Hospital readmissions to internal medicine departments: a higher risk for females?

Abstract:

OBJECTIVE:Readmissions to hospital after discharge are considered adverse, serious and costly outcomes. In the last years, two new scores have been proposed to identify patients at high risk of hospital readmission, the HOSPITAL and the Elders Risk Assessment (ERA) indexes. The aim of this study was to evaluate these two scores and the risk of death among internal medicine readmitted patients. PATIENTS AND METHODS:During a 30-month period, we identified 613 readmitted patients out of 13,237 admissions. Age, sex, length-of-hospital stay (LOS), and deaths were retrospectively analyzed. Readmissions with diagnosis coincident with the index hospitalization were classified as avoidable, whilst those with a different diagnosis were defined as non-avoidable. HOSPITAL score for 30-day potentially avoidable readmission and ERA indexes were calculated. RESULTS:Readmitted patients (56.6% women), were aged 79±10.4 years. The incidence of 30-day readmission was 20.4 patients/month. Re-hospitalization could be classified as avoidable in 286 cases (46.7%), and death at the end of follow-up was recorded in 366 (59.7%). HOSPITAL score ≥ 7 and ERA score ≥ 16, both able to identify high risk patients for readmission, were present in 108 (17.6%) and 385 (64.4%) of cases, respectively. Patients with non-avoidable readmissions were older, more frequently female, diabetic, and had higher ERA score than subjects with avoidable readmission. Multivariate logistic regression analysis showed that non-avoidable readmissions were independently associated with female gender (OR 1.410 [95% CI 1.012-1.964], p=0.042), and age (OR 1.025 [95% CI 1.006-1.043], p=0.01), while only age (OR 1.034 [95% CI 1.015-1.054], p<0.001) and ERA score (OR 1.047 [95% CI 1.001-1.095], p=0.047) were independently associated with death at the end of follow-up. CONCLUSIONS:Although re-hospitalization represents frequent phenomenon related to age, non-avoidable readmissions mainly involve female patients. ERA score appears to be an useful practical tool, able to identify high risk patients.

authors

De Giorgi A,Boari B,Tiseo R,López-Soto PJ,Signani F,Gallerani M,Manfredini R,Fabbian F

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

4557-4564

issue

21

eissn

1128-3602

issn

2284-0729

journal_volume

20

pub_type

杂志文章
  • Fluid-fluid levels detected on MRI and mimicking primary aneurismal bone cysts in a case of spinal bone metastasis.

    abstract:INTRODUCTION:Spinal bone metastases may be lytic or sclerotic lesions. Sometimes aneurismal bone cyst (ABC)-like areas (also called "secondary ABC") can be found in giant-cell tumors, osteoblastomas and chondroblastomas but are rare in metastatic tumors. CASE REPORT:A retrospective study on 518 patients surgically tre...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Colangeli S,Rossi G,Ghermandi R,Rimondi E

    更新日期:2014-01-01 00:00:00

  • Pneumatosis intestinalis: a rare cause of lower gastrointestinal bleeding.

    abstract::Pneumatosis intestinalis is an uncommon condition characterized by the presence of gas in the bowel wall. We present the case of a 49-year-old man admitted to our Clinic for his 4 day long haematochezia. Colonoscopy revealed pneumatosis coli as a cause of the lower gastrointestinal bleeding. A wide range of diagnostic...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Burgazli KM,Mericliler M,Greiner H,Göbel T,Erhardt A

    更新日期:2013-09-01 00:00:00

  • LncRNA HCG11 accelerates the progression of hepatocellular carcinoma via miR-26a-5p/ATG12 axis.

    abstract:OBJECTIVE:Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers globally. LncRNA HLA complex group 11 (HCG11) has been reported to play an oncogenic role in multiple cancers. Nevertheless, the role and regulatory mechanism of HCG11 in HCC are not fully addressed. PATIENTS AND METHODS:The abundan...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201912_19771

    authors: Li ML,Zhang Y,Ma LT

    更新日期:2019-12-01 00:00:00

  • MiR-214-3p delays fracture healing in rats with osteoporotic fracture through inhibiting BMP/Smad signaling pathway.

