Long noncoding RNA GIHCG is a potential diagnostic and prognostic biomarker and therapeutic target for renal cell carcinoma.

abstract：OBJECTIVE:Readmissions to hospital after discharge are considered adverse, serious and costly outcomes. In the last years, two new scores have been proposed to identify patients at high risk of hospital readmission, the HOSPITAL and the Elders Risk Assessment (ERA) indexes. The aim of this study was to evaluate these t...

journal_title：European review for medical and pharmacological sciences

authors： De Giorgi A,Boari B,Tiseo R,López-Soto PJ,Signani F,Gallerani M,Manfredini R,Fabbian F

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:This study aims to illustrate the potential role of MAGI1-IT1 in the progression of non-small cell lung cancer (NSCLC) and the underlying mechanism. PATIENTS AND METHODS:The relative level of MAGI1-IT1 in normal lung tissues and NSCLC tissues was determined. Its level in NSCLC patients with different tumor s...

journal_title：European review for medical and pharmacological sciences

authors： Zhang G,Chen HX,Yang SN,Zhao J

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether hypoxia microenvironment induced hepatocellular carcinoma cells SMMC-7721 epithelial-mesenchymal transition (EMT) and to explore the underlying molecular mechanism. MATERIALS AND METHODS:In this study, SMMC-7721 cells were cultured under normoxia and hypoxia conditions, respectively. R...

journal_title：European review for medical and pharmacological sciences

authors： Zhang XD,Dong XQ,Xu JL,Chen SC,Sun Z

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Osteoradionecrosis (ORN) is a bone aseptic necrosis which develops on post-irradiated bone tissue of patients who underwent radiotherapy for head-neck tumors. The mandible presents a higher risk to develop ORN, if compared to the maxillary bone, due to its lower vascularization. The aim of the present study i...

journal_title：European review for medical and pharmacological sciences

authors： Manzon L,Rossi E,Fratto G

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To investigate the protective role of ulinastatin (UTI) on myocardial ischemia-reperfusion (I/R) injury in rats via endoplasmic reticulum stress (ERS)-induced apoptosis pathway. MATERIALS AND METHODS:A total of 60 rats were randomly divided into normal group (n=20), myocardial I/R model group (model group, n...

journal_title：European review for medical and pharmacological sciences

authors： Lun MH,Jin XY,Wang MY,Cai Z,Du W,Huang ZQ

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:This study aims to investigate whether HOX transcript antisense RNA (HOTAIR) can participate in the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) by regulating the Wnt/β-catenin pathway, thereby participating in the pathogenesis of osteoporosis. PATIENTS AND METHODS:We detected the...

journal_title：European review for medical and pharmacological sciences

authors： Shen JJ,Zhang CH,Chen ZW,Wang ZX,Yang DC,Zhang FL,Feng KH

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Pediatric tuberculosis of the central nervous system (CNS-TB) is a severe form of extrapulmonary TB. It is most common in children between 6 months and 4 years of age. CNS-TB can present as meningitis and/or tuberculoma. In both situations, brain damage results from a cytokine-mediated inflammatory response,...

journal_title：European review for medical and pharmacological sciences

authors： Buonsenso D,Serranti D,Valentini P

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Endothelial dysfunction is recognized as an early and initiating event in the pathogenesis of coronary artery disease. Gene polymorphisms of endothelial constitutive nitric oxide synthase (ecNOS), angiotensin converting enzyme (ACE) and angiotensin II type 1 receptor (AT1R) have been found to be associated...

journal_title：European review for medical and pharmacological sciences

authors： Akpinar TS,Ozkok A,Kose M,Atas R,Sumnu A,Bakkaloglu OK,Erk O,Kayacan MS,Oflaz H,Akkaya VA,Demirel AS

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To determine alterations of vitamin D and parathyroid hormone levels and their relationship to insulin resistance among a sample of healthy young adult obese Saudis and to identify factors that might predict these alterations. METHODS:Age and gender matched obese young (aged 18-25 years) adult Saudis (N = 7...

journal_title：European review for medical and pharmacological sciences

authors： Al-Sultan AI,Amin TT,Abou-Seif MA,Al Naboli MR

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the effects of oxaliplatin on intestinal floras, inflammation level, apoptosis-related gene expressions and oxidative stress in rats with colorectal cancer. MATERIALS AND METHODS:A total of 30 adult Sprague-Dawley (SD) rats were selected as research objects and were d...

