Oral lichen planus: a preliminary clinical study on treatment with tazarotene.

abstract：OBJECTIVES:Cyclosporine A (CsA) is used as an immunosuppressive agent and its prominent side effect is the induction of gingival overgrowth. Type I plasminogen activator inhibitor (PAI-1) has shown to play an important role in CsA-induced gingival overgrowth. However, little is known about whether factors can modulate ...

journal_title：Oral diseases

authors： Ho YC,Lin HJ,Tsai CH,Chang YC

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:To assess the effects of periodontitis on renal interstitial fibrosis in a mouse model. MATERIALS AND METHODS:Thirty C57BL/6 male mice were divided into control, periodontitis (PD), unilateral ureteral ligation (UUO) and PD+UUO groups. Unilateral ureteral ligation was performed 6 days after periodontitis. A...

journal_title：Oral diseases

authors： Bi C,Han XL,Li XZ,Sun JY,Liu Y,Duan SZ,Lu HX

更新日期：2020-12-31 00:00:00

abstract：BACKGROUND:Tumour budding (B) and depth of invasion (D) have both been reported as promising prognostic markers in oral squamous cell carcinoma (OSCC). This meta-analysis assessed the prognostic value of the tumour budding and depth of invasion combination (BD model) in OSCC. METHODS:Databases including Ovid MEDLINE, ...

journal_title：Oral diseases

authors： Wahab A,Onkamo O,Pirinen M,Almangush A,Salo T

更新日期：2020-10-08 00:00:00

abstract：:The aim of this article is to review the clinical, pathophysiological, and therapeutic aspects of traumatically induced trigeminal nerve pain. We introduce a new and, in our view, more accurate terminology: peripheral painful traumatic trigeminal neuropathy (PPTTN) to define this patient group. The proposed pathophysi...

journal_title：Oral diseases

authors： Benoliel R,Kahn J,Eliav E

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to determine whether the expression levels of specific circulating serum microRNAs (miRNAs) are associated with mandibular prognathism (MP). METHODS:Sixty subjects in the early permanent dentition stage and 23 in the mixed dentition stage with MP were identified. Sixty-eight normal ...

journal_title：Oral diseases

authors： Gu Y,Zhang Y,Zhao C,Pan Y,Smales RJ,Wang H,Ni Y,Zhang H,Ni J,Ma J,Wang L

更新日期：2014-01-01 00:00:00

abstract：:The connective tissues of the gingiva and periodontal ligament share a common embryonic development from cells of the cranial neural crest. This review paper describes the relationship of these tissues in tooth germ initiation, development and eruption. ...

journal_title：Oral diseases

authors： Palmer RM,Lubbock MJ

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVES:Toll-like receptor 4 (TLR4) is abnormally expressed in oral cancer tissues and promotes cancer cell invasion. The purpose of this study was to clarify the mechanism by which autophagy regulates oral cancer invasion through the TLR4-NF-κB pathway. SUBJECTS AND METHODS:We examined TLR4 expression in oral canc...

journal_title：Oral diseases

authors： Kong Q,Liang Y,He Q,You Y,Wu L,Liang L,Liang J

更新日期：2020-04-14 00:00:00

abstract：OBJECTIVE: This study is aimed to investigate the association between OLP susceptibility and clinical type in the Thai population and three polymorphisms within the promoter region of the TNF-α at positions -863, -308 and -238 which have putative functional significances. MATERIALS AND METHODS: Genomic DNA from 75 Tha...

journal_title：Oral diseases

authors： Kimkong I,Hirankarn N,Nakkuntod J,Kitkumthorn N

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Oral lichen planus is a chronic, T-cell-mediated, inflammatory disease that affects the oral cavity. The oral lichen planus pathogenesis is still unclear, however, the main evidence is that the mechanisms of activation of different T lymphocyte pathway induce apoptosis with an increase in Th1 and Th17 subtyp...

journal_title：Oral diseases

authors： Souza MM,Florezi GP,Nico M,de Paula F,Paula FM,Lourenço SV

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To investigate the sex differences in clinical features, including salivary flow rate, psychological distress and hypothalamic-pituitary-adrenal axis response and their inter-relationships in patients with burning mouth syndrome. SUBJECTS AND METHODS:Eighteen men and 37 postmenopausal women with burning mout...

