Salivary evaluation in radioactive I131 treated patients with thyroid carcinoma.

Abstract:

BACKGROUND AND OBJECTIVE:radioiodine treatment (I131) used to treat thyroid carcinomas produces side effects (sialadenitis, xerostomia, dysphagia and caries susceptibility) reflecting in a poor patient quality of life. This study aimed to evaluate the effect of I131 on salivary function and possible oral impairment. MATERIAL AND METHODS:Thirty-seven patients undergoing I131 were submitted to oral examination, answer questions regarding xerostomia/hyposalivation and collect saliva at three moments (M1: 30-45 days before I131, M2: 1-2 days after I131 and M3: 7-10 days after treatment). Saliva was assayed for flow rate and calcium/phosphate concentrations. RESULTS AND CONCLUSIONS:significant difference in calcium/phosphate concentration was shown between M1 and M2, with evident decrease at M2. Flow rate reduced right after treatment with 41% of patients returning to previous rate at M3 (no statistical difference). A higher number of patients related xerostomia and difficulty in swallowing food at M2. The results showed that xerostomia/hyposalivation, dysphagia and calcium/phosphate concentration decrease may be considered early radioiodine side effects.

journal_name

Acta Odontol Scand

authors

Daniel FI,Lima LD,Grando LJ,Castro R,Cordeiro EAK,Dos Santos CR

doi

10.1080/00016357.2017.1399214

subject

Has Abstract

pub_date

2018-03-01 00:00:00

pages

148-152

issue

2

eissn

0001-6357

issn

1502-3850

journal_volume

76

pub_type

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