Abstract：
:Apelin is an endogenous inotrope that decreased in heart failure (HF). We aimed to evaluate the prognostic value of its level in children with HF due to congenital heart disease (CHD). Sixty children with HF due to CHD were included as a patient group. Sixty healthy children matched for age, sex, and weight served as a control group. Chest X-ray, electrocardiogram (ECG), echocardiography, and laboratory investigations such as complete blood count, c-reactive protein, and serum apelin levels were performed for all included children at admission. All children were followed up for 3 months. Serum apelin level was significantly decreased in patients with HF at admission than healthy control group and this decrease went with advanced stage of HF. Serum apelin levels were significantly decreased in patients with unfavorable prognosis than those with favorable prognosis. At a cutoff lower than 126 ng/l, the sensitivity of serum apelin to predict unfavorable prognosis in children with HF was 96% with a specificity of 82%. Serum apelin level had a significant positive correlation with left ventricular systolic function (P < 0.05). Moreover, it had a significant negative correlation with heart rate, respiratory rate, Ross classification, c-reactive protein, cardiothoracic ratio, and both left and right ventricular dimensions (P < 0.05). Serum apelin level has a good predictive value for adverse outcome in children with HF due to CHD.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
El Amrousy D,El-Mahdy Hdoi
10.1007/s00246-018-1879-7subject
Has Abstractpub_date
2018-08-01 00:00:00pages
1188-1193issue
6eissn
0172-0643issn
1432-1971pii
10.1007/s00246-018-1879-7journal_volume
39pub_type
杂志文章abstract：:We sought to describe the use and outcomes of small, medium and large premounted stents in patients with congenital heart disease, including incidence of and risk factors for re-intervention and development of in-stent stenosis. Premounted stents offer several advantages over traditional manually crimped bare-metal st...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1466-8
更新日期：2016-12-01 00:00:00
abstract：:Congenital heart disease (CHD) is the most common congenital anomaly, affecting 1 % of live births. The field of pediatric cardiology has witnessed major advances over the past 25 years triggered by research initiatives focusing on CHD. However, large disparities exist in research capabilities between Arab developing ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-012-0466-6
更新日期：2013-02-01 00:00:00
abstract：:Increased risk of perioperative hemorrhage has been described in patients with Turner syndrome and coarctation of the aorta. We have operated on 11 patients with Turner syndrome and coarctation of the aorta, two of whom developed bleeding. One patient died. End-to-end anastomosis was performed in all patients. Histolo...
journal_title：Pediatric cardiology
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doi：10.1007/BF02427041
更新日期：1984-07-01 00:00:00
abstract：:This study is presented to identify and characterize the spectrum of the cardiovascular anomalies in children presenting with Williams-Beuren syndrome and cardiovascular anomalies at The Hospital for Sick Children, Toronto from 1966 to 1988. Forty-nine children were diagnosed and followed. The female to male ratio was...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02310569
更新日期：1991-10-01 00:00:00
abstract：:This study examined the age-related criteria of signal-averaged electrocardiographic (SA-ECG) parameters in children. SA-ECGs were obtained in 82 healthy volunteers in six groups depending on age (group 1: 1 day to < 1 month; group 2: 1 month to < 1 year; group 3: 1 to < 6 years; group 4: 6 to < 12 years; group 5: 12 ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796320
更新日期：1994-05-01 00:00:00
abstract：:We report a rare case of tetralogy of Fallot with total anomalous pulmonary venous return, left heart hypoplasia, right lung hypoplasia, and left ocular-mandibular synchinesia (Marcus-Gunn phenomenon), correctly diagnosed by cardiovascular magnetic resonance imaging and successfully operated by modified Glenn anastomo...
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doi：10.1007/s00246-004-0769-3
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abstract：:Plastic bronchitis is a rare, potentially life-threatening condition in which protein casts form within and occlude the bronchus, resulting in pulmonary failure, and has been identified as a complication after the Fontan procedure. We present a case of a 5-year-old girl who had undergone an extracardiac fenestrated Fo...
journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：2005-09-01 00:00:00
abstract：:Right ventricular (RV) pacing can be associated with impairment of left ventricular (LV) function due to electrical dyssynchrony and myocardial remodeling (Janousek et al. in J Cardiovasc Electrophysiol 15:470-474, 2004). RV-pacing induced ventricular dysfunction is reversible by techniques such as biventricular pacin...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1629-2
更新日期：2017-08-01 00:00:00
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更新日期：2012-01-01 00:00:00
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更新日期：2015-12-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：2004-03-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02238530
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journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章,多中心研究
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更新日期：2017-04-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9025-y
更新日期：2008-03-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900341
更新日期：1998-09-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0880-z
更新日期：2014-08-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02336549
更新日期：1985-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：1995-09-01 00:00:00
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journal_title：Pediatric cardiology
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更新日期：2001-11-01 00:00:00
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：2000-09-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02315475
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：2013-04-01 00:00:00
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journal_title：Pediatric cardiology
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更新日期：2019-03-01 00:00:00