journal_title：Oral diseases

authors： Lee YH,An JS,Chon S

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the correlation between the number of FOXP3(+) T cell in lesions and the disease activity of patients with oral lichen planus (OLP). MATERIALS AND METHODS:The expression of FOXP3 was investigated using immunohistochemical staining and real-time RT-PCR in 23 OLP lesions ...

journal_title：Oral diseases

authors： Tao XA,Xia J,Chen XB,Wang H,Dai YH,Rhodus NL,Cheng B

更新日期：2010-01-01 00:00:00

abstract：:Periodontal tissues are constantly exposed to microbial stimuli. The equilibrium between microbes and host defense system helps maintain the homeostasis in the periodontal microenvironment. Growth of pathogenic bacteria in dental biofilms may induce proinflammatory cytokine production to recruit sentinel cells, mainly...

journal_title：Oral diseases

authors： Li J,Ke X,Yan F,Lei L,Li H

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To compare the frequency of gene expression of matrix metalloproteinases (MMP) stromelysins -1, -2 and -3 (MMP-3, -10, and -11), matrilysin (MMP-7), MTI-MMP (MMP-14), and of TIMPs (Tissue Inhibitors of MMPs) -1, -2, -3 and -4 in head and neck squamous cell carcinomas with those of matched adjacent normal tiss...

journal_title：Oral diseases

authors： Birkedal-Hansen B,Pavelic ZP,Gluckman JL,Stambrook P,Li YQ,Stetler-Stevenson WG

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To assess the health-related quality of life (HRQOL) of patients complaining of halitosis at their first visit and at a later time when their complaint had diminished following therapy, using a self-administered questionnaire, the Medical Outcome Study Short Form-36 (SF-36). The aim of this study was to exami...

journal_title：Oral diseases

authors： Kishi M,Abe A,Yonemitsu M

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:To investigate whether saliva formulations with reduced calcium (Ca) and inorganic phosphorous (Pi) concentration would affect dental erosion caused by hydrochloric acid (HCl). METHODS:Enamel and root dentine bovine slabs were embedded, polished, and measured for surface Knoop microhardness (SMH). After ref...

journal_title：Oral diseases

authors： Denucci GC,Mantilla TF,Amaral F,Basting RT,França F,Turssi CP

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:This study aimed to analyse Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) viral loads in symptomatic and asymptomatic apical periodontitis lesions, to determine levels of TNF-α, IL-1β and IL-6 in these lesions and to investigate a possible correlation between herpesviral copy numbers and levels o...

journal_title：Oral diseases

authors： Jakovljevic A,Knezevic A,Nikolic N,Soldatovic I,Jovanovic T,Milasin J,Andric M

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To obtain baseline data on angular cheilitis in Southern Chinese. DESIGN:A cross-sectional investigation of the clinical, microbiological and ultrastructural features of the condition. SUBJECTS AND METHOD:Thirty six Chinese adults with angular cheilitis; 28 controls matched for age and sex, with no inflamma...

journal_title：Oral diseases

authors： Dias AP,Samaranayake LP

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:The aim was to investigate the attitudes of people with HIV infection towards their own dental care provision and the possible implications for future resource allocation. DESIGN:Sixty-nine HIV positive subjects attending support groups in London were interviewed. Past and current dental visiting behaviour,...

journal_title：Oral diseases

authors： Gallagher PD,Gealer M,Birnbaum W

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Orofacial granulomatosis (OFG) is a rare condition characterized by non-caseating granulomas in the orofacial region. Protease-Activated Receptors (PARs) play a role in inflammatory diseases in diverse human tissues. The aim of the study was to investigate the expression of PAR-1, PAR-2, MMP-2, MMP-9, COX-1, ...

journal_title：Oral diseases

authors： Ketabchi S,Massi D,Ficarra G,Rubino I,Franchi A,Paglierani M,Simoni A,Capodiferro S,Favia G,Maiorano E,Tarantini F,Cirino G,Santucci M

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Up to 30% of multiple myeloma (MM) patients have subclinical amyloid deposits. These patients are under-recognized and are more susceptible to drug toxicity, bleeding and death. Early diagnosis and adjustment of treatment are crucial. Biopsies of oral mucosa might be a potentially useful diagnostic tool. The ...

