Capnocytophaga sputigena bloodstream infection in hematopoietic stem cell transplantations: two cases report and review of the literature.

Abstract:

:Capnocytophaga is a group of facultative anaerobic gram-negative bacteria present in the oral cavity of humans, dogs and cats, as part of their normal oral flora. Here, we described two cases of bloodstream infections (BSI) caused by Capnocytophaga in neutropenic autologous hematopoietic stem cell transplantation (auto-HSCT) patients with mucositis (Grade I and Grade III) identified by Maldi-Tof. They were successfully treated with β-lactam (meropenem and piperacillin-tazobactam). The species C. sputigena was confirmed by 16S rRNA gene sequencing in one patient. The review of literature showed that C. ochraceae was the most frequent species causing BSI in auto-HSCT patients and that the patients usually presented mucositis and were neutropenic at the onset of the infection.

authors

Mendes FR,Bruniera FR,Schmidt J,Cury AP,Rizeck C,Higashino H,Oliveira FN,Rossi F,Rocha V,Costa SF

doi

10.1590/s1678-9946202062048

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

e48

eissn

0036-4665

issn

1678-9946

pii

S0036-46652020000100512

journal_volume

62

pub_type

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