Abstract：
STUDY OBJECTIVE:To identify clinical features associated with primary ovarian insufficiency (POI) and collect data on the evaluation and treatment received. DESIGN:Retrospective chart review. Data were abstracted on etiology of POI, history, laboratory evaluation, imaging results, return for clinical care, and treatment plans. SETTING:Urban children's hospital in Cincinnati, Ohio. PARTICIPANTS:Fifty female patients, age 11-26 years, with initial presentation of POI between January 1, 2006 and December 31, 2015. MAIN OUTCOME MEASURES:Etiology of POI, bone mineral density (BMD), laboratory evaluation, and services utilized at presentation. RESULTS:Three hundred thirty-one charts were reviewed, 71 with confirmed diagnosis of POI, and 50 with sufficient data for inclusion. Among the 50, 21 (42%) had Turner syndrome, 18 (36%) remained idiopathic, and 11 (22%) had another condition (eg, autoimmune polyglandular syndrome, galactosemia, etc). Thirty-six (72%) were karyotyped; in 14 (28%), 21-hydroxylase antibodies were measured; 32 (64%) underwent dual-energy x-ray absorptiometry BMD measures of lumbar spine. Eight of 50 patients (16%) reported fracture. Of these, at presentation, 4 (50%) had low BMD, and 2 (25%) had slightly low BMD. On initial spinal dual-energy x-ray absorptiometry, 9 of 32 (28%) had low BMD (Z-score ≤ -2.0) and 7 of 32 (22%) were slightly low (-1.0 to -1.9). All started estrogen therapy within 2 years of presentation. In follow-up, only 2 patients (4%) saw a mental health consultant for emotional support. CONCLUSION:POI is a model of estrogen deficiency with most cases due to Turner syndrome or idiopathic causes. At presentation, many had low BMD and few were seen for psychological support as part of multidisciplinary care.
journal_name
J Pediatr Adolesc Gynecoljournal_title
Journal of pediatric and adolescent gynecologyauthors
Kanj RV,Ofei-Tenkorang NA,Altaye M,Gordon CMdoi
10.1016/j.jpag.2017.07.005subject
Has Abstractpub_date
2018-02-01 00:00:00pages
13-18issue
1eissn
1083-3188issn
1873-4332pii
S1083-3188(17)30314-5journal_volume
31pub_type
杂志文章abstract：STUDY OBJECTIVE:The aim of this study was to measure the prevalence of premature thelarche in infant and toddler girls and to determine if environmental sources of estrogen were associated with early breast development. DESIGN:Observational with mixed methods: Retrospective chart review, cross-sectional component invo...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2011.01.003
更新日期：2011-12-01 00:00:00
abstract：STUDY OBJECTIVE:To document physical and symptomatic changes in adolescent females using depot medroxyprogesterone acetate (DMPA) for contraception. DESIGN:A 30-month prospective experimental study using a convenience sample of subjects. SETTING:A pediatric primary care clinic in Milwaukee, Wisconsin that serves an u...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(97)70039-1
更新日期：1997-02-01 00:00:00
abstract：STUDY OBJECTIVE:We assessed factors that might affect perinatal outcomes in second pregnancies in adolescents. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, MAIN OUTCOME MEASURES: This longitudinal retrospective study was carried out on 66 adolescents who experienced 2 deliveries during their adolescence. Data were col...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2015.05.002
更新日期：2016-02-01 00:00:00
abstract：STUDY OBJECTIVE:To determine if pregnant adolescents interested in group-based prenatal care have different demographic and psychosocial characteristics than those interested in individual prenatal care. Factors that influence the preferred model of prenatal care patients were assessed. DESIGN, SETTING, AND PARTICIPAN...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2015.03.006
更新日期：2015-12-01 00:00:00
abstract：:Most sexually abused children will not have signs of genital or anal injury, especially when examined nonacutely. A recent study reported that only 2.2% (26 of 1160) of sexually abused girls examined nonacutely had diagnostic physical findings, whereas among those examined acutely, the prevalence of injuries was 21.4%...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2017.12.011
更新日期：2018-06-01 00:00:00
abstract：STUDY OBJECTIVE:Latin America ranks second in adolescent birth rate globally. Teenage pregnancy often leads to adverse outcomes, affecting the health of the mother and the child in various ways. We examined the association between sexual and reproductive literacy and teenage pregnancy in Latin America. DESIGN, SETTING,...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2019.06.003
更新日期：2019-10-01 00:00:00
abstract：STUDY OBJECTIVE:To examine our experience with intrauterine device (IUD) use in adolescents and young women. DESIGN:Retrospective descriptive study evaluating outcomes after IUD insertion for patients 21 years or less over an 8-year period. SETTING:Three sites including a Pediatric and Adolescent gynecology private p...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2012.01.005
