An actinomycete isolate from solitary wasp mud nest having strong antibacterial activity and kills the Candida cells due to the shrinkage and the cytosolic loss.

Abstract:

:An actinomycetes strain designated as MN 2(6) was isolated from the solitary wasp mud nest. The isolate was identified using polyphasic taxonomy. It produced the extensive branched brown substrate and white aerial hyphae that changed into grayish black. The aerial mycelia produced the spiral spore chains with rugose spore surface. The growth was observed between temperature range of 27-37°C, pH 8-10 and below salt concentration of 6% (w/v). The comparative analysis of 16S rRNA gene sequence and phylogenetic relationship showed that strain MN 2(6) lies in clade with Streptomyces hygroscopicus subsp. hygroscopicus NRRL 2387(T), Streptomyces sporocinereus NBRC 100766(T) and Streptomyces demainii NRRL B-1478(T) with which it shares a 16S rRNA gene sequence similarity of 99.3%. The strain MN 2(6) can be differentiated from type strains based on phenotypic characteristics. The strain MN 2(6) showed most promising activity against Gram-positive, Gram-negative bacteria, acid-fast bacilli and Candida species suggesting broad-spectrum characteristics of the active metabolite. Evaluation of anti-candidal activity of the metabolite of strain MN 2(6) by scanning electron microscopy (SEM) revealed changed external morphology of yeast. It kills the Candida cells due to the shrinkage and the cytosolic loss. However, further studies are required to elucidate the structure of the active metabolite produced by the isolate MN 2(6).

journal_name

Front Microbiol

authors

Kumar V,Naik B,Gusain O,Bisht GS

doi

10.3389/fmicb.2014.00446

subject

Has Abstract

pub_date

2014-08-21 00:00:00

pages

446

issn

1664-302X

journal_volume

5

pub_type

杂志文章
  • Framework for Quantification of the Dynamics of Root Colonization by Pseudomonas fluorescens Isolate SBW25.

    abstract::Colonization of the root surface, or rhizoplane, is one of the first steps for soil-borne bacteria to become established in the plant microbiome. However, the relative contributions of processes, such as bacterial attachment and proliferation is not well characterized, and this limits our ability to comprehend the com...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.585443

    authors: Carroll D,Holden N,Gifford ML,Dupuy LX

    更新日期:2020-09-25 00:00:00

  • Porcine Circovirus-Like Virus P1 Inhibits Wnt Signaling Pathway in Vivo and in Vitro.

    abstract::Porcine circovirus-like virus P1 is an important pathogen of the current pig industry, the infection mechanism is not entirely clear. Wnt signaling pathway plays an important role in the growth of young animals and infection of some viruses. This study was designed to demonstrate the effects of P1 infection on the Wnt...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00390

    authors: Zhu X,Wen L,Sheng S,Wang W,Xiao Q,Qu M,Hu Y,Liu C,He K

    更新日期:2018-03-12 00:00:00

  • Aspergillus niger Secretes Citrate to Increase Iron Bioavailability.

    abstract::Aspergillus niger has an innate ability to secrete various organic acids, including citrate. The conditions required for A. niger citrate overproduction are well described, but the physiological reasons underlying extracellular citrate accumulation are not yet fully understood. One of the less understood culture condi...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01424

    authors: Odoni DI,van Gaal MP,Schonewille T,Tamayo-Ramos JA,Martins Dos Santos VAP,Suarez-Diez M,Schaap PJ

    更新日期:2017-08-02 00:00:00

  • PNA Length Restriction of Antibacterial Activity of Peptide-PNA Conjugates in Escherichia coli Through Effects of the Inner Membrane.

    abstract::Peptide Nucleic Acid (PNA)-peptide conjugates targeting essential bacterial genes are showing promise as antisense antimicrobials in drug discovery. Optimization has focused on selection of target genes and exact localization around the ribosome binding site, but surprisingly a length optimum around 10-12 nucleobases ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01032

    authors: Goltermann L,Yavari N,Zhang M,Ghosal A,Nielsen PE

    更新日期:2019-05-24 00:00:00

  • Antimicrobial active herbal compounds against Acinetobacter baumannii and other pathogens.

    abstract::Bacterial pathogens cause a number of lethal diseases. Opportunistic bacterial pathogens grouped into ESKAPE pathogens that are linked to the high degree of morbidity, mortality and increased costs as described by Infectious Disease Society of America. Acinetobacter baumannii is one of the ESKAPE pathogens which cause...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2015.00618

    authors: Tiwari V,Roy R,Tiwari M

    更新日期:2015-06-18 00:00:00

  • Intestinal Microbiome-Metabolome Responses to Essential Oils in Piglets.

