Abstract：
:The safety and efficacy of current ACIP guidelines for the prevention and control of influenza in nursing home populations are uncertain. An outbreak of influenza A/Sichuan (H3N2) in a teaching nursing home during 1988 gave us the opportunity to evaluate the effectiveness of an influenza vaccination and amantadine prophylaxis protocol. Over 13 days, 12 of 60 residents developed influenza. Prior influenza vaccination had been given to 94% of the residents. Protection from infection occurred in those tested who had antibody levels greater than or equal to 1:16 to the A/Leningrad (H3N2) antigen contained in the standard 1987-88 trivalent vaccine. However, five of 17 vaccinated residents who were tested had antibody levels less than or equal to 1:16 at the start of the outbreak. Amantadine (less than or equal to 100 mg/day) was given to all but one resident starting on the third day of the outbreak, and to employees starting on the sixth day of the outbreaks. Seven residents developed illness after the start of amantadine, although amantadine appeared to ameliorate their symptoms. Although amantadine was generally well tolerated by residents, employees receiving amantadine identified a high incidence of side effects and only 44% of employees took at least 70% of the prescribed amantadine. In our opinion, early detection and protocol-directed intervention probably abated a more severe influenza outbreak. Therefore we support existing recommendations that formal nursing home policies be established to ensure that residents and employees receive annual influenza vaccine and that chemoprophylaxis be used when outbreaks of influenza A are suspected.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Peters NL,Oboler S,Hair C,Laxson L,Kost J,Meiklejohn Gdoi
10.1111/j.1532-5415.1989.tb06809.xsubject
Has Abstractpub_date
1989-03-01 00:00:00pages
210-8issue
3eissn
0002-8614issn
1532-5415journal_volume
37pub_type
杂志文章abstract：BACKGROUND/OBJECTIVES:Delirium is common in older adults, especially following hospitalization. Because low vitamin D levels may be associated with increased delirium risk, we aimed to determine the prognostic value of blood vitamin D levels, extending our previous genetic analyses of this relationship. DESIGN:Prospec...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16853
更新日期：2020-10-05 00:00:00
abstract：:Salivary gland function is generally well-preserved in healthy older persons. Similar results are observed in the laboratory rat. Older people are, however, more likely to experience salivary disorders due to disease or its treatment. For many patients with remaining salivary gland parenchymal tissue, improved functio...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1989.tb02644.x
更新日期：1989-05-01 00:00:00
abstract：:Research indicates that lower extremity muscle weakness in the elderly is consistently related to impaired mobility and fall risk. Reversible components of the muscle weakness of aging include underuse syndromes and undernutrition, both of which are prevalent in nursing home populations. The Boston FICSIT study is a n...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1532-5415.1993.tb06714.x
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:Guidelines recommend avoidance of several psychoactive medications such as hypnotics in older adults due to their adverse effects. Older patients on hemodialysis may be particularly vulnerable to complications related to use of these agents, but only limited data are available about the risks in this populat...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15740
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVES:To determine whether older adults with mild cognitive impairment (MCI), a condition not previously explored as a risk factor, have more hospitalizations and 30-day readmissions than those with normal cognition. DESIGN:Post hoc analysis of prospectively gathered data on incident hospitalization and readmissi...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
doi：10.1111/jgs.13593
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVES:To investigate whether anticholinergic burden scores from nine published anticholinergic scales are associated with adverse health outcomes, including hospital admissions, hospitalizations for falls, hospital length of stay (LOS), and more visits to general practitioners (GPs). DESIGN:Pharmacoepidemiologica...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13206
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To compare cognitive performance among Japanese and American persons, aged 68 years and older, using two nationally representative studies and to examine whether differences can be explained by differences in the distribution of risk factors or in their association with cognitive performance. DESIGN:National...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16163
更新日期：2020-02-01 00:00:00
abstract：:To help determine whether or not the elderly are at unusually high risk for hospital-related complications, a study was made of consecutive admissions involving 48 patients less than 65 years old (mean 50.3 years) and 174 patients more than 65 years old (mean 73.1 years). They were prospectively followed during their ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1982.tb02837.x
更新日期：1982-06-01 00:00:00
abstract：OBJECTIVES:To determine the effect of body mass index (BMI) at old age and at age 50 on short-term survival among persons age 65 and older. DESIGN:Cross-sectional, using the 4,791 respondents to the community interview of the 1994 National Long Term Care Survey (NLTCS). SETTING:United States of America. PARTICIPANTS...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.49259.x
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVE:To determine how physical activity at various ages over the life course is associated with cognitive impairment in late life. DESIGN:Cross-sectional study. SETTING:Four U.S. sites. PARTICIPANTS:Nine thousand three hundred forty-four women aged 65 and older (mean 71.6) who self-reported teenage, age 30, age...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1532-5415.2010.02903.x
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Home-delivered meal programs serve a predominantly homebound older adult population, characterized by multiple chronic conditions, functional limitations, and a variety of complex care needs, both medical and social. DESIGN:A pilot study was designed to test the feasibility of leveraging routine meal-delive...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16013
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVES:To determine the association between psychoactive medications and crash risk in drivers aged 60 and older. DESIGN:Retrospective population-based case-crossover study. SETTING:A database study that linked the Western Australian Hospital Morbidity Data System and the Pharmaceutical Benefits Scheme. PARTICIP...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03561.x
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVES:To determine whether providing physical therapy (PT) services in the emergency department (ED) improves outcomes for older adults who fall. DESIGN:We used Medicare claims data to examine differences in recurrent fall-related ED revisit rates of older adults who presented to the ED for a ground-level fall an...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15469
