Abstract:
:The ultrastructure of Leishmania aethiopica parasites and their host cells was investigated in lesions of 7 patients suffering from diffuse cutaneous leishmaniasis (DCL) and in lesions of 4 patients with localized cutaneous leishmaniasis (LCL). The appearance of host cells and parasites varied considerably in both disease forms. Host cell variations occurred especially in the number of cytoplasmic vesicles, the size of the parasitophorous vacuoles, and the number of amastigotes per parasitophorous vacuole. Differences concerned the occurrence of a special macrophage-type in DCL-lesions which was characterized by an electron-translucent cytoplasm and a low degree of parasitization, larger parasitophorous vacuoles with higher numbers of amastigotes per vacuole in infected macrophages from DCL-patients, and the number of electron dense granules in host cell vacuoles of DCL-patients. The parasites inducing DCL and LCL significantly differed in size and membrane structure: Amastigotes had a length of 2.27 +/- 0.48 micron and a width of 1.77 +/- 0.40 micron in DCL-lesions, and 1.92 +/- 0.40 micron and 1.48 +/- 0.32 micron in LCL-lesions. Promastigotes obtained from DCL-patients revealed 2078 +/- 308 integral membrane particles (IMP)/micron2 and 892 +/- 246 IMP/micron2 on the P- and E-fracture faces of plasma membranes, while the corresponding values of LCL-derived promastigotes amounted to 1690 +/- 376 IMP/micron2 and 652 +/- 274 IMP/micron2, respectively.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Schurr E,Wunderlich F,Tadesse Gsubject
Has Abstractpub_date
1987-12-01 00:00:00pages
395-407issue
4eissn
0001-706Xissn
1873-6254journal_volume
44pub_type
杂志文章相关文献
ACTA TROPICA文献大全abstract::The Kato-Katz, conventional ethyl-acetate sedimentation, and Midi Parasep(®) methods for diagnosing infection with soil-transmitted helminths were compared. The Kato-Katz technique gave the best overall diagnostic performance with the highest results in all measures (prevalence, faecal egg count, sensitivity) followed...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2013.02.018
更新日期:2013-06-01 00:00:00
abstract::Heartwater caused by Ehrlichia ruminantiumis a disease of domestic and wild ruminants and one of the most economically important tick-borne diseases in Africa. The present study aimed to investigate the occurrence and genetic diversity of E. ruminantium in blood samples from 210 cattle sampled in five districts of Map...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.01.007
更新日期:2019-03-01 00:00:00
abstract::Parenteral quinine is the most frequently used first line treatment for severe Plasmodium falciparum malaria in the developed world. Quinine is known to have a number of toxic side effects including cardiotoxicity, ototoxicity and ocular toxicity. Many therefore advocate routine monitoring of quinine levels for patien...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2005.11.006
更新日期:2006-02-01 00:00:00
abstract::To evaluate the adulticide susceptibility and yearly changes of Anopheles maculipennis Meigen (Diptera: Culicidae) in Thrace, five mosquito populations were evaluated against the resistance status of four different adulticides. Three biochemical resistance mechanisms and yearly changes of activities were investigated....
