Role of diet on intestinal metabolites and appetite control factors in SD rats.

abstract：:The present study reported a case of portopulmonary hypertension (POPH) that was secondary to underlying liver cirrhosis in a 58-year-old woman, who was successfully treated with low-dose tolvaptan. The patient had suffered from refractory peripheral edema and electrolyte abnormalities, including severe hypokalemia, u...

journal_title：Experimental and therapeutic medicine

authors： Ogihara Y,Yamada N,Dohi K,Matsuda A,Ota S,Ishikura K,Nakamura M,Ito M

更新日期：2017-01-01 00:00:00

abstract：:The hypoxia-reoxygenation process of obstructive sleep apnea (OSA) may cause oxidative stress injury of the kidney, but the molecular mechanisms are not clear. The present study aimed to investigate whether high mobility group box 1 protein (HMGB1) and its subsequent inflammatory pathway served a role in kidney injury...

journal_title：Experimental and therapeutic medicine

authors： Zhang C,Dong H,Chen F,Wang Y,Ma J,Wang G

更新日期：2019-01-01 00:00:00

abstract：:The objective of the study was to evaluate the effect of abdominal fat proportion on hepatic computed tomography (CT) enhancement. CT data for 87 patients (47 men, mean age 55.09±13.27 years; 40 women, mean age 60.43±11.29 years) were analyzed by linear regression to assess the association of patient age and abdominal...

journal_title：Experimental and therapeutic medicine

authors： Zhang Q,Guo MJ,Wu YF

更新日期：2015-07-01 00:00:00

abstract：:The aim of this study was to determine whether the vascular endothelial growth factor (VEGF) +936C/T polymorphism confers susceptibility to gastric cancer (GC) by conducting a meta-analysis. Publications addressing the association between the VEGF +936C/T polymorphism and GC risk were selected from the Pubmed, Embase ...

journal_title：Experimental and therapeutic medicine

authors： Zhou LP,Luan H,Dong XH,Jin GJ,Man DL,Shang H

更新日期：2011-09-01 00:00:00

abstract：:The US Food and Drug Administration approved thalidomide and its analogues for the treatment of erythema nodosum leprosum, in spite of the notoriety of reports of severe birth defects in the middle of the last century. As immunomodulatory drugs, thalidomide and its analogues have been used to effectively treat various...

journal_title：Experimental and therapeutic medicine

authors： Liu T,Guo F,Zhu X,He X,Xie L

更新日期：2017-12-01 00:00:00

abstract：:Subclinical hypothyroidism (SCH) is becoming a global health problem due to its increasing prevalence and potential adverse effects, including cardiovascular diseases and nonalcoholic fatty liver disease (NAFLD). However, the association between SCH and NAFLD remains controversial. MicroRNAs (miRNAs/miRs) have been re...

journal_title：Experimental and therapeutic medicine

authors： Zhang L,Wu K,Bo T,Zhou L,Gao L,Zhou X,Chen W

更新日期：2020-02-01 00:00:00

abstract：:The aim of this study was to explore the etiology and diagnosis of multiple intracranial hemorrhages (ICHs) following severe burns, with a retrospective review of 16 cases of severe burns further complicated by multiple ICHs. Using cranial CT scans of the brains, we identified that all patients presented with low plat...

journal_title：Experimental and therapeutic medicine

authors： Zhou J,Liu J,Luo C,Hu F,Liu R,Chen Z,Chen Y,Xiong W,Xie J,He Q,Yin C,Wang S,Zhang Y,Zeng S

更新日期：2013-07-01 00:00:00

abstract：:Organic cation transporter member 2 (OCT2) is an N-glycosylated transporter that has been shown to be closely associated with the transport of antitumor drugs. Oxaliplatin, a platinum-based drug, is used for the chemotherapy of colorectal cancer (CRC). However, oxaliplatin resistance is a major challenge in the treatm...

journal_title：Experimental and therapeutic medicine

authors： Cong X,Liu X,Dong X,Fang S,Sun Z,Fan J

更新日期：2021-02-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2019.8114.]. ...

journal_title：Experimental and therapeutic medicine

authors： Fang L,Xu Z,Lu J,Hong L,Qiao S,Liu L,An J

更新日期：2021-02-01 00:00:00

abstract：:On December 31, 2019, the first case of a novel coronavirus infection was reported in Wuhan, China. The ongoing outbreak of the 2019 novel coronavirus (2019-nCoV) has caused immense global concern. According to the recommendations of the International Health Regulations Emergency Committee and the facts and cases that...

journal_title：Experimental and therapeutic medicine

authors： Feng X,Xie X,Song S,Chen W,Bian H,Rui F,Zhu Q,Ren W,Qin C,Qi J

更新日期：2021-01-01 00:00:00

abstract：:Lentinus (L.) edodes (shiitake mushroom) is used as a traditional medicine in Asia. One of the components of L. edodes, eritadenine (an adenosine analog alkaloid), has been shown to reduce cholesterol levels. The hypocholesterolemic action of eritadenine appears to be achieved through the modification of hepatic phosp...

