Abstract：
OBJECTIVES:Functional somatic syndromes are common and disabling conditions that all include chronic pain, and which may be related to central nervous system sensitisation. Here, we address the concept of central sensitisation as a physiological basis for the functional somatic syndromes. METHODS:A narrative review of the current literature on central sensitisation and physiological studies in the functional somatic syndromes. RESULTS:Central sensitisation may be a common neurophysiological process that is able to explain non-painful as well as painful symptoms in these disorders. Furthermore, central sensitisation may represent an endophenotypic vulnerability to the development of these syndromes that potentially explains why they cluster together. CONCLUSIONS:Further research is needed to verify these findings, including prospective studies and the standardisation of combined methods of investigation in the study of central sensitisation in functional somatic syndromes. In turn, this may lead to new explanatory mechanisms and treatments being evaluated. Our conclusions add to the debate over the nomenclature of these syndromes but importantly also provide an explanation for our patients.
journal_name
J Psychosom Resjournal_title
Journal of psychosomatic researchauthors
Bourke JH,Langford RM,White PDdoi
10.1016/j.jpsychores.2015.01.003subject
Has Abstractpub_date
2015-03-01 00:00:00pages
228-36issue
3eissn
0022-3999issn
1879-1360pii
S0022-3999(15)00005-7journal_volume
78pub_type
杂志文章,评审abstract：OBJECTIVE:Functional memory disorder (FMD) is an acquired nonorganic condition characterized by significant deficits of memory and concentration that occur in daily living and are thought to be caused by psychosocial burden and distress. FMD is an important differential diagnosis to organic mild cognitive impairment. A...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2009.04.005
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:Chronic fatigue syndrome (CFS) describes a condition that is primarily characterized by fatigue and flu-like symptoms that are not alleviated by rest. This study investigated the relationship among metacognitions, negative emotions, and symptom severity in CFS. METHODS:A total of 96 patients who had received...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2010.09.016
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:In this study, we investigated whether psychological factors were associated with subsequent acute exacerbation of tension-type headache (TTH) in a prospective and ecologically valid manner with computerized ecological momentary assessment. METHODS:Eighteen women and five men with TTH wore watch-type compute...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2015.06.008
更新日期：2015-09-01 00:00:00
abstract：:In this prospective study, 137 patients with chronic fatigue syndrome were followed-up at a 1-year interval to determine factors relating to outcomes. Nearly two thirds reported an improvement on direct ratings of change. In analyses with fatigue and functional impairment at follow-up as the criteria, and controlling ...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/s0022-3999(97)00111-6
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:To determine the relative contribution of demographic variables, objective testing and psychological factors in explaining the variance in dizziness severity and handicap. METHODS:One-hundred and eighty-five consecutive patients on the waiting list to attend a diagnostic appointment in a tertiary neuro-otolo...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2020.109969
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To explore the association between depressive symptom history and cancer incidence. METHODS:Affective/emotional depressive symptoms were assessed using the General Health Questionnaire (GHQ-30) depression sub-scale across phase 1 (1985-1988), phase 2 (1989-1990), and phase 3 (1991-1994) of the Whitehall II p...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2015.07.011
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:Twenty-five years ago, this journal published two articles reporting the development and initial validation of the 20-Item Toronto Alexithymia Scale (TAS-20). Since then the literature on alexithymia has burgeoned with the vast majority of this research using the TAS-20, including multiple language translatio...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章,评审
doi：10.1016/j.jpsychores.2020.109940
更新日期：2020-01-23 00:00:00
abstract：BACKGROUND:Heterozygous familial hypercholesterolemia (FH) is a common genetic disease predisposing affected individuals to a high risk of cardiovascular disease. Yet, considerable uncertainty exists regarding its impact on psychosocial wellbeing. OBJECTIVES:We performed a systematic review and meta-analysis of the as...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章,meta分析
doi：10.1016/j.jpsychores.2018.03.170
更新日期：2018-06-01 00:00:00
abstract：:Nausea, unlike emesis, is a subjective experience that is difficult to describe to others, be they clinicians or researchers. Previous research has been limited to examining the frequency, severity, and duration of nausea. The goal of this study was to design a questionnaire that would allow for the evaluation of the ...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(95)00638-9
更新日期：1996-05-01 00:00:00
abstract：:A prospective 4-year follow-up study was conducted to compare the psychosocial adjustment process and survival rate of 59 stoma patients with 64 bowel-resected nonstoma patients. Adjustment was assessed at 4 months. 1 year, and 4 years after surgery by the Psychosocial Adjustment to Illness Scale, a self-report questi...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/s0022-3999(96)00288-7
更新日期：1997-03-01 00:00:00
abstract：:The effect of exercise training on quality of life and exercise capacity was studied in 67 patients with mild to moderate chronic heart failure (CHF; age: 65.6+/-8.3 years; left ventricular ejection fraction: 26.5+/-9.6%). Patients were randomly allocated to either a training group or to a control group. After interve...
