The Role of Surfactant Therapy in Nonrespiratory Distress Syndrome Conditions in Neonates.

Abstract:

:While treatment of respiratory distress syndrome (RDS) with surfactant in premature neonates is well established, evidence for its use in non-RDS conditions, especially in the term neonate, has been less abundant. The last published review on a PubMed search was in 2001. In this review, we comprehensively and critically evaluated the evidence from the literature regarding the use of surfactant in specific non-RDS disorders in neonates. Surfactant administered as a bolus should be considered in the treatment of meconium aspiration syndrome with progressive respiratory failure. While controversial in congenital diaphragmatic hernia, it should be considered in Group B streptococcal pneumonia. As evidence evolves, we anticipate the broader application and more routine use of surfactant therapy for respiratory failure because of causes other than RDS.

journal_name

Am J Perinatol

authors

Keiser A,Bhandari V

doi

10.1055/s-0035-1556883

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

1-8

issue

1

eissn

0735-1631

issn

1098-8785

journal_volume

33

pub_type

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