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2013.02.020
更新日期:2013-06-01 00:00:00
abstract::The food selection behaviour of two fish species indigenous to Zimbabwe (Tilapia rendalli and Sargochromis codringtoni) was studied under laboratory conditions with a view to considering them as biological agents for snail control. Six glass aquaria were set up and divided into two sets each with two aquaria. One S. c...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(95)00144-4
更新日期:1996-05-01 00:00:00
abstract::The water-related exposome is a significant determinant of human health. The disease burden through water results from water-associated communicable and non-communicable diseases and is influenced by water pollution with chemicals, solid waste (mainly plastics), pathogens, insects and other disease vectors. This paper...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2019.03.011
更新日期:2019-05-01 00:00:00
abstract::Five years after a single dose treatment, prevalence, intensity and morbidity of schistosomiasis mansoni were evaluated in Agua Branca, a low endemic community in the South East Brazil (cure rate 94%). At community level, prevalence showed a decrease from 38.9 to 24.5% and the intensity of infection dropped from 119.5...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(01)00190-5
更新日期:2002-02-01 00:00:00
abstract::In vitro cultured Plasmodium falciparum gametocytes were fed to Anopheles gambiae (G3) mosquitoes to identify parasite population characteristics useful for predicting successful mosquito infections. Parameters were collected from an initial study of 90 infections over a two year period and a second study of 55 infect...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(94)90117-1
更新日期:1994-10-01 00:00:00
abstract::With the paradigm shift from the reduction of morbidity and mortality to the interruption of transmission, the focus of malaria control broadens from symptomatic infections in children ≤5 years of age to include asymptomatic infections in older children and adults. In addition, as control efforts intensify and the num...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2011.11.009
更新日期:2012-03-01 00:00:00
abstract::The influence of live Brugia malayi parasites and a Sephadex G-200 fraction of the adult parasite extract (BmAFII) on the progression of Leishmania donovani infection was studied. Inbred hamsters were first infected with B. malayi infective 3rd stage larvae (L3), adult worms or microfilariae (mf), and then with L. don...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2008.01.007
更新日期:2008-05-01 00:00:00
abstract::Access to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptosp...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2007.05.002
更新日期:2007-06-01 00:00:00
abstract::The Japanese Encephalitis (JE) virus circulation in Indonesia was first documented in Lombok in 1960, and the virus was first isolated in 1972 from Culex tritaeniorhynchus in Bekasi, West Java and Kapuk, West Jakarta. Since then, Indonesia has been recognized as an endemic country for JE transmission. Up to now, JE ca...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2018.08.017
更新日期:2018-11-01 00:00:00
abstract::Sodium Antimony Gluconate (SAG) is currently used worldwide as the first-line drugs for the treatment of visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL) since 1940s. Unfortunately, the resistance of Leishmania parasite to this drug is increasing in several parts of the world. The mechanism of drug resista...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2009.01.005
更新日期:2009-04-01 00:00:00
abstract::Visceral leishmaniasis (VL) is a serious and widespread parasitic disease caused by Leishmania donovani complex. The threat of this fatal disease continues due to the lack of ideal drugs or vaccines. In this study, we selected Amastin, CaNA2, Kmp-11 and PDI proteins of Leishmania donovani for study, which are VL vacci...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2018.12.035
更新日期:2019-03-01 00:00:00
abstract::Manipulating the endogenous immune responses of the mosquito such as temporal and spatial expression of antimicrobial peptides may help in the development of a refractory mosquito, unable to transmit malaria. In mosquito several small antimicrobial peptides are activated locally in the midgut and salivary glands upon ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2008.01.001
更新日期:2008-04-01 00:00:00
abstract::The drawback of existing techniques for obtaining intact granulomas and granuloma cells have been, (1) lack of clean intact granulomas without adhering liver tissues, (2) isolating inadequate numbers of clean intact granulomas, and (3) obtaining low numbers of viable granuloma cells from the granulomas. This work aims...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00034-5
更新日期:1998-06-30 00:00:00
abstract::In the presence of light and oxygen, rose bengal causes oxidative damage to Trypanosoma cruzi. The production of lipid hydroperoxides was demonstrated by thin-layer chromatography, and severe ultrastructural alterations compatible with an increased permeability of the cells, which led to gradual osmotic swelling and u...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1984-06-01 00:00:00