    abstract::This study investigated the effects of dietary essential oils (EOs) on intestinal microbial composition and metabolic profiles in weaned piglets. The piglets were fed the same basal diet supplemented with EOs (EO) or without EOs (Con) in the current study. The results showed that the body weight gain was significantly...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.01988

    authors: Li Y,Fu X,Ma X,Geng S,Jiang X,Huang Q,Hu C,Han X

    更新日期:2018-08-28 00:00:00

  • Oral Treatments With Probiotics and Live Salmonella Vaccine Induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens.

    abstract::Cross-talk between the gut microbiota and neurochemicals affects health and well-being of animals. However, little is known about this interaction in chickens despite their importance in food production. Probiotics and live Salmonella vaccines are microbial products commonly given orally to layer pullets to improve he...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.03064

    authors: Redweik GAJ,Daniels K,Severin AJ,Lyte M,Mellata M

    更新日期:2020-01-15 00:00:00

  • Detection and Genetic Characterization of Atypical Porcine Pestivirus in Piglets With Congenital Tremors in Southern China.

    abstract::Atypical porcine pestivirus (APPV) is an RNA virus newly discovered from swine in Asia, Europe, and the Americas. This novel virus has been confirmed as the cause of congenital tremor (CT) in piglets, which causes extensive economic losses to the swine industry. To investigate the genetic diversity and evolutionary re...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01406

    authors: Xie Y,Wang X,Su D,Feng J,Wei L,Cai W,Li J,Lin S,Yan H,He D

    更新日期:2019-06-20 00:00:00

  • Prevalence, Virulence Characterization, AMR Pattern and Genetic Relatedness of Vibrio parahaemolyticus Isolates From Retail Seafood of Kerala, India.

    abstract::Vibrio parahaemolyticus, a halophilic bacterium often found in the marine or estuarine environment is a well-known enteropathogen responsible for foodborne outbreaks associated with seafood. The pathogenic strains of V. parahaemolyticus are marked by the presence of thermostable direct hemoylsin (tdh) and/or TDH relat...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00592

    authors: Narayanan SV,Joseph TC,Peeralil S,Mothadaka MP,Lalitha KV

    更新日期:2020-04-07 00:00:00

  • Soil microbial responses to nitrogen addition in arid ecosystems.

    abstract::The N cycle of arid ecosystems is influenced by low soil organic matter, high soil pH, and extremes in water potential and temperature that lead to open canopies and development of biological soil crusts (biocrusts). We investigated the effects of N amendment on soil microbial dynamics in a Larrea tridentata-Ambrosia ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.00819

    authors: Sinsabaugh RL,Belnap J,Rudgers J,Kuske CR,Martinez N,Sandquist D

    更新日期:2015-08-14 00:00:00

  • Role of Bacteriophages in the Implementation of a Sustainable Dairy Chain.

    abstract::The growing human population is currently facing an unprecedented challenge regarding global food sustainability. Thus, it is of paramount to maintain food production and quality while avoiding a negative impact on climate change and the environment at large. Along the food chain, several practices could compromise fu...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2019.00012

    authors: Gutiérrez D,Fernández L,Rodríguez A,García P

    更新日期:2019-01-22 00:00:00

  • Ff-nano, short functionalized nanorods derived from Ff (f1, fd, or M13) filamentous bacteriophage.

    abstract::F-specific filamentous phage of Escherichia coli (Ff: f1, M13, or fd) are long thin filaments (860 nm × 6 nm). They have been a major workhorse in display technologies and bionanotechnology; however, some applications are limited by the high length-to-diameter ratio of Ff. Furthermore, use of functionalized Ff outside...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.00316

    authors: Sattar S,Bennett NJ,Wen WX,Guthrie JM,Blackwell LF,Conway JF,Rakonjac J

    更新日期:2015-04-20 00:00:00

  • Role of Ezrin Phosphorylation in HIV-1 Replication.

    abstract::Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release. We analyzed the effects of ezrin mutations involving substitutio...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.01912

    authors: Kamiyama H,Izumida M,Umemura Y,Hayashi H,Matsuyama T,Kubo Y

    更新日期:2018-08-27 00:00:00

  • Antibiotic Resistance: Moving From Individual Health Norms to Social Norms in One Health and Global Health.

    abstract::Antibiotic resistance is a problem for human health, and consequently, its study had been traditionally focused toward its impact for the success of treating human infections in individual patients (individual health). Nevertheless, antibiotic-resistant bacteria and antibiotic resistance genes are not confined only to...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2020.01914

    authors: Hernando-Amado S,Coque TM,Baquero F,Martínez JL

    更新日期:2020-08-28 00:00:00

  • Mechanism and In Vivo Evaluation: Photodynamic Antibacterial Chemotherapy of Lysine-Porphyrin Conjugate.