journal_title：Oral diseases

authors： Leiba M,Jarjoura S,Abboud W,Nagler A,Yahalom R,Duek A,Yarom N

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Orofacial clefts (OFCs) are common birth defects that may impose a large burden on the health and psychosocioeconomic well-being of affected individuals and families. This study aims to identify qualitative factors that affect the quality of life (QOL) of family caregivers of children with OFCs. METHODS:A m...

journal_title：Oral diseases

authors： Awoyale T,Onajole AT,Ogunnowo BE,Adeyemo WL,Wanyonyi KL,Butali A

更新日期：2016-03-01 00:00:00

abstract：:Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this condition. In addition to evidence regarding the basic and clinic...

journal_title：Oral diseases

authors： Ceponis P,Keilman C,Guerry C,Freiberger JJ

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:To comparatively assess periodontal status in patients who chew different products and patients who do not have this habit and to assess how this practice interacts with predisposing factors and risk indicators of disease. METHODS:Patients included in the dental care carried out in a rural community in Indi...

journal_title：Oral diseases

authors： Giovannoni ML,Valdivia-Gandur I,Lozano de Luaces V,Varela Véliz H,Balasubbaiah Y,Chimenos-Küstner E

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare viscosity and wettability between animal mucin solutions and human saliva. MATERIALS AND METHODS:Human whole and glandular saliva, porcine gastric mucin, bovine submaxillary mucin, and a mucin-based saliva substitute were used. Viscosity was measured with a cone-and-p...

journal_title：Oral diseases

authors： Park MS,Chung JW,Kim YK,Chung SC,Kho HS

更新日期：2007-03-01 00:00:00

abstract：:Studies of the malignant potential of oral lichen planus (OLP) have been hampered by inconsistencies in the diagnostic criteria used for OLP, the criteria adopted to identify a true case of malignant transformation in OLP, the risk factors for malignant transformation and the optimum management of patients to ensure t...

journal_title：Oral diseases

authors： Gonzalez-Moles MA,Scully C,Gil-Montoya JA

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:This study was designed to establish a rat model of a critical size alveolar bone defect. MATERIALS AND METHODS:Standardized buccal or mesiobuccal alveolar bone defects were made around the right first mandibular molar of 12-week-old rats, and the left was used as a control. Alveolar bone healing was examine...

journal_title：Oral diseases

authors： Ebina H,Hatakeyama J,Onodera M,Honma T,Kamakura S,Shimauchi H,Sasano Y

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Increasing evidence indicates that andrographolide (ADG) exhibits anti-cancer activity against various cancer cell lines. However, its high hydrophobicity and poor bioavailability restrict its clinical application as a chemopreventative agent. Previously, we have shown that ADG-loaded solid lipid nanoparticl...

journal_title：Oral diseases

authors： Li H,Qu X,Qian W,Song Y,Wang C,Liu W

更新日期：2020-12-09 00:00:00

abstract：:As the AIDS pandemic has continued, our understanding of the events that occur during the entry and infection of conventional, susceptible cells has increased dramatically, leading to the development of control therapies for HIV-infected individuals. However, an ongoing hole in our understanding is how HIV crosses the...

journal_title：Oral diseases

authors： Moyes DL,Islam A,Kohli A,Naglik JR

更新日期：2016-04-01 00:00:00

abstract：:The human microbiome consists of all microorganisms occupying the skin, mucous membranes and intestinal tract of the human body. The contact of the mucosal immune system with the human microbiome is a balanced interplay between defence mechanisms of the immune system and symbiotic or pathogenic microbial factors, such...

journal_title：Oral diseases

authors： van der Meulen TA,Harmsen H,Bootsma H,Spijkervet F,Kroese F,Vissink A

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To investigate the matrix metalloproteinase (MMP)-13 expression in associated and non-nevoid basal cell carcinoma syndrome (NBCCS) Odontogenic Keratocysts (OCKs) in order to contribute to a better understanding of the differences in the growth pattern between them. MATERIALS AND METHODS:Thirty-nine paraffin-...

journal_title：Oral diseases

authors： Leonardi R,Matthews JB,Caltabiano R,Greco M,Lombardo C,Loreto C,Santarelli A,Lo Muzio L

更新日期：2010-11-01 00:00:00