    abstract:OBJECTIVE:The purpose of this study was to explore the mechanism of micro-ribonucleic acid (miR)-214-3p in regulating fracture healing in rats with osteoporosis. MATERIALS AND METHODS:A total of 30 female Sprague-Dawley rats were selected and randomly divided into 3 groups, including group A [phosphate-buffered saline...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201901_16854

    authors: Zhou LG,Shi P,Sun YJ,Liu HZ,Ni JQ,Wang X

    更新日期:2019-01-01 00:00:00

  • Neuropathic pain following spinal cord injury: what we know about mechanisms, assessment and management.

    abstract:BACKGROUND:In biology, it is easy to understand how a damaged functional system may generate wrong signals, but why this should happen when the system is disconnected is less clear. For this reason, among other pain syndromes, neuropathic pain (NP) following spinal cord injury (SCI) leaves most questions unanswered. A...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: D'Angelo R,Morreale A,Donadio V,Boriani S,Maraldi N,Plazzi G,Liguori R

    更新日期:2013-12-01 00:00:00

  • A study on the polymicrobial etiology of root canal infections in anterior non-vital teeth in a government hospital in Kolkata, India.

    abstract::A total of 52 patients having non-vital anterior teeth who attended at the Department of Conservative Dentistry of a Government Dental College of the city of Kolkata, India where studied for isolation of different microflora in the root canals of the non-vital teeth. 41 (78.8%) out of 52 cases studied showed the prese...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Chakraborty P,Chattopadhyay UK

    更新日期:2005-03-01 00:00:00

  • Influence of sepsis on higher daily dose of amikacin pharmacokinetics in critically ill patients.

    abstract:BACKGROUND AND OBJECTIVES:Severe sepsis is a major problem as cause of high rates morbidity and mortality in intensive care units (ICU). Aminoglycosides are an important group of antimicrobials used for severe sepsis. However, aminoglycoside pharmacokinetics in ICU patients may be altered during sepsis, which can affec...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 临床试验,杂志文章

    doi:

    authors: Mahmoudi L,Mohammadpour AH,Ahmadi A,Niknam R,Mojtahedzadeh M

    更新日期:2013-02-01 00:00:00

  • Expression of miR-182 in patients with fracture of tibial plateau and its regulative effects on the fracture healing.

    abstract:OBJECTIVE:To investigate the expression of miR-182 in patients with fracture of tibial plateau (FTP) and its effects on osteoblasts and fracture healing. PATIENTS AND METHODS:The patients with fracture of tibial plateau treated in our hospital and healthy subjects who received physical examination from January 2017 to...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202101_24343

    authors: Yan ZW,Du P,Zhang W,Sun WC,Jia L,Jiang M,Liu Y,Guo HL

    更新日期:2021-01-01 00:00:00

  • MicroRNA-23a induces apoptosis of hepatocarcinoma cell line MHCC97H via down-regulating KIAP: a mechanism study.

    abstract:OBJECTIVE:Hepatocarcinoma is a great threat to global health. MicroRNA-23a was suggested to regulate growth and apoptosis in certain cell lines. Our study was focused on growth, proliferation, and apoptosis of hepatocarcinoma cell line MHCC97H under the influence of microRNA-23a, and explored the mechanism of pro-apopt...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201809_15918

    authors: Ji DG,Jiang CW,Luo X,Liu Z,Huang WJ,Zhang XH,Yu TH,Zhang LR

    更新日期:2018-09-01 00:00:00

  • 2-Aminoethoxydiphenyl borate reduces degranulation and release of cytokines in a rat mast cell line.