    abstract::Lysine-porphyrin conjugate 4i has potent photosensitive antibacterial effect on clinical isolated bacterial strains such as Methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, and Pseudomonas aeruginosa. The mechanism of photodynamic antibacterial chemotherapy of 4i (4i-PACT) in vitro and the treatme...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.00242

    authors: Xu Z,Gao Y,Meng S,Yang B,Pang L,Wang C,Liu T

    更新日期:2016-03-02 00:00:00

  • Burn Injury Leads to Increase in Relative Abundance of Opportunistic Pathogens in the Rat Gastrointestinal Microbiome.

    abstract::The gastrointestinal microbiome is crucial in human health. With greater than 10 times the cell count of an individual, the gastrointestinal microbiome provides many benefits to the host. It plays an important role in chronic illnesses and immune diseases and also following burns and trauma. This study aimed to determ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01237

    authors: Huang G,Sun K,Yin S,Jiang B,Chen Y,Gong Y,Chen Y,Yang Z,Chen J,Yuan Z,Peng Y

    更新日期:2017-07-06 00:00:00

  • An Essential Factor for High Mg2+ Tolerance of Staphylococcus aureus.

    abstract::Internal bacterial concentration of Mg2+, the most abundant divalent cation in living cells, is estimated to be in the single millimolar range. However, many bacteria will thrive in media with only micromolars of Mg2+, by using a range of intensely studied and highly efficient import mechanisms, as well as in media wi...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.01888

    authors: Armitano J,Redder P,Guimarães VA,Linder P

    更新日期:2016-11-25 00:00:00

  • Evaluation of Recombinant Multi-Epitope Outer Membrane Protein-Based Klebsiella pneumoniae Subunit Vaccine in Mouse Model.

    abstract::Safety and protective efficacy of recombinant multi-epitope subunit vaccine (r-AK36) was evaluated in a mouse model. Recombinant AK36 protein comprised of immunodominant antigens from outer membrane proteins (Omp's) of Klebsiella pneumoniae namely OmpA and OmpK36. r-AK36 was highly immunogenic and the hyperimmune sera...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01805

    authors: Babu L,Uppalapati SR,Sripathy MH,Reddy PN

    更新日期:2017-09-20 00:00:00

  • Meta-Analysis of Vaginal Microbiome Data Provides New Insights Into Preterm Birth.

    abstract::Preterm birth (PTB) is defined as the birth of an infant before 37 weeks of gestational age. It is the leading cause of perinatal morbidity and mortality worldwide. In this study, we present a comprehensive meta-analysis of vaginal microbiome in PTB. We integrated raw longitudinal 16S rRNA vaginal microbiome data from...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00476

    authors: Kosti I,Lyalina S,Pollard KS,Butte AJ,Sirota M

    更新日期:2020-04-08 00:00:00

  • The Microbiome of Prostate Fluid Is Associated With Prostate Cancer.

    abstract:Objectives:To explore the microbiome of the prostatic fluid in high prostate-specific antigen (PSA) patients. Patients and Methods:The microbiome profiles of prostatic fluid samples from 32 prostate cancer (PCa) patients and 27 non-PCa people were assessed. Microbiome analysis was assessed by massive 16S ribosomal RNA...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01664

    authors: Ma X,Chi C,Fan L,Dong B,Shao X,Xie S,Li M,Xue W

    更新日期:2019-07-19 00:00:00

  • Aeolian Prokaryotic Communities of the Global Dust Belt Over the Red Sea.

    abstract::Aeolian prokaryotic communities (APC) are important components of bioaerosols that are transported freely or attached to dust particles suspended in the atmosphere. Terrestrial and marine ecosystems are known to release and receive significant prokaryote loads into and from the surrounded atmospheric air. However, com...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.538476

    authors: Aalismail NA,Díaz-Rúa R,Ngugi DK,Cusack M,Duarte CM

    更新日期:2020-11-12 00:00:00

  • Metagenomic analysis reveals that modern microbialites and polar microbial mats have similar taxonomic and functional potential.

    abstract::Within the subarctic climate of Clinton Creek, Yukon, Canada, lies an abandoned and flooded open-pit asbestos mine that harbors rapidly growing microbialites. To understand their formation we completed a metagenomic community profile of the microbialites and their surrounding sediments. Assembled metagenomic data reve...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.00966

    authors: White RA 3rd,Power IM,Dipple GM,Southam G,Suttle CA

    更新日期:2015-09-23 00:00:00

  • Abnormal fermentations in table-olive processing: microbial origin and sensory evaluation.

