Hepatorenal syndrome: aetiology, diagnosis, and treatment.

Abstract:

:Acute renal impairment is common in patients with chronic liver disease, occurring in approximately 19% of hospitalised patients with cirrhosis. A variety of types of renal impairment are recognised. The most important of these is the hepatorenal syndrome, a functional renal impairment due to circulatory and neurohormonal abnormalities that underpin cirrhosis. It is one of the most severe complications of cirrhosis with survival often measured in weeks to months. A variety of treatment options exist with early diagnosis and appropriate treatment providing the best hope for cure. This paper provides a comprehensive and up-to-date review of hepatorenal syndrome and lays out the topic according to the following sections: pathophysiology, historical developments, diagnostic criteria and limitations, epidemiology, precipitating factors, predictors, clinical and laboratory findings, prognosis, treatment options, prophylaxis, and conclusion.

authors

Low G,Alexander GJ,Lomas DJ

doi

10.1155/2015/207012

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

207012

eissn

1687-6121

issn

1687-630X

journal_volume

2015

pub_type

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