Single administration of vildagliptin attenuates postprandial hypertriglyceridemia and endothelial dysfunction in normoglycemic individuals.

abstract：:Here, we present a case of post-operative liver metastases from pancreatic head cancer in a patient with leukocytopenia, who was safely treated by hepatic arterial infusion (HAI) chemotherapy consisting of gemcitabine and 5-FU. The patient was a 61-year-old woman who underwent pancreaticoduodenectomy for pancreatic he...

journal_title：Experimental and therapeutic medicine

authors： Tajima H,Ohta T,Kitagawa H,Sakai S,Makino I,Hayashi H,Nakagawara H,Onishi I,Takamura H,Ninomiya I,Fushida S,Tani T,Fujimura T,Kayahara M,Koda W,Minami T,Ryu Y,Sanada J,Matsui O

更新日期：2010-11-01 00:00:00

abstract：:MicroRNA-155 (miR-155) is overexpressed in numerous human cancer types and has an oncogenic role. Previous study has revealed that miR-155 serves an important role in the progression of clear-cell renal cell carcinoma (ccRCC); however, the underlying mechanism was not completely clarified. The present study aimed to i...

journal_title：Experimental and therapeutic medicine

authors： Ji H,Tian D,Zhang B,Zhang Y,Yan D,Wu S

更新日期：2017-05-01 00:00:00

abstract：:Clinical efficacy of microvascular decompression (MVD) combined with percutaneous stereotactic radiofrequency rhizotomy (PSR) in the treatment of primary trigeminal neuralgia was investigated. The medical records of 141 patients with primary trigeminal neuralgia admitted to Shandong Provincial Hospital from May 2011 t...

journal_title：Experimental and therapeutic medicine

authors： Zhao G,Sun X,Zhang Z,Yang H,Zheng X,Feng B

更新日期：2020-08-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial proliferation and inflammation. Intra-articular corticosteroid injections are commonly used for the treatment of arthritis affecting one or two joints. Although corticosteroid injections are fast-acting, repeated usage can result in se...

journal_title：Experimental and therapeutic medicine

authors： Cho HK,Park GY,Sung WJ,Kawk SG,Jung WB

更新日期：2020-11-01 00:00:00

abstract：:Effects of ropivacaine at different concentrations on intrapartum fever, interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in parturient with epidural labor analgesia were compared to provide reference for the rational selection of anesthetics in clinic. Medical records of 198 cases of primi-paras admitted to t...

journal_title：Experimental and therapeutic medicine

authors： Zhou X,Li J,Deng S,Xu Z,Liu Z

更新日期：2019-03-01 00:00:00

abstract：:The aim of the present study was to determine the preventive effect of the traditional Chinese medicine, Dendrobium candidum Wall ex Lindl. (D. candidum), on CCl4-induced hepatic damage in mice. The CCl4-induced hepatic damage mice were treated with D. candidum, and the serum levels of aspartate aminotransferase (AST)...

journal_title：Experimental and therapeutic medicine

authors： Li GJ,Sun P,Wang Q,Qian Y,Zhu K,Zhao X

更新日期：2014-09-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a progressive disorder of unknown etiology that predominantly affects the lungs, and the resulting respiratory failure can be fatal. Extrapulmonary LAM is a rare disease that often occurs concurrently with pulmonary LAM. Usually, extrapulmonary LAM presents as a localized, well-circum...

journal_title：Experimental and therapeutic medicine

authors： Fu W,Li Y,Li H,Yang P,Xing X

更新日期：2016-09-01 00:00:00

abstract：:The purpose of the present study was to assess the effects of single-session dietary counseling on salt restriction in Japanese cardiology outpatients as assessed using spot urine measurements. A total of 72 patients (73±11 years old, including 30 females) who visited a cardiology outpatient clinic and had a salt inta...

journal_title：Experimental and therapeutic medicine

authors： Yamasaki T,Sadanaga T,Hirota S

更新日期：2015-07-01 00:00:00

abstract：:Pelvic organ prolapse (POP) is a common and distressing health problem in adult women, but the pathophysiological mechanism is yet to be fully elucidated. Previous studies have indicated that oxidative stress may be associated with POP. Thus, the aim of the present study was to investigate the oxidative status of pelv...

journal_title：Experimental and therapeutic medicine

authors： Fang G,Hong L,Liu C,Yang Q,Zhang Q,Li Y,Li B,Wu D,Wu W,Shi H

更新日期：2018-10-01 00:00:00

abstract：:Schwann cell proliferation and differentiation is critical for the remyelination of injured peripheral nerves. Ferulic acid (FA) is a widely used antioxidant agent with neuroprotective properties. However, the potentially beneficial effects of FA on Schwann cells are unknown. Therefore, the present study was designed ...