abstract::We focused on the epidemiology of alveolar echinococcosis especially in Japan and discussed control measures to prevent an epidemic. No effective control measures against alveolar echinococcosis have been identified thus far because it is difficult to fully understand the ecology of the parasite and its hosts, i.e. th...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2003.09.001
更新日期:2003-12-01 00:00:00
abstract::Visceral leishmaniasis is a life-threatening human disease commonly known as kala-azar. Leishmania donovani is the causative agent of this parasitic disease transmitted by the sand fly vector to infect hosts. Triphenyl tin salicylanilide thiosemicarbazone [Ph(3)Sn(OSal.TSCZH)] (TTST) which is an organometallic complex...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2005.03.008
更新日期:2005-07-01 00:00:00
abstract::Brucellosis is endemic in the Republic of Kazakhstan, particularly in agro-pastoral areas. The purpose of this research is to study the epidemiological situation of brucellosis in livestock recorded in the Republic of Kazakhstan, and to identify the reasons why anti-brucellosis measures were not effective. The researc...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2018.12.028
更新日期:2019-03-01 00:00:00
abstract::Glutathione transferases (GSTs) perform several catalytic and non-catalytic roles in the defense against toxicities of electrophile compounds and oxidative stress, and therefore are involved in stress-response and cell detoxification. Previously, we have provided evidence indicating that EgGST2 and EgGST3, two phyloge...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2018.01.007
更新日期:2018-04-01 00:00:00
abstract::Currently, benzimidazoles are used as chemotherapeutic agents and as a complement to surgery and PAIR in the treatment of cystic echinococcosis (CE). They are generally applied at high doses causing side effects and, 50% of cases do not respond favorably to such chemotherapy. The use of essential oils obtained by dist...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2016.09.001
更新日期:2016-12-01 00:00:00
abstract::The present study performed an analysis of the ultrastructural changes induced by andiroba seed oil in the synganglion of Rhipicephalus sanguineus female ticks, aiming to provide scientific grounds to help in the creation of more specific and efficient methods of control. The synganglion consists of a mass of fused ne...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2014.06.018
更新日期:2015-01-01 00:00:00
abstract::Bashagard is an important malaria endemic area in south of Iran. An epidemiological and entomological survey was performed during 2002-2010. The aim of study was to determine malaria situation, species composition of anopheline mosquitoes and susceptibility status of main vectors to insecticides/larvicides. A total of...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2011.04.017
更新日期:2012-02-01 00:00:00
abstract::Plasma levels of three soluble inducible adhesion molecules, namely: intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1) and endothelial leucocyte adhesion molecule-1 (sELAM-1) or sE-selectin and the pro-inflammatory cytokine, tumour necrosis factor-alpha (TNF-alpha) were measured ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2007.02.011
更新日期:2007-04-01 00:00:00
abstract::Anopheles minimus, an important malaria vector of South East Asia, has reappeared in the Singhbum hills, East-Central India where deforestation and DDT residual spraying had reportedly eliminated it during the Malaria Eradication Programme. The species reported has been identified as sibling species A of the An. minim...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2005.05.013
更新日期:2005-10-01 00:00:00
abstract::China was once a country plagued by parasitic diseases. At the beginning of the founding of the People's Republic of China, nearly 80% of the population suffered from parasitic diseases because of poverty and poor sanitary conditions. After nearly 70 years of development, China has made remarkable achievements in the ...
journal_title:Acta tropica
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.actatropica.2019.105181
更新日期:2019-12-01 00:00:00
abstract::The COVID-19 epidemic spread rapidly through China and subsequently proliferated globally leading to a pandemic situation around the globe. Human-to-human transmission, as well as asymptomatic transmission of the infection, have been confirmed. As of April 03, 2020, public health crisis in China due to COVID-19 was po...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2020.105731
更新日期:2021-01-01 00:00:00
abstract::Arboviruses have become a major public health concern in Brazil, especially after Zika virus (ZIKV) and Chikungunya virus (CHIKV) introduction, leading to massive epidemics. We conducted an investigation of arboviruses in patients with acute febrile illness for less than five days in Mato Grosso state (MT) during the ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2018.12.019
更新日期:2019-02-01 00:00:00
abstract::In an endemic area for Wuchereria bancrofti filariasis in the Nile Delta, survival of adult female Culex pipiens was estimated by parity rate, mosquito infection and infectivity rates. Infection rates and 4th instar larval populations, as well as infection and parity rates, were linearly correlated. Infectivity correl...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(89)90034-x
更新日期:1989-05-01 00:00:00