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Efficacy of early passive tilting in minimizing ICU-acquired weakness: A randomized controlled trial.

Abstract：

Purpose:To investigate whether passive tilting added to a standardized rehabilitation therapy improved strength at Intensive Care Unit (ICU) discharge. Material and methods:This single-center trial included patients admitted to an adult surgical ICU and ventilated for at least 3 days. Patients were randomized to daily standardized rehabilitation therapy alone or with tilting on a table for at least 1 h. The primary outcome was the Medical Research Council (MRC) sum score at ICU discharge. Muscular recovery was a secondary outcome. Results:Of 145 included patients, 125 received mobilization, 65 in the Tilt group and 60 in the Control group. Total mobilization duration (median [25th–75th percentiles]) in the Tilt group was 1020 [580–1695] versus 1340 [536–2775] minutes in the Control group (p = 0.313). MRC sum scores at ICU discharge were not significantly different between groups (Tilt, 50 [45–56] versus 48 [45–54]; p = 0.555). However, the number of patients with weakness was higher in the Tilt group at baseline (Tilt: 60/65 versus 48/60, p = 0.045) and muscular recovery was better in the Tilt group (p = 0.004). Conclusions:Passive tilting added to a standardized rehabilitation therapy did not improve muscle strength at ICU discharge in surgical patients even if a faster recovery with tilting is suggested.

journal_name

J Crit Care

journal_title

Journal of critical care

authors

Sarfati C,Moore A,Pilorge C,Amaru P,Mendialdua P,Rodet E,Stéphan F,Rezaiguia-Delclaux S

doi

10.1016/j.jcrc.2018.03.031

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

37-43

eissn

0883-9441

issn

1557-8615

pii

S0883-9441(18)30108-4

journal_volume

46

pub_type

杂志文章,随机对照试验

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