    abstract:BACKGROUND AND OBJECTIVE:2-aminoethoxydiphenyl borate (2-APB) has been reported to be a useful pharmacological tool in the study of calcium signaling. It is used either as a membrane-permeable inhibitor for inositol 1,4,5-trisphosphate (IP3) receptors or a store-operated calcium (Ca2+) entry (SOCE) inhibitor. The prese...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Ng NM,Jiang SP,Zhang W

    更新日期:2012-08-01 00:00:00

  • Computerized dynamic pupillometry indices mirrors the heart rate variability parameters.

    abstract:OBJECTIVE:Dynamic pupillometry (DP) is a simple, non-invasive computerized assessment of pupillary light response which provides data concerning both branches of the autonomous nervous system (ANS). Heart rate variability (HRV) analysis assess cardiac health and the ANS modulation on the heart. In this study, we aimed ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Okutucu S,Civelekler M,Aparci M,Sabanoglu C,Dikmetas O,Aksoy H,Yetis Sayin B,Oto A

    更新日期:2016-05-01 00:00:00

  • MicroRNA-138 inhibits proliferation and induces apoptosis of laryngeal carcinoma via targeting MAPK6.

    abstract:OBJECTIVE:To explore whether microRNA-138 could regulate the incidence and progression of laryngeal carcinoma through modulating proliferation and apoptosis of laryngeal carcinoma cells via MAPK6. PATIENTS AND METHODS:MicroRNA-138 expression in laryngeal carcinoma tissues and paracancerous tissues were detected by qRT...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201809_15820

    authors: Zhou YH,Huang YY,Ma M

    更新日期:2018-09-01 00:00:00

  • Influence of dexmedetomidine to cognitive function during recovery period for children with general anesthesia.

    abstract:OBJECTIVE:We studied the influence of Dexmedetomidine on cognitive function in children during the recovery period of general anesthesia. PATIENTS AND METHODS:Ninety-three children who underwent general anesthesia were selected and randomly divided into (1) the control group, (2) the dexmedetomidine group, and (3) the...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Jia ZM,Hao HN,Huang ML,Ma DF,Jia XL,Ma B

    更新日期:2017-03-01 00:00:00

  • Influence of lncRNA ANRIL on neuronal apoptosis in rats with cerebral infarction by regulating the NF-κB signaling pathway.

    abstract:OBJECTIVE:The aim of this study was to evaluate the influence of long non-coding ribonucleic acid (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) on neuronal apoptosis in rats with cerebral infarction (CI), and to further explore the underlying mechanism of lncRNA ANRIL in the occurrence and development of ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201911_19577

    authors: Zhao JH,Wang B,Wang XH,Wang JR,Xu CW

    更新日期:2019-11-01 00:00:00

  • An update on the status of COVID-19: a comprehensive review.

    abstract::The last two decades have witnessed two large-scale pandemics caused by coronaviruses, including severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS). At the end of 2019, another novel coronavirus, designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), hit Wuhan...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:10.26355/eurrev_202004_21046

    authors: Zhao N,Zhou ZL,Wu L,Zhang XD,Han SB,Bao HJ,Shu Y,Shu XG

    更新日期:2020-04-01 00:00:00

  • CircRNA_100395 protects breast carcinoma deterioration by targeting MAPK6.

    abstract:OBJECTIVE:This study aims to uncover the differential expression of circRNA_100395 in breast carcinoma specimens, and its regulatory effect on cancer cell phenotypes. The role of circRNA_100395 in affecting breast carcinoma progression and the molecular mechanism are explored as well. PATIENTS AND METHODS:CircRNA_1003...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202012_24012

    authors: Yu XP,Liu CG,Qiu F,Xu YQ,Xing F,Yin JQ,Han SJ,Yu H,Han Y,Jing X,He GJ

    更新日期:2020-12-01 00:00:00

  • Bioinformatics analysis of gene expression profiles in the rat cerebral cortex following traumatic brain injury.