更新日期：2012-06-01 00:00:00
abstract：:This article reviews typical symptoms of depression presented by adolescents in the reproductive care practice setting, provides an overview of the assessment process, and offers options for referral and/or treatment of this common, yet often unrecognized, mood disorder. Because females have a two-fold higher prevalen...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2007.04.010
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:To preliminarily study the feasibility of oocyte cryopreservation in postpubertal girls aged between 13 and 15 years who were at risk for premature ovarian failure due to the accelerated follicle loss associated with Turner syndrome or cancer treatments. DESIGN:Retrospective cohort and review of literature. ...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2014.01.003
更新日期：2014-12-01 00:00:00
abstract：STUDY OBJECTIVES:Many pediatric providers serving adolescents are not trained to offer comprehensive contraceptive services, including intrauterine devices (IUDs) and implants, despite high safety and satisfaction among adolescents. This study assessed an initiative to train providers at school-based health centers (SB...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2020.07.010
更新日期：2021-02-01 00:00:00
abstract：STUDY OBJECTIVE:To describe and evaluate a Canadian simulation session designed to teach pediatric and adolescent gynecology (PAG) history taking, examination and operative skills, and an approach to the child and adolescent. DESIGN:Obstetrics and gynecology residents in a single academic center participated in a PAG ...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2014.01.105
更新日期：2014-12-01 00:00:00
abstract：STUDY OBJECTIVES:To report a rare reason for primary amenorrhea, a Frasier syndrome, XY gonadal dysgenesis associated with renal failure with eventual development of gonadoblastoma. To study immunohistochemical analysis of gonadoblastoma and dysgerminoma. To analyze the possibility of androgen receptor mutation in this...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(02)00147-x
更新日期：2002-06-01 00:00:00
abstract：STUDY OBJECTIVE:To assess the association between medroxyprogesterone acetate exposure and bone mineral density (BMD) loss and weight change in adolescents. DESIGN:Forty-eight-week prospective, randomized trial conducted May 2012-April 2014. SETTING:Recruitment occurred in the general community and outpatient clinics...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jpag.2016.10.011
更新日期：2017-04-01 00:00:00
abstract：STUDY OBJECTIVE:The objective of this study was to evaluate the quality and accuracy of sexual health information on crisis pregnancy center Web sites listed in state resource directories for pregnant women, and whether these Web sites specifically target adolescents. DESIGN:A survey of sexual health information prese...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2015.05.008
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:The objective of this research was to examine the effectiveness of a brief behavioral intervention, provided at the time of diagnosis of pelvic inflammatory disease, on subsequent behaviors by patients who were urban adolescents in a community in which sexually transmitted infection was prevalent. METHODS:12...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.jpag.2009.06.005
更新日期：2010-04-01 00:00:00
abstract：STUDY OBJECTIVE:The diagnostic and treatment tools used in breast centers are largely geared to adults, and there is little consideration of the unique characteristics of breast diseases in younger age groups. Herein we report on the preliminary experience of a specialized breast clinic for children and adolescents. D...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2019.08.010
更新日期：2020-02-01 00:00:00
abstract：STUDY OBJECTIVE:Mycoplasma genitalium (MG) is a sexually transmitted pathogen linked to female morbidity, but testing for MG is not standardized. We aimed to determine which point-of-care (POC) vaginal tests could predict MG infection. DESIGN, SETTING, PARTICIPANTS:A cross sectional study recruited sexually active ado...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2012.09.005
更新日期：2013-02-01 00:00:00
abstract：STUDY OBJECTIVE:To characterize Müllerian anatomy in 46,XX cloacal exstrophy patients. DESIGN:Retrospective review of prospectively maintained, institutionally approved exstrophy-epispadias-cloacal exstrophy database. SETTING:Tertiary care, high-volume exstrophy center (Division of Pediatric Urology, The Johns Hopkin...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2016.01.124
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:Alkaline batteries are known to cause caustic burns to the esophagus when ingested. We report a case of alkaline burns to the vagina. CASE:A 13-year-old female presented to the Emergency Department with abdominal pain. She was admitted for necrotic vaginal burns after batteries were removed from her vagina....
