Resolution of cutaneous leishmaniasis after acute eczema due to intralesional meglumine antimoniate.

Abstract:

:We report a case of a 42 year-old female, who came to a leishmaniasis reference center in Rio de Janeiro, Brazil, presenting a cutaneous leishmaniasis lesion in the right forearm. Treatment with low-dose intramuscular meglumine antimoniate (MA) (5 mg Sb5+/kg/day) was initiated, with improvement after 28 days, although with the development of generalized eczema. After 87 days, the lesion worsened. Patient refused treatment with amphotericin B. MA was then infiltrated in the lesion, in two sessions, resulting in local eczema, with bullae formation; however, twenty days after, both the ulcer and eczema receded. Intralesional administration of MA should be used carefully when previous cutaneous hypersensitivity is detected.

authors

Ferreira e Vasconcellos Ede C,Pimentel MI,Valete-Rosalino CM,Madeira Mde F,Schubach Ade O

doi

10.1590/s0036-46652014000400016

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

361-2

issue

4

eissn

0036-4665

issn

1678-9946

pii

S0036-46652014000400361

journal_volume

56

pub_type

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