    abstract::The process of transformation of table olives from tree to table is the result of complex biochemical reactions that are determined by the interactions between the indigenous microflora of the olives, together with a variety of contaminating microrganisms from different sources [fiber-glass fermenters, polyvinyl chlor...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2013.00091

    authors: Lanza B

    更新日期:2013-05-10 00:00:00

  • First Report of CD4 Lymphopenia and Defective Neutrophil Functions in a Patient with Amebiasis Associated with CMV Reactivation and Severe Bacterial and Fungal Infections.

    abstract::We report the case of a patient with acute necrotizing colitis due to invasive amebiasis associated with CD4 lymphopenia and impaired neutrophil responses. The course of the disease was characterized by CMV reactivation and severe and recurrent bacterial and fungal infections, which might be related to the decreased C...

    journal_title:Frontiers in microbiology

    pub_type:

    doi:10.3389/fmicb.2017.00203

    authors: Ghrenassia E,Guihot A,Dong Y,Robinet P,Fontaine T,Lacombe K,Lescot T,Meyohas MC,Elbim C

    更新日期:2017-02-13 00:00:00

  • Abundance of Colistin-Resistant, OXA-23- and ArmA-Producing Acinetobacter baumannii Belonging to International Clone 2 in Greece.

    abstract::Carbapenem resistant Acinetobacter baumannii (CRAB) represents one of the most challenging pathogens in clinical settings. Colistin is routinely used for treatment of infections by this pathogen, but increasing colistin resistance has been reported. We obtained 122 CRAB isolates from nine Greek hospitals between 2015 ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00668

    authors: Palmieri M,D'Andrea MM,Pelegrin AC,Perrot N,Mirande C,Blanc B,Legakis N,Goossens H,Rossolini GM,van Belkum A

    更新日期:2020-04-15 00:00:00

  • Emerging Trends in Biological Treatment of Wastewater From Unconventional Oil and Gas Extraction.

    abstract::Unconventional oil and gas exploration generates an enormous quantity of wastewater, commonly referred to as flowback and produced water (FPW). Limited freshwater resources and stringent disposal regulations have provided impetus for FPW reuse. Organic and inorganic compounds released from the shale/brine formation, m...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2020.569019

    authors: Acharya SM,Chakraborty R,Tringe SG

    更新日期:2020-09-09 00:00:00

  • Corrigendum: Evaluation of Human Milk Microbiota by 16S rRNA Gene Next-Generation Sequencing (NGS) and Cultivation/MALDI-TOF Mass Spectrometry Identification.

    abstract::[This corrects the article DOI: 10.3389/fmicb.2019.02612.]. ...

    journal_title:Frontiers in microbiology

    pub_type: 已发布勘误

    doi:10.3389/fmicb.2020.00031

    authors: Treven P,Mahnič A,Rupnik M,Golob M,Pirš T,Matijašić BB,Lorbeg PM

    更新日期:2020-01-29 00:00:00

  • Extracellular DNA metabolism in Haloferax volcanii.

    abstract::Extracellular DNA is found in all environments and is a dynamic component of the microbial ecosystem. Microbial cells produce and interact with extracellular DNA through many endogenous mechanisms. Extracellular DNA is processed and internalized for use as genetic information and as a major source of macronutrients, a...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2014.00057

    authors: Chimileski S,Dolas K,Naor A,Gophna U,Papke RT

    更新日期:2014-02-20 00:00:00

  • The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells.

    abstract::Kaposi sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi sarcoma (KS) and certain rare B cell lymphoproliferative disorders. KSHV infection of endothelial cells (EC) in vitro increases expression of the inducible host-encoded enzyme heme oxygenase-1 (HO-1), which is also strongly expressed in KS tumors. HO-1...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.00568

    authors: Botto S,Gustin JK,Moses AV

    更新日期:2017-04-03 00:00:00

  • Genetic Transformation of the Filamentous Fungus Pseudogymnoascus verrucosus of Antarctic Origin.

    abstract::Cold-adapted fungi isolated from Antarctica, in particular those belonging to the genus Pseudogymnoascus, are producers of secondary metabolites with interesting bioactive properties as well as enzymes with potential biotechnological applications. However, at genetic level, the study of these fungi has been hindered b...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02675

    authors: Díaz A,Villanueva P,Oliva V,Gil-Durán C,Fierro F,Chávez R,Vaca I

    更新日期:2019-11-22 00:00:00