Abstract:
:Screening for HIV infection has improved since the first immunoassays. Today, diagnosis of HIV infection can be performed with fourth-generation tests that track both the patient's antibodies and HIV antigen. The objective of this study was to evaluate the clinical sensitivity and specificity of the new DiaSorin Liaison XL Murex HIV Ab/Ag assay compared to another fourth-generation assay, the Abbott Architect HIV Ag/Ab Combo kit. This work was performed on a large panel of 900 samples, including negative samples (n = 493) and HIV-positive (n = 407) representatives of HIV-1 group M subtypes and circulating recombinant forms (CRFs), HIV-1 group O, and HIV-2 variants. The results highlight the high specificity (98.9%) and sensitivity (100%) of this new fourth-generation assay, which are consistent with its use for the screening and diagnosis of HIV infections with the current circulating strains.
journal_name
J Clin Microbioljournal_title
Journal of clinical microbiologyauthors
Lemee V,Leoz M,Etienne M,De Oliveira F,Plantier JCdoi
10.1128/JCM.01089-14subject
Has Abstractpub_date
2014-09-01 00:00:00pages
3277-9issue
9eissn
0095-1137issn
1098-660Xpii
JCM.01089-14journal_volume
52pub_type
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:10.1128/JCM.10.1.32-36.1979
更新日期:1979-07-01 00:00:00
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journal_title:Journal of clinical microbiology
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journal_title:Journal of clinical microbiology
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更新日期:1984-05-01 00:00:00
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
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journal_title:Journal of clinical microbiology
pub_type: 杂志文章
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更新日期:1988-02-01 00:00:00
abstract::The supposedly first outbreak of hepatitis D virus (HDV) infection in Sweden occurred among intravenous drug addicts in the Malmö area in the mid-1970s. Stored sera from this outbreak were used for viral RNA extraction and analysis. By sequence comparisons, the HDV genomes from those Swedish patients fell into two sep...
journal_title:Journal of clinical microbiology
pub_type: 杂志文章
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