    abstract:BACKGROUND:Traumatic brain injury (TBI) is a serious neurodisorder commonly caused by sports related events or violence. It is the leading cause of disability in people under 40. AIM:In order to elucidate the molecular mechanism of the secondary injury after TBI. MATERIALS AND METHODS:In this study, we downloaded gen...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Ou S,Liu GD,Zhou LS,Xia X,Bai SR,Li J,Cui J,Cheng JM,Li YM,Zhang XY,Gu JW

    更新日期:2014-01-01 00:00:00

  • Ugly duckling or Nosferatu? Cardiac injury in endurance sport - screening recommendations.

    abstract::In the beginning sporting activity may be exhausting, but over time, physical activity turns out to have beneficial effects to the body and even extended cycling or running is an emotional and healthy enrichment in life. On the other hand, spectacular sudden deaths during marathon, football and, just recently, in the ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Leischik R,Dworrak B

    更新日期:2014-01-01 00:00:00

  • IL-6 stimulates lncRNA ZEB2-AS1 to aggravate the progression of non-small cell lung cancer through activating STAT1.

    abstract:OBJECTIVE:To illustrate the role of interleukin 6 (IL-6) in the progression of non-small cell lung cancer (NSCLC) via activating STAT1. PATIENTS AND METHODS:The level of IL-6 mRNA in 48 paired NSCLC tissues and matched normal ones was determined by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). Kaplan-Mei...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202004_20837

    authors: Chen T,Li J,Zhou MH,Xu LJ,Pan TC

    更新日期:2020-04-01 00:00:00

  • Effect of single nucleotide polymorphisms on CDK4 and Zn supplementation in children with growth hormone deficiency.

    abstract:OBJECTIVE:Precision medicine is a personalized disease prevention and treatment program combining modern genetic technology, molecular imaging techniques, and biological information with patients' living environment and clinical data, for accurate classification and diagnosis of diseases. CASE REPORT:Our study present...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Liu Y,Zhang ZX

    更新日期:2016-10-01 00:00:00

  • Proanthocyanidins affects the neurotoxicity of Aβ25-35 on C57/bl6 mice.

    abstract:OBJECTIVE:To investigate the influence of procyanidins on the impairment of memory. MATERIALS AND METHODS:Thirty male C57bl/6 mice were divided into five groups: low, middle, and high concentration, model, and control groups. Intracerebroventricular injection of β-amyloid25-35 in C57bl/6 mice caused an impairment of l...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: He Q,Yang SY,Wang W,Wu ZJ,Ma HL,Lu Y

    更新日期:2016-01-01 00:00:00

  • Histamine H3 receptor antagonist Clobenpropit protects propofol-induced apoptosis of hippocampal neurons through PI3K/AKT pathway.

    abstract:OBJECTIVE:The aim of the study was to explore whether histamine H3 receptor antagonist Clobenpropit could protect propofol-induced neurotoxicity in hippocampal neurons. MATERIALS AND METHODS:Hippocampal neurons were extracted from neonatal rats and induced with propofol. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201811_16430

    authors: He W,Yuan QH,Zhou Q

    更新日期:2018-11-01 00:00:00

  • Ischemic preconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PERK pathway.

    abstract:OBJECTIVE:The purpose of this study was to explore the effects of cerebral ischemic preconditioning which can decrease brain ischemia/reperfusion (I/R) injury by inhibiting endoplasmic reticulum (ER) stress-induced apoptosis. MATERIALS AND METHODS:The focal cerebral ischemia rat was selected as the experimental model....

