[In vitro susceptibility of Cryptococcus strains to 5 antifungal drugs].

Abstract:

:A comparative study of the "in vitro" susceptibility of 24 Cryptococcus strains to 5 antifungal drugs (amphotericin B, 5 fluorocytosine, miconazole, itraconazole and ketoconazole), was carried out. These strains were grouped according to species, varieties and isolation's origins. The minimum inhibitory concentration (M.I.C.) was determined by the agar dilution technique in yeast nitrogen base agar with dextrose. The mean geometrical of the M.I.C. values of each group was compared with the others. The results obtained were homogeneous with the only exception of the "non neoformans" strains, in which, higher M.I.C. to 5 fluorocytosine values were detected.

authors

Bava AJ,Negroni R

doi

10.1590/s0036-46651989000500009

subject

Has Abstract

pub_date

1989-09-01 00:00:00

pages

346-50

issue

5

eissn

0036-4665

issn

1678-9946

journal_volume

31

pub_type

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