journal_title：Experimental and therapeutic medicine

authors： Zhu X,Li K,Guo X,Wang J,Xiang Y

更新日期：2016-09-01 00:00:00

abstract：:This study aimed to investigate the correlations between the detection rate of mural coronary artery (MCA) by 128-slice CT and the MCA compression extent in systole with myocardial bridge (MB) length and thickness. A retrospective analysis was conducted for 580 patients receiving multislicespiral CT coronary angiograp...

journal_title：Experimental and therapeutic medicine

authors： Niu YJ,Zhang XL,Cao AD,Leng B

更新日期：2013-03-01 00:00:00

abstract：:Application value of the minimally invasive puncture and small bone window craniotomy in hypertensive intracerebral hemorrhage was investigated to explore the effects of the above treatment methods on motor-evoked potentials (MEPs) and postoperative rehemorrhage. Patients with hypertensive intracerebral hemorrhage who...

journal_title：Experimental and therapeutic medicine

authors： Luan L,Li M,Sui H,Li G,Pan W

更新日期：2019-02-01 00:00:00

abstract：:An increasing number of cancer patients receive outpatient chemotherapy as an alternative to inpatient chemotherapy. The aim of this study was to investigate whether quality of life (QOL) during outpatient chemotherapy was better than QOL prior to hospital discharge, and to explore possible related factors prior to ho...

journal_title：Experimental and therapeutic medicine

authors： Matsuda A,Kobayashi M,Sakakibara Y,Tamaoka M,Furuiye M,Inase N,Matsushima E

更新日期：2011-03-01 00:00:00

abstract：:The aim of this study was to explore the use of urantide as an antagonist of the urotensin II (UII) receptor, G protein-coupled receptor 14 (GPR14), to protect against atherosclerosis (AS) in rats. The AS rat model was induced by an intraperitoneal injection of vitamin D3 (VD3) into rats fed with a high-fat diet for f...

journal_title：Experimental and therapeutic medicine

authors： Zhao J,Yu QX,Kong W,Gao HC,Sun B,Xie YQ,Ren LQ

更新日期：2013-06-01 00:00:00

abstract：:This study was designed to investigate the correlation of vitamin D receptor (VDR) gene polymorphism with bronchial asthma in children. Seventy patients admitted to Daqing Longnan Hospital and diagnosed as bronchial asthma for the first time from April 2015 to May 2017 were selected as observation group. Patients rece...

journal_title：Experimental and therapeutic medicine

authors： Hou C,Zhu X,Chang X

更新日期：2018-03-01 00:00:00

abstract：:A previous study by our group showed that a 44-amino-acid fragment of pigment epithelium-derived factor (PEDF) facilitated corneal epithelial wound healing. In the present study this fragment was shortened to obtain peptides of 18, 20 and 29 amino acids in length, and their promoting effects on the healing of full-thi...

journal_title：Experimental and therapeutic medicine

authors： Tsai SH,Tsao LP,Chang SH,Ho TC,Tung KY,Wu AC,Tsao YP

更新日期：2017-11-01 00:00:00

abstract：:The aim of the present study was to investigate whether chronic administration of basic fibroblast growth factor (bFGF) following angioplasty in a dog model of atherosclerotic iliac stenosis may restore endothelium function and prevent restenosis (RS). In total, 40 dogs with atherosclerotic stenosis of the right iliac...

journal_title：Experimental and therapeutic medicine

authors： Ran F,Liu C,Liu Z,Shang T,Zhou M,Qiao T

更新日期：2014-05-01 00:00:00

abstract：:In patients undergoing off-pump coronary artery bypass surgery (OPCAB), it is important to attenuate myocardium injury during the surgery. The present study aimed to observe the cardioprotection induced by sevoflurane induction and maintenance compared with propofol intravenous anesthesia, and to detect its potential ...

journal_title：Experimental and therapeutic medicine

authors： Liu X,Liu X,Wang R,Luo H,Qin G,Wang LU,Ye Z,Guo Q,Wang E

更新日期：2016-06-01 00:00:00

abstract：:Anti-mitochondrial M2 antibody (AMA-M2) is specific to primary biliary cirrhosis (PBC), but can also be found in certain patients with autoimmune hepatitis (AIH). Effective methods of differentiating between PBC and AIH are required, as their clinical course and management are different. Titers of AMA-M2 were analyzed...

journal_title：Experimental and therapeutic medicine

authors： Tomizawa M,Shinozaki F,Fugo K,Motoyoshi Y,Sugiyama T,Yamamoto S,Kishimoto T,Ishige N

更新日期：2015-10-01 00:00:00

abstract：:The present study was designed to test the hypothesis that butylphthalide protects the brain of Alzheimer's disease (AD) model rats by inhibiting apoptosis. Ninety Sprague-Dawley rats were randomly divided into drug, control and blank groups of 30 rats in each. The rats in the drug and control groups were treated to i...

