Abstract：
OBJECTIVE:Oral leukoplakia (OL) presents as a white lesion of the oral mucosa and is not typically associated with the sensation of pain. OL should be surgically removed when possible because it is considered a potentially malignant oral disorder (PMOD). This study assessed the pain sensations experienced by patients in association with the occurrence and surgical treatment of OL. METHODS:Inclusion criteria were: a clinical diagnosis of OL; biopsy excision; and observation for at least 12 months in the ORA-LEU-CAN study. At the first visit, all the patients were asked about the occurrence of symptoms within the lesion. Ninety-four subjects were assessed over a period of 1 year. All patients underwent complete removal of OL. The patient cohort was divided into three sub-groups: (i) no pain before excision and at the 1-year follow-up; (ii) pain before excision; and (iii) pain at the 1-year follow-up. RESULTS:Overall, pain was reported by 21.3% of the patients at the study start whereas 13.8% of the patients reported pain 1 year after surgical treatment. Patient-reported pain from the lesion at study inclusion was significantly associated with lesions found on the lateral side of the tongue (p=.002). Pain reported by patients one year after surgery was significantly related to female gender (p=.038) and the presence of epithelial cell dysplasia (p=.022). CONCLUSION:We conclude that surgical removal of OL results in a low risk of long-term post-surgical pain. However, OL located on the lateral side of the tongue and in OL with dysplasia are more likely to be associated with pain.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Korytowska M,Schwab G,Giglio D,Hirsch JM,Holmberg E,Kjeller G,Sand L,Wallström M,Öhman J,Braz-Silva P,Hasséus Bdoi
10.1080/00016357.2020.1869826subject
Has Abstractpub_date
2021-01-21 00:00:00pages
1-6eissn
0001-6357issn
1502-3850pub_type
杂志文章abstract：:The purpose of the study was to compare the efficacy of two electric toothbrushes (Philips HP555 and the Philips Jordan 2-action Plaque Remover HP510). A manual toothbrush Jordan V-shaped, medium) served as control. Fifty subjects, aged 18-60 years, participated in a randomized, single-blind, 3 x 3 weeks crossover stu...
journal_title：Acta odontologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/000163500429163
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence and describe the distribution of demarcated opacities and possible consequences of this condition in permanent 1st molars and incisors in Danish children. MATERIAL AND METHODS:Among all 6 to 8-year-old children in two municipalities, 745 (83.6%) were clinically examined for the occ...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016350801926941
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVE:To determine if the differing contrast resolution of various LCD monitors affects the reliability or accuracy of measurements of proposed implant sites. MATERIALS AND METHODS:Edentulous areas of human dry skulls were marked with radiopaque markers in order to standardize the plane of the transverse cross-sec...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016357.2012.741709
更新日期：2013-09-01 00:00:00
abstract：:The aim was to construct and illustrate the use of diagnostic standards for recording of DFS incidence. Separate standards are presented for ranking of subjects; the mean "intermediate" DFS score per subject, which represented the majority decision of three dentists; and a certainty scale for individual tooth surfaces...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016357709055996
更新日期：1977-05-01 00:00:00
abstract：:The paper is a shortened version of a paper read at the symposium on craniofacial growth, in which the literature on various aspects of sutures was reviewed. Suture development, structure, growth, and closure are covered, and the response of sutures to orthopedic forces and their role in craniosynostosis exemplified. ...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章,评审
doi：10.3109/00016359509005965
更新日期：1995-06-01 00:00:00
abstract：:The effect of extrinsic asthma on periodontal conditions was studied in a group of 30 asthmatic children. Clinical examination revealed that asthmatic children had more gingivitis than their healthy controls. The asthmatic children who received an inhaled corticosteroid as treatment had more severe gingivitis compared...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016357909004680
更新日期：1979-01-01 00:00:00
abstract：OBJECTIVE:Gingival fibroblasts (GFs) produce pro-inflammatory cytokines in response to stimulation with lipopolysaccharide (LPS) of Porphyromonas gingivalis, which is thought to be mediated by activation of toll-like receptors (TLR)2 and TLR4. The present study investigated the expression of interleukin (IL)-6, TLR2, a...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016357.2013.834535
更新日期：2014-07-01 00:00:00