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201712_14020

    authors: Hu YQ,Chen W,Yan MH,Lai JJ,Tang N,Wu L

    更新日期:2017-12-01 00:00:00

  • Bioinformatics analysis of common differential genes of coronary artery disease and ischemic cardiomyopathy.

    abstract:OBJECTIVE:This paper aims at screening the common differential genes of coronary atherosclerotic heart disease (CAD) and ischemic cardiomyopathy (ICM), and to conduct pathway analysis and protein-protein interaction (PPI) network analysis for the differential genes. MATERIALS AND METHODS:The CAD and ICM datasets were ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201806_15182

    authors: Li GM,Zhang CL,Rui RP,Sun B,Guo W

    更新日期:2018-06-01 00:00:00

  • Prophylactic misoprostol for the prevention of postpartum hemorrhage: a randomized controlled trial.

    abstract:OBJECTIVE:Postpartum hemorrhage (PPH) is one of the major preventable causes of maternal death in developing countries. Although the non-parenteral use of misoprostol is a big advantage especially in home births, its benefits in prevention of PPH is still debating. We aimed to assess the effect and side-effects of prop...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Uncu Y,Karahasan M,Uyaniklar Ö,Uncu G

    更新日期:2015-01-01 00:00:00

  • MiR-204 reduces apoptosis in rats with myocardial infarction by targeting SIRT1/p53 signaling pathway.

    abstract:OBJECTIVE:The aim of this study was to investigate the influence of micro ribonucleic acid (miR)-204 on rats with myocardial infarction by targeting the silent information regulator 1 (SIRT1)/p53 signaling pathway. MATERIALS AND METHODS:A total of 36 Sprague-Dawley rats were randomly divided into three groups, includi...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202012_24023

    authors: Wang LZ,Xi JN,Liu TJ,Zhang ZY,Zhang P

    更新日期:2020-12-01 00:00:00

  • LncRNA SNHG1 overexpression regulates the proliferation of acute myeloid leukemia cells through miR-488-5p/NUP205 axis.

    abstract:OBJECTIVE:To elucidate the function of long non-coding RNA (lncRNA) SNHG1 in acute myeloid leukemia (AML) and to explore its biological mechanism. PATIENTS AND METHODS:Expression levels of lncRNA SNHG1 and miR-488-5p in AML cell lines pAML and THP-1 were determined by quantitative Real Time-Polymerase Chain Reaction (...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_201907_18334

    authors: Bao XL,Zhang L,Song WP

    更新日期:2019-07-01 00:00:00

  • Is the pepper spray a triggering factor in myocardial infarction? A case report.

    abstract::Forty-year-old man was admitted to emergency department with complains of chest pain and dispnea after exposure the pepper gas that sprayed to environment during a social event. Physical examination and electrocardiogram was revealed acute myocardial infarction. ...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:

    authors: Cil H,Atilgan ZA,Islamoğlu Y,Tekbaş EO,Dostbil Z

    更新日期:2012-03-01 00:00:00

  • Mechanical thrombectomy with Solitaire stent for acute internal carotid artery occlusion without atherosclerotic stenosis: dissection or cardiogenic thromboembolism.

    abstract:BACKGROUND:In acute ischemic stroke patients, internal carotid artery occlusion with middle cerebral artery (ICA/MCA) occlusion in succession predicts a poor outcome after systemic thrombolysis. It is not known whether this occlusion subtype of the anterior circulation is due to dissections or cardiogenic thromboemboli...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Ma YD,Wang J,Du ZH,Cao XY,Zhou DB,Li BM

    更新日期:2014-01-01 00:00:00

  • Clinical characteristics and outcomes of 2019-nCoV-infected patients admitted at different time periods.

    abstract:OBJECTIVE:The outbreak of the 2019 Novel Coronavirus Disease (COVID-19) is seriously threatening the health of people all over China and the world. This study aims to investigate the clinical characteristics and outcomes of COVID-19 patients admitted at different time periods. PATIENTS AND METHODS:A total of 132 disch...

    journal_title:European review for medical and pharmacological sciences

    pub_type: 杂志文章

    doi:10.26355/eurrev_202007_22287

    authors: Liu WR,Zuo GJ,Qin Y

    更新日期:2020-07-01 00:00:00