journal_title：European review for medical and pharmacological sciences

authors： Luo H,Liu L,Zhao JJ,Mi XF,Wang QJ,Yu M

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:MicroRNAs play critical roles in regulating gene expression and various cellular processes in human cancer malignant progression. The aim of the present study was to examine the expression pattern of miR-194 in gastric cancer (GC) and its biological role in tumor progression. MATERIALS AND METHODS:Using quan...

journal_title：European review for medical and pharmacological sciences

authors： Bao J,Zou JH,Li CY,Zheng GQ

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:2-aminoethoxydiphenyl borate (2-APB) has been reported to be a useful pharmacological tool in the study of calcium signaling. It is used either as a membrane-permeable inhibitor for inositol 1,4,5-trisphosphate (IP3) receptors or a store-operated calcium (Ca2+) entry (SOCE) inhibitor. The prese...

journal_title：European review for medical and pharmacological sciences

authors： Ng NM,Jiang SP,Zhang W

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To analyze the guiding significance of N-terminal pro-brain natriuretic peptide (NT-proBNP) and procalcitonin (PCT) level in mechanical ventilator used for patients with chronic respiratory failure. PATIENTS AND METHODS:Eighty-two patients with simple chronic respiratory failure who were treated by mechanica...

journal_title：European review for medical and pharmacological sciences

authors： Wang YT,Fu JJ,Li YR,Zang SZ,Yang YR,Zhou CY,Li CF

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To investigate the relationships between blood uric acid (BUA) level and the incidence, progression and deterioration of diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS:A total of fifty patients with T2DM alone whose glycosylated hemoglobin (HbA1c) were under ...

journal_title：European review for medical and pharmacological sciences

authors： Li GX,Jiao XH,Cheng XB

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:In this study, we investigated whether certain types of lipid profiles are major contributors of acute ischemic stroke (AIS). PATIENTS AND METHODS:We screened 13,285 hospitalized patients in two stroke medical centers treated with thrombolysis, thrombectomy, or conventional care for anterior cerebral artery-...

journal_title：European review for medical and pharmacological sciences

authors： Niu L,Jiang SW,Wang Y,Peng Y,Fei AH,Wang HR,Li Y,Zhang JC,Meaney C,Gao CJ,Pan SM

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:This paper aims to evaluate the effects of right ventricular pressure load on left ventricular myocardial mechanics in patients with chronic obstructive pulmonary disease (COPD) by ultrasound speckle tracking imaging. PATIENTS AND METHODS:119 patients with COPD and pulmonary hypertension (PH) were selected f...

journal_title：European review for medical and pharmacological sciences

authors： Xia YJ,Sun HY,Jiang L,Liu B,Wang YY

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Myocardial infarction (MI), which causes irreversible damage and loss of cardiomyocytes, is the most important cause of death in the world. MicroRNA is an important regulator of physiological and pathological activities of cardiovascular system. The aim of this research was to study the effect of microRNA-323...

journal_title：European review for medical and pharmacological sciences

authors： Shi CC,Pan LY,Zhao YQ,Li Q,Li JG

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To investigate the correlations of Homocysteine (Hcy), vascular endothelial growth factor (VEGF), and serum gastrin 17 (G17) with gastric cancer and precancerous lesions. PATIENTS AND METHODS:A total of 56 patients with gastric cancer (gastric cancer group) and 53 patients with precancerous lesions (precance...

journal_title：European review for medical and pharmacological sciences

authors： Zhao WX,Liu ZF,Li XL,Li Z

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of folic acid combined with vitamin B12 on deep vein thrombosis (DVT) in patients with homocysteine cerebral infarction. PATIENTS AND METHODS:90 patients with homocysteine cerebral infarction with DVT that were admitted to our hospital from January to July 2015 were selected as stu...

journal_title：European review for medical and pharmacological sciences

authors： Shu XJ,Li ZF,Chang YW,Liu SY,Wang WH

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To investigate the therapeutic effect of drug therapy with cyclophosphamide and leflunomide on the joint function damage of patients with systemic lupus erythematosus (SLE) and its regulatory effects on expression levels of programmed death receptor 1, Notch signaling pathway genes and interferon-inducible pr...

journal_title：European review for medical and pharmacological sciences

authors： Zhou QS,Hu J,Hu H

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Aberrant activation of (Wingless and mouse homolog Int-1) Wnt/β-catenin signaling pathways closely involved in the occurrence and progression of several types of human malignancies. This research was undertaken to elucidate the important role of (Wingless and mouse homolog Int-1) in lung cancer. PATIENTS AND...