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2008.10.009
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:Juvenile cystic adenomyomas (JCAs) are rare uterine lesions. Differential diagnosis might be difficult. We present the case of an adolescent who was diagnosed with JCA and was managed with laparoscopic excision. CASE:A 14-year-old patient with complaint of menarche with excruciating dysmenorrhea, was diagno...
journal_title：Journal of pediatric and adolescent gynecology
pub_type：
doi：10.1016/j.jpag.2020.08.010
更新日期：2020-12-01 00:00:00
abstract：STUDY OBJECTIVE:Adolescent compliance with cytologic and histologic cervical abnormalities is poor. Recent changes in abnormal cytology follow-up and colposcopy indications in young women may delay the diagnosis of cervical dysplasia. The objective of our study was to determine the compliance with follow up. We also wa...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2008.08.003
更新日期：2009-06-01 00:00:00
abstract：STUDY OBJECTIVE:To determine the suitability and efficacy of methotrexate (MTX) therapy for adolescent patients with ectopic pregnancy. MATERIALS:Patients with ectopic pregnancy were treated with methotrexate, 50 mg/m2 intramuscularly. Follow-up determinations of quantitative beta hCG levels were done on days 1, 4, an...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(96)70013-x
更新日期：1996-04-01 00:00:00
abstract：STUDY OBJECTIVE:To describe the prevalence and correlates of vaginal douching among urban African American adolescents and to examine the association between douching and sexually transmitted infection (STI) status. DESIGN:Demographic, psychosocial, and behavioral data were collected through cross-sectional, self-admi...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2011.07.017
更新日期：2012-02-01 00:00:00
abstract：STUDY OBJECTIVE:Survival into adulthood is now a reality for many adolescents facing cancer. Fertility preservation (FP) is rapidly advancing, but oncology providers and health systems struggle to incorporate the newest FP technologies into the clinical care of adolescents. Our objective was to systematically review an...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2016.04.005
更新日期：2016-12-01 00:00:00
abstract：STUDY OBJECTIVE:Education materials detailing fertility preservation options geared towards pediatric oncology patients are inadequately available, particularly materials that are culturally tailored. An English language pediatric fertility preservation brochure was developed in 2011, and given the significance of fami...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2013.10.004
更新日期：2014-08-01 00:00:00
abstract：STUDY OBJECTIVE:To investigate the impact of operating surgeon specialty on rates of ovarian preservation, and to explore differences in surgical management when malignant lesions are identified. DESIGN:Retrospective study. SETTING:Education and research hospitals. PARTICIPANTS:Between January 1, 2003 and January 1,...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2011.03.012
更新日期：2011-10-01 00:00:00
abstract：:Over a 2-month period, a 16-yr-old African-American female presented with recurrent episodes of severe, migratory limb pain. Sickle cell C disease was ultimately diagnosed. She adamantly denied sexual activity but was found to be 28 weeks pregnant. Her limb pain was probably triggered by the metabolic and hemodynamic ...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(01)00149-8
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:Juvenile granulosa cell tumors (JGCT) are rare ovarian tumors that frequently present with precocious puberty. Presentation in infants less than a year of age is also rare. CASE:We describe a 10-month-old infant who presented with both premature thelarche and adrenarche due to JGCT. Laboratory evaluation re...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2008.08.001
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:Acute lymphoblastic leukemia is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace normal marrow hematopoietic cells, resulting in a marked decrease in the production of normal blood cells. CASE REPORT:We report a case of isolated ovarian relapse 7 years after ...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2008.05.007
更新日期：2009-08-01 00:00:00
abstract：:Background: One of the variables most consistently associated with vaginal douching is race, with African-American women douching more regularly. Sparse data exists in the medical literature about the practice of vaginal douching among adolescents. The purpose of this study was to assess the prevalence, knowledge, att...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(00)00024-3
更新日期：2000-05-01 00:00:00