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVES:Family caregiving is an integral part of the care system for persons with dementing disorders, such as Alzheimer's disease. This study tested role-training intervention as a way to help family caregivers appreciate and assume a more clinical belief set about caregiving and thereby ameliorate the adverse outc...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1046/j.1532-5415.2001.49090.x
更新日期：2001-04-01 00:00:00
abstract：OBJECTIVES:To examine differences in a proxy measure of muscle quality across the adult life span and explore potential mechanisms of muscle quality change through identification of cross-sectional correlates of muscle quality. DESIGN:Cross-sectional study. SETTING:Baltimore Longitudinal Study of Aging. PARTICIPANTS...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12653
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVES:To evaluate the relationship between frailty and delirium. DESIGN:Systematic review and meta-analysis. SETTING:MEDLINE, EMBASE, PubMed, Scopus, Web of Science, and Google Scholar databases were searched for articles on frailty and delirium published on or before October 31, 2017. PARTICIPANTS:Individuals ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,meta分析
doi：10.1111/jgs.15503
更新日期：2018-10-01 00:00:00
abstract：:Arguments have been made that the culture of nursing homes (NHs) must change to improve the quality of care, and two initiatives have been designed to accomplish this goal. One initiative is to provide resident outcome information (quality indicators) to NH management and consumers via public reporting systems. This i...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52372.x
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVES:To compare the cognitive profile of a population representative sample with orthostatic hypotension (OH) with the profile of a sample without. DESIGN:Cross-sectional analysis of a prospective nationally representative population study. SETTING:The Irish Longitudinal Study on Ageing (TILDA). PARTICIPANTS:T...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12592
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:Factors specifically affecting compliance with continuous positive airway pressure (CPAP) in older patients with obstructive sleep apnea (OSA) have not been described. The purpose of this study is to determine which factors are associated with compliance and noncompliance in older patients, a growing segment...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1046/j.1532-5415.2001.49238.x
更新日期：2001-09-01 00:00:00
abstract：BACKGROUND:Coffee and tea are two of the most widely consumed beverages worldwide and have been associated with reduced risk of mortality in some studies. However, it is unknown whether consumption of these beverages is associated with survival to an advanced age. OBJECTIVE:To examine associations of coffee and tea co...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16467
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVES:The Centers for Medicare & Medicaid Services (CMS) Nursing Home Quality Initiative aims to improve quality through performance measurement. We describe quality improvement (QI) changes that skilled nursing facilities (SNFs) reported making in response to CMS performance measurements and whether reported QI c...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16466
更新日期：2020-09-01 00:00:00
abstract：:Frailty is a common and central problem of old age. Recent research has defined frailty as an accumulation of deficits or as a distinct clinical syndrome involving specific comorbid physical disorders and functional impairment, but the psychological aspects of frailty have received little attention. It is proposed tha...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2008.02104.x
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVES:To develop and evaluate the psychometric properties of two new urge incontinence-specific instruments that measure quality of life and symptom annoyance. DESIGN:New instruments were developed and validated in racially, ethnically, and age-diverse community-dwelling women with urge or mixed incontinence with...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1999.tb01294.x
更新日期：1999-08-01 00:00:00
abstract：OBJECTIVES:To provide estimates of change in depressive symptoms and determine how changes in depressive symptom influence recovery of functional status. DESIGN:Prospective cohort study. SETTING:Eleven inpatient medical rehabilitation facilities located across the United States. PARTICIPANTS:Five hundred forty-four ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1532-5415.2010.03266.x
更新日期：2011-02-01 00:00:00
abstract：:The reported prevalence of depressive symptomatology among the elderly ranges from 5 to 65 percent in hospital and community populations. Depression is considered the most common emotional disorder of advanced age. One of the chief diagnostic problems has been the lack of differentiation between disorders manifested b...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1980.tb00205.x
更新日期：1980-02-01 00:00:00
abstract：:Caregiving can have a profound effect on the health of the caregiver, yet research on caregiving among American Indians is limited. The purpose of this study was to examine the influence of caregiving on the health-related quality of life (HRQoL) of American Indians enrolled in the Education And Research Towards Healt...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12409
更新日期：2013-09-01 00:00:00
abstract：:A trial by any means that can possibly prevent or retard the development of arteriosclerosis is to be recommended. Arteriosclerosis is the chief cause of strokes and heart attacks. The heavy evening meal now in vogue is characteristically rich in animal fats. Normal digestion is at its peak at about the seventh hour, ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1978.tb02404.x
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVES:To examine concerns that vulnerable populations, such as depressed or cognitively impaired beneficiaries would have challenges accessing Part D coverage. DESIGN:Logistic regression analysis was used to assess whether elderly Medicare beneficiaries with depression or cognitive impairment differentially plann...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2009.02348.x
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVES:To determine whether offspring of centenarians acquired protection from age-related diseases. DESIGN:Case-control study. SETTING:The study was part of the Longevity Genes Project at Albert Einstein College of Medicine. PARTICIPANTS:Centenarians (n=145), offspring of centenarians (n=180), and spouses of th...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52068.x
更新日期：2004-02-01 00:00:00
abstract：:Thirty-eight patients with dementia of various etiologies were studied longitudinally to determine the change in cognition over time in subjects with and without hearing impairment. Hearing impaired subjects were older (P less than .0001), but subject groups were otherwise comparable with respect to living arrangement...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1988.tb04363.x
更新日期：1988-11-01 00:00:00