journal_title：Journal of psychosomatic research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0022-3999(97)00309-7
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVE:Caregivers of patients with cancer experience a variety of psychological distress. This study aimed to investigate the mental health status and depressive disorder predictors in caregivers of patients with head and neck cancer (HNC) over a six-month follow-up. METHODS:We recruited the participants for this s...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2017.07.002
更新日期：2017-09-01 00:00:00
abstract：:A decreased sensitivity to painful stimuli and high scores for alexithymia and depression have been observed in patients with eating disorders. We investigated the relationship between these factors in 22 patients with anorexia nervosa, 18 patients with bulimia nervosa, and 32 healthy subjects. Alexithymia was assesse...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(96)00088-8
更新日期：1996-07-01 00:00:00
abstract：:Disturbances of sleep are a hallmark of seasonal affective disorders (SAD), as they are of other mood disorders. Fall/winter SAD patients most often report hypersomnia. Among responses of 293 SAD patients on a symptom questionnaire, complaints of winter hypersomnia (80%) greatly exceeded insomnia (10%), hypersomnia pl...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(94)90037-x
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVE:Living with food allergy is a unique and potentially life-threatening stressor that requires constant vigilance to food-related stimuli, but little is known about whether adolescents with food allergies are at increased risk for psychopathology-concurrently and over time. METHODS:Data came from the prospecti...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2014.10.005
更新日期：2014-12-01 00:00:00
abstract：:The predictive validity of subjects' self-reports of the severity of four groups of symptoms associated with the premenstrual syndrome (PMS) was assessed by canonical correlation of retrospective self-reports of usual symptom severities with prospectively obtained symptom severity scores from the next two cycles. Pros...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/0022-3999(87)90075-4
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:Investigate the association of dispositional optimism with chronic kidney disease (CKD) and rapid kidney function decline (RKFD) and determine if there is modification by age, sex, and educational attainment among African Americans. METHODS:Optimism was measured using the 6-item Life Orientation Test-Revised...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2020.110267
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVE:To administer and validate the Hospital Anxiety and Depression Scale (HADS) via the Internet to a sample of persons with tinnitus. METHOD:The HADS was converted into a Web page and administered via the Internet to a sample of 157 persons with tinnitus who were recruited for participation in a treatment trial...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/s0022-3999(02)00575-5
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:The aim of this preliminary study was to characterize the levels of plasma adrenocorticotropic hormone (ACTH) and cortisol in adult patients with Asperger syndrome (AS). METHODS:Twenty medication-free individuals with high-functioning AS were recruited from a clinic specialized in autism spectrum disorders. ...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2004.12.004
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:Multiple physical symptoms not attributable to known organic disease are common in all medical fields and associated with major personal and social consequences. This study investigated multiple physical symptoms according to the construct of bodily distress syndrome (BDS) and associated individual characteri...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2020.109941
更新日期：2020-01-28 00:00:00
abstract：BACKGROUND:Sleep disorders are very common in patients with chronic kidney disease and they may not always subside after kidney transplantation. AIM AND METHODS:The aim of this cross-sectional study was to evaluate the self-reported quality of sleep, insomnia problems in particular, and examine the factors that distur...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2016.12.013
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:Dispositional optimism has been associated with a lower risk of cardiovascular mortality, but the underlying mechanisms are still largely unknown. We therefore studied whether dispositional optimism was associated with healthy lifestyle and dietary habits. METHODS:In 773 (87.1%) of 887 Dutch elderly communit...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2007.07.014
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:Arterial stiffness is identified as a causative factor for hypertension. The purpose of this study was to explore the relationship between psychological stress and arterial stiffness in Korean Americans. METHODS:A convenience sample of 102 Korean Americans (aged 21-60 years, 60% women) was recruited from Nor...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2012.04.008
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:Detailed evidence for the construct validity of stress questionnaires has been repeatedly demanded. This study aimed to investigate the construct validity of the Perceived Stress Questionnaire (PSQ) in the context of a transactional view of stress. METHODS:The examination was based on the PSQ and on standard...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2007.02.010
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:This review aimed to examine evidence for the role of hormonal changes in the onset and course of depressive symptomatology and to assess the possible future role of hormonal therapies in the treatment of depression. METHODS:A Medline and PsycINFO search of the literature published between 1965 and 2006 was ...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章,评审
doi：10.1016/j.jpsychores.2006.12.019
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:To determine whether presence of ikigai as a positive psychological factor is associated with decreased risks for all-cause and cause-specific mortality among middle-aged and elderly Japanese men and women. METHODS:From 1988 to 1990, a total of 30,155 men and 43,117 women aged 40 to 79 years completed a life...
journal_title：Journal of psychosomatic research
pub_type： 临床试验,杂志文章
doi：10.1016/j.jpsychores.2008.10.018
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVES:Body dysmorphic disorder (BDD) is characterized by an excessive preoccupation with an imagined or minor appearance flaw. Many aspects of BDD remain unknown, such as rates of treatment utilization, types of treatment sought, and barriers to treatment. The present study sought to examine rates and patterns of ...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2010.10.002
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:Current evidence regarding the association between psychopathology and subclinical atherosclerosis show inconsistent results. The present study examined whether subclinical atherosclerosis was more prevalent in a large cohort of persons with depressive or anxiety disorders as compared to non-depressed and non...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2010.01.005
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:Mind-body therapies (MBT) are used by 16.6% of adults in the United States. Little is known about the patterns of and reasons for use of MBT by adults with common medical conditions. METHODS:We analyzed data on MBT use from the 2002 National Health Interview Survey Alternative Medicine Supplement (n=31,044)....
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2008.12.003
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVE:To compare resilience in women with SLE and healthy women and determine whether sociodemographic factors and depressive symptoms were associated with resilience in patients with SLE. METHODS:This was a cross-sectional study. Participants were 123 women with SLE according to the ACR criteria and 132 age-match...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/j.jpsychores.2019.05.002
更新日期：2019-07-01 00:00:00