journal_title：Experimental and therapeutic medicine

authors： Yang H,Hwang I,Kim S,Hong EJ,Jeung EB

更新日期：2013-12-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) has become a significant public health risk. Long non-coding RNAs (lncRNAs) have been identified as important factors involved in the proliferation, apoptosis and inflammatory cytokine expression of lung cells. Peripheral blood samples from 66 subjects (18 non-smokers, 24 s...

journal_title：Experimental and therapeutic medicine

authors： Lei Z,Guo H,Zou S,Jiang J,Kui Y,Song J

更新日期：2021-01-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is the most common congenital infection worldwide, and remains a significant cause of the neurological deficiency and sensory deafness in developed countries. Maternal primary infection, reactivation or reinfection during pregnancy may lead to fetal infection and congenital CMV syndrome...

journal_title：Experimental and therapeutic medicine

authors： Gorun F,Motoi S,Malita D,Navolan DB,Nemescu D,Olariu TR,Craina M,Vilibic-Cavlek T,Ciohat I,Boda D,Dobrescu A

更新日期：2020-09-01 00:00:00

abstract：:Atherosclerosis is the leading cause of death from vascular diseases worldwide, and endothelial cell (EC) dysfunction is the key cause of atherosclerosis. miR-155 was found to induce endothelial injury and to trigger atherosclerosis. In addition, brain and muscle ARNT-like protein-1 (Bmal1) has been found to be closel...

journal_title：Experimental and therapeutic medicine

authors： Liang S,Hu J,Zhang A,Li F,Li X

更新日期：2020-12-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been indicated to serve critical roles in cancer development and progression. Long intergenic non-protein coding RNA 70 (LINC00707) was recently reported to be an oncogene involved in the tumorigenesis of several types of human cancer. However, the clinical role, biological function...

journal_title：Experimental and therapeutic medicine

authors： Wang H,Luan H,Zhan T,Liu X,Song J,Dai H

更新日期：2020-02-01 00:00:00

abstract：:Polygoni Multiflori Radix is a traditional Chinese medicine used clinically to support the functions of the liver and kidneys and to treatment hyperlipidemia. In previous studies, an effective fraction, rich in 2,3,5,4'-tetrahydroxy stilbene-2-O-β-D-glucoside (TSG), was separated from Polygoni Multiflori Radix and dem...

journal_title：Experimental and therapeutic medicine

authors： Lou Z,Xia B,Su J,Yu J,Yan M,Huang Y,Lv G

更新日期：2017-11-01 00:00:00

abstract：:Hyperlipidemia is a risk factor of kidney damage that can lead to chronic kidney disease. Studies have shown that exercise reduces kidney damage; however, the specific mechanisms underlying the protective effects of exercise remain unclear. For 12 weeks, 8-week-old male apolipoprotein E-deficient (ApoE-/-) mice were r...

journal_title：Experimental and therapeutic medicine

authors： Qian C,Yang Q,Guo L,Zhu H,You X,Liu H,Sun Y

更新日期：2021-02-01 00:00:00

abstract：:Evaluation of multi-slice CT angiography (MSCTA) and digital subtraction angiography (DSA) was made through the comparison of the two methods in detecting the blood supply of meningiomas, providing further clues for the improved application of MSCTA and DSA in the blood supply of meningiomas. In this study, 20 patient...

journal_title：Experimental and therapeutic medicine

authors： Han X,Zhan Y,Chen J

更新日期：2012-01-01 00:00:00

abstract：:Systemic therapy in patients with concurrent psoriasis and chronic hepatitis B is a challenging task for both dermatologists and gastroenterologists since there is a high risk for hepatitis B virus (HBV) reactivation and hepatic toxicity under biological therapy. The therapeutic management of a patient with psoriasis ...

journal_title：Experimental and therapeutic medicine

authors： Raducan A,Bucur S,Caruntu C,Constantin T,Nita IE,Manolache N,Constantin MM

更新日期：2019-08-01 00:00:00

abstract：:The present study aimed to evaluate the impact of small interfering RNA (siRNA) targeting of the survivin gene in human tumor cells and the effect of decreased survivin expression on the proliferation and apoptosis of tumor cells. Human tumor cell lines (MSA-MB-231, SGC-7901, HeLa, A549, SK-OV-3 and Raji, PC-3) were c...

journal_title：Experimental and therapeutic medicine

authors： Zhang Z,Wang T,Liu Z,Tang S,Yue M,Feng S,Hu M,Xuan L,Chen Y

更新日期：2017-07-01 00:00:00

abstract：:Electroacupuncture (EA) may stimulate neurogenesis in animal models of ischemic stroke; however, the associated mechanisms are not clear. The present study aimed to evaluate the neurogenesis efficacy of EA on ischemic stroke and the underlying associated mechanisms. A model of middle cerebral artery occlusion (MCAO) w...