journal_title：Experimental and therapeutic medicine

authors： Song FX,Wang L,Liu H,Wang YL,Zou Y

更新日期：2017-06-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small, non-coding RNAs that are key regulators of gene expression by directly binding to the 3'-untranslated region of their target mRNAs, resulting in translational repression or degradation of mRNA. It has been demonstrated that miRNAs have key roles in a variety of human malignancies, includi...

journal_title：Experimental and therapeutic medicine

authors： He Y,Yu B

更新日期：2017-05-01 00:00:00

abstract：:The universal endocrine pathological state affecting young individuals and adults is type 2 diabetes mellitus, which has seen a significant increase in the last 30 years, particularly in children. Genetic and evnironmental factors are the causative agents for this pathological state in children. This rapid and wide sp...

journal_title：Experimental and therapeutic medicine

authors： Xue Y,Gao M,Gao Y

更新日期：2016-10-01 00:00:00

abstract：:The present study aimed to investigate changes in the levels of metabolites and appetite control factors caused by different dietary interventions in Sprague Dawley (SD) rats. A total of 35 male SD rats were weaned and immediately randomly assigned to five groups. The control group was given ad libitum access to a nor...

journal_title：Experimental and therapeutic medicine

authors： Lin B,Liu Y,Zhang W,Zou W

更新日期：2020-09-01 00:00:00

abstract：:The abnormal expression of miRNAs (miRs) has previously been reported in respiratory syncytial virus (RSV) disease. However, to the best of our knowledge, the expression of miR-140-5p in patients with an RSV infection has never been explored. Reverse transcription-quantitative polymerase chain reaction was performed t...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Shao L

更新日期：2018-08-01 00:00:00

abstract：:3-Hydroxy-3-methylglutaric aciduria (3-HMG, OMIN 246450) is a rare autosomal recessive metabolic disorder caused by a deficiency of 3-hydroxy-3-methylglutaryl-CoA lyase, a key enzyme in leucine metabolism and ketone body synthesis. Acute episodes of 3-HMG may be triggered by fasting or infection, and symptoms include ...

journal_title：Experimental and therapeutic medicine

authors： Hao X,Wang J,Liu S,Chen Y,Zhang Y,Hao Y

更新日期：2016-06-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2017.4943.]. ...

journal_title：Experimental and therapeutic medicine

authors： Li S,Xu G,Gao F,Bi J,Huo R

更新日期：2018-10-01 00:00:00

abstract：:Primary lung enteric adenocarcinoma is a rare type of invasive lung carcinoma. Its morphology and immunohistochemistry are those of colorectal carcinoma, but there is no associated primary colorectal carcinoma. The present study describes the case of a 53-year-old female who presented with an irritating cough and a ma...

journal_title：Experimental and therapeutic medicine

authors： Lin LI,Xu CW,Zhang BO,Liu RR,Ge FJ,Zhao CH,Jia RU,Qin QH,Stojsic J,Wang Y,Xu JM

更新日期：2016-01-01 00:00:00

abstract：:The DNA methylation inhibitor 5-aza-2'-deoxycytidine (5-aza-CdR) is widely used as an anticancer drug for the treatment of leukemia and solid tumors. Gastric cancer (GC) patients who were positive for caudal type homeobox transcription factor 2 (CDX2) expression showed a higher survival rate compared with those who we...

journal_title：Experimental and therapeutic medicine

authors： Zhang JF,Zhang JG,Kuai XL,Zhang H,Jiang W,Ding WF,Li ZL,Zhu HJ,Mao ZB

更新日期：2013-03-01 00:00:00

abstract：:Compared with traditional imaging techniques, multimodal imaging obtains more accurate images that may increase disease detection rates. The present study prepared stromal cell-derived factor 1 (SDF-1)-loaded, targeted nanoparticles coated with iron (II,III) oxide and perfluorohexane (PFH) to be used as polymer-shelle...

journal_title：Experimental and therapeutic medicine

authors： Wang F,Wang Z,Pang L,Wan S,Qiu L

更新日期：2020-09-01 00:00:00

abstract：:Stromal cell-derived growth factor (SDF)-1α acts as a ligand to C-X-C chemokine receptors 4 (CXCR4) and 7 (CXCR7), which are involved in the formation of choroidal neovascularization. Previous studies have demonstrated crosstalk between the platelet-derived growth factor (PDGF)-BB/PDGF receptor (PDGFR)-β and SDF-1α/CX...

journal_title：Experimental and therapeutic medicine

authors： Xiang DN,Feng YF,Wang J,Zhang X,Shen JJ,Zou R,Yuan YZ

更新日期：2019-11-01 00:00:00