Molecular typing of antibiotic-resistant Staphylococcus aureus in Nigeria.

Abstract:

BACKGROUND:Antibiotic-resistant Staphylococcus aureus including methicillin-resistant strains (MRSA) are a major concern in densely populated urban areas. Initial studies of S. aureus in Nigeria indicated existence of antibiotic-resistant S. aureus strains in clinical and community settings. METHODS:73 biological samples (40 throat, 23 nasal, 10 wound) were collected from patients and healthcare workers in three populations in Nigeria: Lagos University Teaching Hospital, Nigerian Institute of Medical Research, and Owerri General Hospital. RESULTS:S. aureus was isolated from 38 of 73 samples (52%). Of the 38 S. aureus samples, 9 (24%) carried the Panton-Valentine leukocidin gene (PVL) while 16 (42%) possessed methicillin resistance genes (mecA). Antibiotic susceptibility profiles indicated resistance to several broad-spectrum antibiotics. CONCLUSION:Antibiotic-resistant S. aureus isolates were recovered from clinical and community settings in Nigeria. Insight about S. aureus in Nigeria may be used to improve antibiotic prescription methods and minimize the spread of antibiotic-resistant organisms in highly populated urban communities similar to Lagos, Nigeria.

journal_name

J Infect Public Health

authors

O'Malley SM,Emele FE,Nwaokorie FO,Idika N,Umeizudike AK,Emeka-Nwabunnia I,Hanson BM,Nair R,Wardyn SE,Smith TC

doi

10.1016/j.jiph.2014.08.001

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

187-93

issue

2

eissn

1876-0341

issn

1876-035X

pii

S1876-0341(14)00139-7

journal_volume

8

pub_type

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