abstract：:Ceramic inlays offer a good alternative to posterior composites, which still show a high polymerization shrinkage. The thin cement layer will reduce the total amount of shrinkage and probably result in a better marginal adaptation and decreased marginal leakage. Fired feldspathic ceramic inlays cemented with either a ...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016359409027588
更新日期：1994-06-01 00:00:00
abstract：AIM:The purpose of this clinical study was to evaluate the general incidence of post-operative pain and flare-ups in patients who were endodontically treated by two endodontics specialists using rotary instruments (Hero 642, Micro Mega, France) with the same treatment protocol. METHODS:Records of 382 teeth belonging t...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016357.2012.715199
更新日期：2013-05-01 00:00:00
abstract：:Systemic retinoids are known to cause dryness of the mouth and changes in oral and lip mucosa. The purpose of this study was to evaluate changes in salivary variables during treatment with oral isotretinoin in patients receiving the drug for 3 months for cutaneous acne. Patients were examined 1 month after initiation ...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016359509006003
更新日期：1995-12-01 00:00:00
abstract：:The aim of the study was to evaluate the efficacy of plaque removal of three different toothbrushes on mentally disabled children in two different age groups. A manual triple-headed brush (SuperBrush; Dento Co. AS [junior, regular]) compared with a new manual toothbrush (CrossAction; Oral-B [35 compact, 40 regular]) a...
journal_title：Acta odontologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/00016350410010054
更新日期：2004-12-01 00:00:00
abstract：:This study aimed at determining alveolar bone height in musicians playing wind instruments and non-wind instruments. Two hundred and forty-two subjects, 208 men and 34 women, from 3 national orchestras in Stockholm were examined in an intraoral full-mouth survey. The height of alveolar bone, registered by a computeriz...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016358609026566
更新日期：1986-06-01 00:00:00
abstract：:Candida fungi are frequent in the oral cavity, especially in denture wearers. The infection can cause serious complications in elderly or debilitated subject. The present experimental group consisted of 81 female psychiatric patients (35--91 years of age). In addition to a clinical examination, smears from the palate,...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016357909004708
更新日期：1979-01-01 00:00:00
abstract：:This in vitro study evaluated curing depths of a universal hybrid resin composite with two viscosities (Tetric Ceram and Tetric Flow) after curing with 6 different quartz tungsten halogen and light-emitting diode curing units. Irradiance (light intensity) of the curing units varied between 200 and 700 mW/cm2. The curi...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016350410006905
更新日期：2004-04-01 00:00:00
abstract：IMPORTANCE AND OBJECTIVE:Reactive Oxygen Species (ROS) are oxygen-derived molecules that are unstable and highly reactive. They are important signaling mediators of biological processes. In contrast, excessive ROS generation, defective oxidant scavenging or both have been implicated in the pathogenesis of several condi...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章,评审
doi：10.3109/00016357.2014.954267
更新日期：2015-02-01 00:00:00
abstract：:Causes of traumatic dental injuries were studied in a sample of 321 Finnish children with injured permanent incisors. In girls the most common cause was falls (36.7%), and with boys sports (33.6%). Among the sports accidents, gymnastics dominated for girls and ice hockey for boys. Bicycling was also a markedly frequen...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016358009004714
更新日期：1980-01-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence of dental erosive wear among five-year-olds in Bergen, Norway, and to investigate associations between background factors and the condition. METHODS:A total of 387 children received a dental examination in five Public Dental Service clinics in Bergen, Norway. The parents responded ...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016357.2020.1791357
更新日期：2020-07-21 00:00:00
abstract：:A review of the literature on dental treatment was conducted and models presented of the doctor/dentist-patient relationship. These models are listed and divided into two subgroups, empirical and normative models. The models are scrutinized with focus on the dentist-patient communicative relationship exclusively. Diff...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章,评审
doi：10.3109/00016359709115403
更新日期：1997-04-01 00:00:00
abstract：:Plaque formed during a 5-day xylitol or sucrose chewing gum diet was used as an irritating agent in bone and macrophage culture. The release of hydrolytic enzymes was monitored. The contents of protein, DNA, and ATP were analyzed, to characterize plaque formed during different dietary periods. The release of glycosida...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016358309162320