journal_title：European review for medical and pharmacological sciences

authors： Xing Z,Wang HY,Su WY,Liu YF,Wang XX,Zhan P,Lv TF,Song Y

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:MiR-155-5p has various biological cellular functions in diverse pathology, including cardiovascular disease. Nevertheless, the role of miR-155-5p in atherosclerosis is still not well known. PATIENTS AND METHODS:The levels of miR-155-5p and AKT Serine/Threonine Kinase 1 (AKT1) in plasma samples from patients ...

journal_title：European review for medical and pharmacological sciences

authors： Chen L,Zheng SY,Yang CQ,Ma BM,Jiang D

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIM:Inflammatory cells involved in the pathophysiology of asthma express nicotinic receptor. Therefore 1,1 dimethyl(-4-)phenylpiperazinium (DMPP) in two doses were compared to dexamethasone in asthmatic guinea pigs. MATERIALS AND METHODS:Six groups were included; Normal control and five asthmatic (OVA-s...

journal_title：European review for medical and pharmacological sciences

authors： Murad HA,Hasanin AH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the regulatory effect of miR-328 on biological behaviors of hepatocellular carcinoma (HCC) cells, such as invasion and proliferation. PATIENTS AND METHODS:The expressions of miR-328 were detected in 48 pairs of HCC tissue samples and matched adjacent tissues, as well as in 3 kinds of HCC cell ...

journal_title：European review for medical and pharmacological sciences

authors： Liang F,Cui ZJ,Liu JD,Liu KP,Li L,Chen YL

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To explore possible mechanism of ERBB2 gene expression silencing mediating mitogen-activated protein kinase 1/mitogen-activated protein kinase 3 (MAPK1/MAPK3) signaling pathway on proliferation, migration, and invasion of ovarian cancer cells. PATIENTS AND METHODS:A total of 240 cancer specimens were collect...

journal_title：European review for medical and pharmacological sciences

authors： Yu TT,Wang CY,Tong R

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:The aim of our study was to investigate impact of active and passive smoking on total and specific serum IgE levels and on incidence of developing allergic diseases (i.e. asthma, rhinitis) in a group of Croatian adolescents. METHODS:Our study consisted of random sample of one hundred fifty-five (155) volunta...

journal_title：European review for medical and pharmacological sciences

authors： Mlinaric A,Popovic Grle S,Nadalin S,Skurla B,Munivrana H,Milosevic M

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:This study was made to investigate and evaluate the safety and carcinogenicity of nitenpyram (NIT) in rats. MATERIALS AND METHODS:A totally 50 male and 50 female SD rats were treated with NIT at 0, 800, 2400, and 7200 ppm, respectively, for 104 w. The growth, clinical signs, and survival rates, as well as th...

journal_title：European review for medical and pharmacological sciences

authors： Xing LG,Wu YL,Zheng HN,Jia YY,Wu GF,Yang C

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Evidence has shown that psychotherapy is effective for depression, whereas the outcome for suicide risk is unclear. AIM:It was to investigate whether possible pre-treatment predictors of suicide risk (SR) decrease after a brief psychodynamic psychotherapy treatment and at follow-up. PATIENTS AND METHODS:Fo...

journal_title：European review for medical and pharmacological sciences

authors： Angeletti G,D'onofrio M,Lai C,Tambelli R,Aceto P,Girardi P

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the expression of circ_0072309 in patients with ischemic stroke (IS) and in LIFR humanized mice with middle cerebral artery occlusion (MCAO). Further, we explored the underlying mechanism of circ-0072309 in IS. MATERIALS AND METHODS:The content of circ-0072309 in serum of patients with IS (n =...

journal_title：European review for medical and pharmacological sciences

authors： Zhao Y,Li J,Li J,Xu L,Lian W

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Our experience with the treatment of large incisional hernias (IH) was reviewed comparing mesh repair alone vs. mesh repair plus pedicle flaps. MATERIALS AND METHODS:A retrospective study was performed on patients treated between 2001 and 2005 that underwent component separation technique (CST) repair with p...

journal_title：European review for medical and pharmacological sciences

authors： Bogetti P,Boriani F,Gravante G,Milanese A,Ferrando PM,Baglioni E

更新日期：2012-11-01 00:00:00