journal_title：Experimental and therapeutic medicine

authors： Tan F,Wang J,Liu JX,Wang C,Li M,Gu Y

更新日期：2018-12-01 00:00:00

abstract：:It has been widely reported that the serum anion gap is significantly associated with mortality in intensive care unit (ICU); however, it remains unknown whether the association is present in aortic aneurysm (AA) patients. The present study aimed to investigate the association between the admission serum anion gap and...

journal_title：Experimental and therapeutic medicine

authors： Chen Q,Chen Q,Li L,Lin X,Chang SI,Li Y,Tian Z,Liu W,Huang K

更新日期：2018-09-01 00:00:00

abstract：:Effects of propofol, midazolam and dexmedetomidine on patients with sepsis in intensive care unit (ICU) and on arterial blood gas (ABG) were studied. In total 429 ICU patients with sepsis, admitted to Renji Hospital, School of Medicine, Shanghai Jiaotong University from May 2015 to January 2019, were selected as resea...

journal_title：Experimental and therapeutic medicine

authors： Ding J,Chen Y,Gao Y

更新日期：2019-12-01 00:00:00

abstract：:Therapy using acellular spinal cord (ASC) scaffolds seeded with bone marrow stromal cells (BMSCs) has previously been shown to restore function of the damaged spinal cord and improve functional recovery in a rat model of acute hemisected spinal cord injury (SCI). The aim of the present study was to determine whether B...

journal_title：Experimental and therapeutic medicine

authors： Wang YH,Chen J,Zhou J,Nong F,Lv JH,Liu J

更新日期：2017-01-01 00:00:00

abstract：:Uterine carcinosarcoma (UCS) is a rare but very aggressive cancer of the female reproductive tract with an extremely poor prognosis. With the goal of understanding the role of microRNA (miRNA) dysregulation in these tumors, we profiled the expression of 667 human miRNAs in a panel of eight UCS patients and five benign...

journal_title：Experimental and therapeutic medicine

authors： Devor EJ,DE Mik JN,Ramachandran S,Goodheart MJ,Leslie KK

更新日期：2012-04-01 00:00:00

abstract：:The present study evaluated the effects of calcitonin gene-related peptide (CGRP) on bone marrow mesenchymal stem cells (BMMSCs) in vitro and in a rat model of mandibular distraction osteogenesis (MDO). Rat BMMSCs were isolated then treated with CGRP or CGRP antagonist (CGRP8-37). The proliferation and migration abili...

journal_title：Experimental and therapeutic medicine

authors： Jia S,Zhang SJ,Wang XD,Yang ZH,Sun YN,Gupta A,Hou R,Lei DL,Hu KJ,Ye WM,Wang L

更新日期：2019-08-01 00:00:00

abstract：:Synovitis, acne, palmoplantar pustulosis, hyperostosis and osteitis syndrome (SAPHO) is a rare syndrome that affects the skin, bones and joints. Diagnosis of SAPHO syndrome is established on clinical appearance and imaging features. The present case report described the imaging features of three cases of SAPHO with st...

journal_title：Experimental and therapeutic medicine

authors： Duan N,Chen X,Liu Y,Wang J,Wang Z

更新日期：2016-10-01 00:00:00

abstract：:The programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) signaling pathway is a negative regulatory mechanism that inhibits T cell proliferation and cytokine production. Soluble PD-1 (sPD-1) and soluble PD-L1 (sPD-L1), are also involved in regulation of the PD-1/PD-L1 signaling pathway. In the present study, the expression l...

journal_title：Experimental and therapeutic medicine

authors： Li Y,Xiao Y,Su M,Zhang R,Ding J,Hao X,Ma Y

更新日期：2016-01-01 00:00:00

abstract：:Eosinophilia has been implicated in the pathophysiology of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, the role of eosinophil activation in the development of AECOPD remains unclear. In the present study, the reliability of plasma levels of eosinophil activation markers, including eo...

journal_title：Experimental and therapeutic medicine

authors： Yang QF,Lu TT,Shu CM,Feng LF,Chang HT,Ji QY

更新日期：2017-10-01 00:00:00

abstract：:The application of biomarkers in melanoma prognosis has been well recognized. However the ability of a single biomarker to predict melanoma patient outcome is usually limited. We previously examined the expression of ten biomarkers (Bim, BRG1, BRMS1, CTHRC1, ING4, NQO1, NF-κB-p50, PUMA, SNF5 and SOX4) in melanomas. To...

journal_title：Experimental and therapeutic medicine

authors： Li J,Zhang Z,Li G

更新日期：2011-01-01 00:00:00