更新日期：1983-06-01 00:00:00
abstract：:Errors in questionnaire surveys are usually of one of two sources: non-responses or incorrect answers. The aim was to investigate the validity of a questionnaire survey and to estimate the respective bias of these answers. Of 9,283 subjects selected to receive a questionnaire by post, 3,949 (43%) responded, and, of th...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.1080/000163599428643
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVE:Local anesthetics are the most commonly used drugs in dentistry, with a wide range of effects, including antimicrobial activity. High antimicrobial effects have recently been reported on oral microbes from articaine hydrochloride, revealed by the minimum inhibitory concentration and minimal bactericidal conce...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016350802443466
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the smear layer removal and wettability of AH Plus sealer on root canal dentin treated with MA (maleic acid), MA + CTR (cetrimide) and MA + CTR + CHX (chlorhexidine) as final irrigating regimens. MATERIAL AND METHODS:For smear layer removal, 40 teeth were instrumented to size F4 and divided into ...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016357.2017.1402208
更新日期：2018-04-01 00:00:00
abstract：:Corrosion of base metal alloys was studied by placing the alloys in artificial saliva for 2 months and then determining the concentration of metal ions in the saliva. The distribution of the attack on the surface was examined. The results indicated that the amount of metal ions in the artificial saliva could be relate...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016357809004659
更新日期：1978-01-01 00:00:00
abstract：:An index for evaluation of dental wear based on Ryge's system comprising three satisfactory and two not acceptable categories was tested in two different age groups of individuals with brain damage. Group 1 consisted of 12 individuals, 3 women and 9 men, with a mean age of 34.5 years. Group 2 consisted of 13 individua...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016358709096359
更新日期：1987-10-01 00:00:00
abstract：:The purpose of this study was to obtain data on the oral hygiene practices, oral hygiene status, and periodontal health among primary school children in Nairobi. The study group consisted of 513 children, 262 aged 6-8 years and 251 aged 13-15 years. The children were from 6 schools randomly selected among the 154 publ...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016359109005923
更新日期：1991-10-01 00:00:00
abstract：:It was the purpose of the study to test the efficacy of brushing with a 1% chlorhexidine gel or a commercial solution cleanser (Steradent) in preventing formation of plaque on the fitting surface of new dentures. The study group consisted of 74 denture wearers with denture stomatitis who were assigned randomly to one ...
journal_title：Acta odontologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.3109/00016357809027570
更新日期：1978-01-01 00:00:00
abstract：:Microleakage was studied in class-II cavities restored with a calcium hydroxide liner and an adhesive system combined with two different posterior composite resins. The restorations were exposed to repeated loading when immersed in dye solution. The teeth were cut, and microleakage along the cavity walls and into dent...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016359109005915
更新日期：1991-08-01 00:00:00
abstract：:Twenty-one patients, 20 women and 1 man, participated in a controlled study. All patients were diagnosed with primary Sjögren's syndrome (primary SS) according to the Copenhagen and San Diego criteria. The patients were randomly assigned to either a group receiving acupuncture treatment or a control group with no acti...
journal_title：Acta odontologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/00016359850136058
更新日期：1998-04-01 00:00:00
abstract：OBJECTIVE:Periodontitis increases the serum lipopolysaccharide level, contributing to liver injury. Toothbrushing improves periodontitis and may also affect serum lipopolysaccharide concentration and periodontitis-induced liver injury. The purpose of the present study was to examine whether the improvement in periodont...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016350902794818
更新日期：2009-01-01 00:00:00
abstract：:The plaque and gingival condition in 232 Swedish schoolchildren aged 13-14 years has been related to the following predictors; plaque, toothbrushing frequency and technique, bristle stiffness of the toothbrush, smoking habits, use of snuff, social class and sex. Multiple regression analyses have been performed in orde...
journal_title：Acta odontologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016358209024074
更新日期：1982-01-01 00:00:00
