Saliva with reduced calcium and phosphorous concentrations: Effect on erosion dental lesions.

Abstract:

OBJECTIVES:To investigate whether saliva formulations with reduced calcium (Ca) and inorganic phosphorous (Pi) concentration would affect dental erosion caused by hydrochloric acid (HCl). METHODS:Enamel and root dentine bovine slabs were embedded, polished, and measured for surface Knoop microhardness (SMH). After reference areas were created, specimens were exposed to HCl solution (0.01 M; pH 2; 120 s) and immersed in artificial salivas (6 hr) containing three different Ca/Pi concentrations (n = 15), which simulate serum conditions of normo-, mild, or severe hypocalcemia. The control group was immersed in Ca/Pi-free saliva. The study protocol was carried out 2×/day for 5 days. Surface loss of enamel and root dentine was assessed using an optical profilometer, and SMH was remeasured for enamel. RESULTS:One-way analysis of variance (p < .001) and Tukey's test showed that enamel loss in groups subjected to artificial salivas that simulated mild or severe hypocalcemia did not differ from that resembling normocalcemia. %SMH was lower when saliva was mildly and normally concentrated in Ca/Pi (p < .001). Root dentine loss was higher in saliva simulating severe hypocalcemia than in those referring to mild, hypo-, and normocalcemia. CONCLUSIONS:Depending on the dental substrate, salivary formulations resembling serum hypocalcemia affected surface loss due to erosion and rehardening thereof.

journal_name

Oral Dis

journal_title

Oral diseases

authors

Denucci GC,Mantilla TF,Amaral F,Basting RT,França F,Turssi CP

doi

10.1111/odi.12843

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

957-963

issue

6

eissn

1354-523X

issn

1601-0825

journal_volume

24

pub_type

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