, a cross-sectional, peer-administered survey of people who use drugs from 2012 to 2013. We linked responses to population-based health administrative databases and used multivariable Poisson regression to identify factors independently associated with self-reported HCV testing, self-reported positive HCV status, and database-determined engagement in HCV treatment. RESULTS:Among 663 participants, 562 (84.8%) reported testing for HCV and 258 (45.9%) reported HCV-positive status. In multivariable analysis, HCV-positive status was associated with female gender (RR 1.27; 95%CI 1.04 to 1.55), advancing age (RR 1.03/year; 95%CI 1.02 to 1.04), receiving disability payments (RR 1.42; 95%CI 1.06 to 1.91), injecting drugs (RR 5.11; 95%CI 2.64 to 9.91), ever injecting with a used needle (RR 1.30; 95%CI 1.12 to 1.52), and ever having taken methadone (RR 1.26; 95%CI 1.05 to 1.52). Of HCV positive participants, 196 (76%) were engaged in primary care but only 23 (8.9%) had received HCV therapy. Conclusions/Importance: Although HCV testing and positive status rates are high among PWID in our study, few have received HCV treatment. Innovative initiatives to increase access to HCV treatment for PWID are urgently needed.
journal_name
Subst Use Misusejournal_title
Substance use & misuseauthors
Boucher LM,Bayoumi AM,Mark AE,Cooper C,Martin A,Marshall Z,Boyd R,Oickle P,Diliso N,Pineau D,Renaud B,LeBlanc S,Tyndall M,Lee OM,Kendall CEdoi
10.1080/10826084.2018.1485699subject
Has Abstractpub_date
2019-01-01 00:00:00pages
18-30issue
1eissn
1082-6084issn
1532-2491journal_volume
54pub_type
杂志文章abstract::Asians have low levels of substance use compared with other groups in the United States. Given the increase in Asian population, we believe it is important to study substance use in this population. Data from the 2002-2003 National Latino and Asian American Study are examined to address two questions. First, which Asi...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2011.605415
更新日期:2011-01-01 00:00:00
abstract::Although the prevention of intimate partner violence is a major public health priority for the United States, little is known about how to prevent this form of violence. The strong cross-sectional and longitudinal association between substance misuse and partner violence suggests that substance-misusing populations ma...
journal_title:Substance use & misuse
pub_type: 杂志文章,评审
doi:10.1080/10826080902961377
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:People living with HIV/AIDS (PLWHA) who smoke cigarettes are vulnerable to greater pain and aberrant use of prescription pain medications. Prescription opioid misuse is highly prevalent among PLWHA and can lead to a variety of adverse outcomes. Pain-related anxiety, which has been implicated in the maintenan...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2018.1464028
更新日期:2018-11-10 00:00:00
abstract::This study explores the environmental, clinical, and personality factors that are associated with increased chronic psychotropic drug consumption in elderly patients. We collected data from 88 elderly individuals living in nursing homes, home-dwellings, and residential homes between December 2003 and June 2004. We ass...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826080903550521
更新日期:2010-06-01 00:00:00
abstract::Using data collected from a 1999 nationwide survey of 700 incarcerated drug users in Taiwan, this article compares gender differences with respect to childhood experiences, family characteristics, drug use patterns, and criminal histories. The results from both bivariate and logistic regression analyses document some ...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1081/ja-120017618
更新日期:2003-06-01 00:00:00
abstract::We examined relationships among perceived alcohol availability, drinking location, alcohol consumption, and drinking problems. Subjects were 3,372 adolescent drinkers, ages 16-18, who participated in the Communities Mobilizing for Change on Alcohol Project baseline survey. Mixed-model regression was employed to identi...
journal_title:Substance use & misuse
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/10826089709039378
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:The population of adults accessing opioid treatment is growing older, but exact estimates vary widely, and little is known about the characteristics of the aging treatment population. Further, there has been little research regarding the epidemiology, healt h status, and functional impairments in this popula...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2015.1027929
更新日期:2015-01-01 00:00:00
abstract::The upsurge of consumption of party drugs among adolescents in recent years in Hong Kong has been part of the global trend of adolescent recreational use of drugs at rave parties, discos and similar party settings. Scholars in Western societies have recently proposed the thesis of "normalization of adolescent drug use...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826080601026019
更新日期:2006-01-01 00:00:00
abstract::Volatile substance misuse (VSM) is prevalent in the United States and associated with manifold deleterious outcomes. This review summarizes research on: (1) the prevalence of VSM in the United States and its trends since 1975, (2) population subgroups at an elevated risk for VSM, (3) key correlates of VSM, (4) psychos...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2011.580172
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION AND AIM:Substance abuse exacts considerable social and health care burdens throughout the world. The aim of this study was to create a prediction model to better identify risk factors for drug use. DESIGN AND METHODS:A prospective cross-sectional study was conducted in South Khorasan Province, Iran. Of th...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2017.1392981
更新日期:2018-05-12 00:00:00
abstract::Background: Alcohol harm is a major contributor to the burden of disease in South Africa. This study aimed to identify the extent of heavy drinking and symptoms of alcohol problems among adult drinkers and associated demographic and other risk factors in the Tshwane Metropole of South Africa. Methods: A household surv...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2019.1609987
更新日期:2019-01-01 00:00:00
abstract::Patterns of risk in injecting drug user (IDU) networks have been a key focus of network approaches to HIV transmission histories. New network modeling techniques allow for a reexamination of these patterns with greater statistical accuracy and the comparative weighting of model elements. This paper describes the resul...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2013.796987
更新日期:2013-12-01 00:00:00
abstract::Implementation of Temporary Assistance for Needy Families (TANF) presents welfare recipients with time-limited benefits and work requirements. However, it is estimated that over 140,000 welfare recipients meet the DSM-IV criteria for "drug dependence". In this study, samples of chronic drug using and non-drug using fe...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1081/ja-100104090
