Abstract:
:This study identified tracheobronchial cartilage calcification in children with congenital heart disease. Calcification of the tracheobronchial airways has been found previously in adults receiving warfarin and in children receiving warfarin after mitral valve replacement. A 9-year-old girl who had received a Fontan repair 6 years previously underwent a cardiac computed tomography (CT) scan to evaluate pulmonary artery size. The result was an incidental finding of extensive tracheobronchial cartilage calcification. A retrospective review of all pediatric Fontan patients who had undergone cardiac CT was conducted to search for calcification of the tracheobronchial cartilage. The study investigated ten pediatric Fontan patients who had undergone cardiac CT scanning. Two patients with extensive calcification of the tracheobronchial airways were identified. The index case had hypoplastic left heart syndrome, and the patient had undergone a staged repair with the Fontan at the age of 3 years. A 16-year-old boy with tricuspid atresia had undergone staged repair and Fontan at the age of 3.5 years. These two patients had received continuous warfarin therapy for 6 and 13 years, respectively. Other common causes of airway calcification were excluded from the study. This report describes warfarin-induced tracheobronchial calcification in patients after the Fontan procedure. This finding has possible implications for airway growth and vascular calcification.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Eckersley L,Stirling J,Occleshaw C,Wilson Ndoi
10.1007/s00246-014-0880-zsubject
Has Abstractpub_date
2014-08-01 00:00:00pages
954-8issue
6eissn
0172-0643issn
1432-1971journal_volume
35pub_type
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journal_title:Pediatric cardiology
pub_type: 杂志文章
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
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journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:1995-07-01 00:00:00
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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更新日期:2013-03-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9595-y
更新日期:2010-02-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0430-5
更新日期:2013-02-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02306750
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the associations between clinical factors and cardiac function as measured by pressure-volume loops (PVLs) in a pediatric heart transplant cohort. METHODS:Patients (age < 20 years) who underwent heart transplantation presenting for a clinically indicated catheter...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-017-1758-7
更新日期:2018-02-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00798120
更新日期:1994-11-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02376-1
更新日期:2020-08-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900470
更新日期:1999-07-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-002-0131-6
更新日期:2003-09-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9735-4
更新日期:2010-08-01 00:00:00
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journal_title:Pediatric cardiology
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doi:10.1007/s00246-005-0913-8
更新日期:2005-09-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02317-y
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-004-0886-z
更新日期:2005-09-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
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更新日期:2004-01-01 00:00:00
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更新日期:2020-10-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02310996
更新日期:1986-01-01 00:00:00
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更新日期:2015-02-01 00:00:00
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journal_title:Pediatric cardiology
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更新日期:2016-12-01 00:00:00
abstract::The neonatal Marfan syndrome is an autosomal dominantly inherited disease with an extremely poor prognosis. This report gives a clinical and echocardiographic description of an infant with a mutation in exon 29 of the fibrillin-1 gene (FBN1), a region in which this severe form of Marfan syndrome seems to cluster. The ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:1999-09-01 00:00:00