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Little research has focused specifically on alcohol, tobacco, and other drug (ATOD) use of lesbian and bisexual women in general or the college subgroup specifically. Previous research shows sexual minority women at increased risk when compared to their heterosexual counterparts. OBJECTIVES:The purpose of t...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2014.980954
更新日期:2015-02-01 00:00:00
abstract::This article discusses the conceptual, ethical, and policy issues raised by the legal classification of drug addiction as an impairment, and of some nonusing drug addicts as people with disabilities. It focuses on the questions of (1) what moral judgments, if any, underlie the classification of addiction as an impairm...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1081/ja-120029986
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Drug use is associated with intimate partner violence (IPV) perpetration among men, but few studies have examined the relation between prescription opioid misuse and IPV perpetration. Objectives: The purpose of this study is to examine the relation between prescription opioid misuse and IPV perpetration whil...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2020.1784945
更新日期:2020-01-01 00:00:00
abstract::Parental substance misuse has often been cited as a cause of children being referred for investigation of child abuse and neglect. Research on how the substance use environment might affect this relationship is still in its infancy with primarily only cross-sectional studies finding a positive relationship of alcohol ...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826080701690649
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:This report documents the prevalence of hepatitis C virus (HCV) infection among self-reported noninjecting drug users recruited from two New York City neighborhoods. METHODS:Participants were recruited in separate studies from East Harlem and the Lower East Side of Manhattan and were administered structured...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1081/ja-100102640
更新日期:2001-03-01 00:00:00
abstract::We used an ecological paradigm and multilevel analytic techniques to analyze gender-specific relationships of cohabitation (versus marriage) to drinking in 19 countries (n = 32,922) and to "heavy episodic drinking" (HED) in 17 countries (n = 24,525) in surveys (1996-2004) from Gender, Alcohol, and Culture: An Internat...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826081003692106
更新日期:2010-12-01 00:00:00
abstract::The stress-negative affect model for alcohol use was examined. The mediating roles of different components of negative affect were tested in the context of coping style. Data from 1,057 drinking adults (Mage = 44.45) and 352 drinking college students (Mage = 19.07) collected during 2001-2005 and in 2010, respectively,...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2012.761713
更新日期:2013-03-01 00:00:00
abstract::This investigation evaluated the effect of expressive writing on weight gain in young adults being treated for smoking cessation. This study was conducted between July 2001 and June 2005. Participants (N = 196) ages 18-24 years (M = 20.8, SD = 2.0 years), who were recruited from a large city in the southeastern United...
journal_title:Substance use & misuse
pub_type: 杂志文章,随机对照试验
doi:10.1080/10826080801922082
更新日期:2008-01-01 00:00:00
abstract::Few studies examine whether early sexual experience is associated with subsequent illegal drug use among adolescents. A sample of 7,372 African American students who had not used illegal drugs before the age of 14 were identified in the dataset of the 2001 Historically Black Colleges and Universities (HBCU) Substance ...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2010.509853
更新日期:2011-01-01 00:00:00
abstract::Therapeutic interventions to treat alcoholism have increased in number, including several pharmacotherapies. Aspects of epidemiology, gender, and psychiatric comorbidity as well as a brief overview of neurobiology are presented as an introduction. The medications used clinically for the treatment of alcoholism, disulf...
journal_title:Substance use & misuse
pub_type: 杂志文章,评审
doi:10.1080/10826080500294890
更新日期:2005-01-01 00:00:00
abstract::The aim of the present study was to examine the effect of the unique characteristics of residing in security and political conflict zones on the willingness to use and on the actual abuse of psychoactive substances. The study focuses on the differences between youths residing in and outside conflict zones in Israel. T...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2016.1245344
更新日期:2017-08-24 00:00:00
abstract::The article presents practical and methodological strategies in the tracking and retention of a longitudinal community-based sample of 300 Mexican American noninjecting users of heroin. Presented are the ethnographic strategies the research team utilized to maintain high retention rates among this highly marginalized ...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826081003591282
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Extended-release naltrexone (XRNT) was developed to overcome poor treatment compliance with oral naltrexone in alcohol and opioid-dependent patients. XRNT injections are registered in the United States and Russia, but not in The Netherlands. However, XRNT can be obtained for individual patients, but it is ex...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2016.1201117
更新日期:2016-12-05 00:00:00
abstract::The purpose of this study is to compare rural and urban substance abuse counselors' perceptions of barriers to providing effective treatment services. Data were collected from 28 substance abuse counselors in Kentucky during four focus group sessions in 2008. Line-by-line coding and memoing were used by two raters on ...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2014.891615
更新日期:2014-06-01 00:00:00
abstract::Background: Several records of high prevalence of HBV have been made in northern Brazil. Among risk groups for viral infection, people who use illicit drugs (PWUDs) stand out, especially if they inject drugs and engage in risky sexual behavior. Objectives: In this study, the prevalence, genotype distribution and facto...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2020.1756334
更新日期:2020-01-01 00:00:00
abstract::There is a large literature on substance misuse and interpersonal aggression, including aggression perpetrated by women in treatment for substance misuse. There is also a growing body of literature on mindfulness and substance use, as well as mindfulness and aggression. However, to date, there has been little research...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.3109/10826084.2015.1050112
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Alcohol use/misuse is a prevalent health issue among youth and may lead to adverse consequences. Religiosity has been identified as a protective factor against alcohol use/misuse among youth. Identifying moderators in the religiosity-alcohol relationship has important implications for intervention developmen...
journal_title:Substance use & misuse
pub_type: 杂志文章
doi:10.1080/10826084.2018.1555598
更新日期:2019-01-01 00:00:00