Abstract：
STUDY OBJECTIVE:The diagnostic and treatment tools used in breast centers are largely geared to adults, and there is little consideration of the unique characteristics of breast diseases in younger age groups. Herein we report on the preliminary experience of a specialized breast clinic for children and adolescents. DESIGN:Retrospective, observational. SETTING:Pediatric Surgical Breast Clinic of Schneider Children's Medical Center of Israel. PARTICIPANTS:Patients referred to the clinic during the first 18 months of its establishment. INTERVENTIONS AND MAIN OUTCOME MEASURES:Rate of breast masses, rate of malignancy, and types of evaluation and treatment. RESULTS:Forty-seven patients aged 0-19 years were referred. Breast masses were suspected in 23/47 (48.9%) and confirmed using ultrasound in 14/47 (29.7%; mean age, 16.4 years), followed by needle core biopsy in 7. Seven patients had multiple masses. Breast Imaging and Reporting Data System scores ranged from 3 to 4b. All cases were treated as fibroadenomas. Four patients underwent surgery because of a large mass (>5 cm; n = 3) or patient's preference to remove the lump rather than follow-up (n = 1). There were no malignancies. The median time from patient identification of the mass until seeking medical help was 5 months. CONCLUSION:Several findings distinct to this age group were highlighted: high rate of multiple masses, lack of malignancy, and high risk of delayed diagnosis. Care should be taken when using Breast Imaging and Reporting Data System categorization because it was formulated for adults and might be very limited in the adolescent population. Longer-term studies of larger cohorts are planned.
journal_name
J Pediatr Adolesc Gynecoljournal_title
Journal of pediatric and adolescent gynecologyauthors
Cohen O,Avinadav E,Sharon E,Pirogovsky A,Freud Edoi
10.1016/j.jpag.2019.08.010subject
Has Abstractpub_date
2020-02-01 00:00:00pages
23-26issue
1eissn
1083-3188issn
1873-4332pii
S1083-3188(19)30266-9journal_volume
33pub_type
杂志文章abstract：OBJECTIVE:To investigate the effects of 4-month treatment of medroxyprogesterone acetate (MPA) and Diane-35 on the clinical and biochemical features of hyperandrogenism and quality of life of adolescent girls with polycystic ovarian syndrome (PCOS). DESIGN:A prospective, randomized, cross-over study. SETTING:An accre...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jpag.2013.09.011
更新日期：2014-06-01 00:00:00
abstract：STUDY OBJECTIVE:To assess the effect of providing standardized counseling to improve the rates of contraception initiation and utilization among detained young women. This was a quality improvement (QI) project conducted at a large urban juvenile short-term detention center. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
abstract：STUDY OBJECTIVE:Survivors of childhood malignancy may be at increased risk for HPV infection for biological and cognitive/behavioral reasons. HPV vaccination is currently recommended for females 11-12 years old with catch up vaccination up to age 26 years. The objective of this cross-sectional study was to determine th...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2012.05.004
更新日期：2012-10-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate the association between maternal body mass index and neonatal outcomes in adolescents and to compare neonatal outcomes between overweight and obese adolescents and obstetric low-risk adult women. DESIGN:Retrospective cohort study using data from the Swedish Medical Birth Register. SETTING:...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
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更新日期：2019-04-01 00:00:00
abstract：STUDY OBJECTIVE:To characterize menstrual health issues and their effect in young women with Angelman syndrome (AS). Our secondary objective was to compare them with young women with autism spectrum disorders (ASDs). DESIGN:Cross-sectional convenience sample survey. SETTING:An institutional review board-approved Web-...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2015.12.004
更新日期：2016-08-01 00:00:00
abstract：STUDY OBJECTIVE:To test associations and interactions between racial identification, neighborhood risk, and low birth weight disparities between infants born to African-American and white adolescent mothers. DESIGN:Retrospective cross-sectional study. Birth cases were geocoded and linked to census tract information fr...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2015.08.004
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:To describe attitudes and perceptions toward acceptability of human papilloma virus (HPV) vaccination among inner city Caribbean (CA) and African American (AA) adolescents and their parents, and discuss correlates that may be associated with these factors. DESIGN:Questionnaire survey. SETTING:An adolescent ...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2010.02.002
更新日期：2010-08-01 00:00:00
abstract：STUDY OBJECTIVES:To determine the impact of antiandrogen treatment on bone density and geometry. DESIGN:Prospective cohort investigation. SETTING:Academic research institute. PARTICIPANTS:38 (age 14.96 ± 1.42 yr) subjects with PCOS. INTERVENTIONS:Treated with metformin (n = 17) or metformin and antiandrogen (n = 21...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2011.11.010
更新日期：2012-06-01 00:00:00
abstract：:This review examines the prevalence, associated morbidity, and treatment of primary dysmenorrhea in adolescent girls. Relevant literature was examined by systematic, evidence-based review using MEDLINE and Cochrane Collaboration databases. Dysmenorrhea is highly prevalent during adolescence. Despite differences in mea...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/s1083-3188(00)00076-0
更新日期：2001-02-01 00:00:00
abstract：:A laparoscopic technique is reported as an operative approach for gonadectomy in a case of testicular feminization syndrome. A 17-year-old phenotypic female presented with primary amenorrhea and was evaluated through a diagnostic protocol that included clinical, cytogenetic, and hormonal examinations. The findings sup...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(99)00032-7
更新日期：2000-02-01 00:00:00
abstract：STUDY OBJECTIVE:The aim of our study was to determine the etiologic distribution of 46,XX disorder of sexual development (DSD) according to the new DSD classification system and to evaluate the clinical features of this DSD subgroup in our patient cohort. PARTICIPANTS:The evaluation criteria and clinical findings of 9...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2014.01.106
更新日期：2015-02-01 00:00:00
abstract：STUDY OBJECTIVE:Latin America ranks second in adolescent birth rate globally. Teenage pregnancy often leads to adverse outcomes, affecting the health of the mother and the child in various ways. We examined the association between sexual and reproductive literacy and teenage pregnancy in Latin America. DESIGN, SETTING,...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2019.06.003
更新日期：2019-10-01 00:00:00
abstract：STUDY OBJECTIVE:To evaluate the incidence of hemostatic disorders in a population of adolescents with various patterns of abnormal uterine bleeding (AUB). DESIGN:Retrospective observational study. SETTING:University hospital. PARTICIPANTS:One hundred thirteen adolescents with AUB; mean age at menarche and mean age a...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2013.06.003
更新日期：2013-10-01 00:00:00
abstract：STUDY OBJECTIVE:To describe repeat pregnancy among adolescents and to compare those who experienced a repeat pregnancy to those who did not. DESIGN, SETTING, PARTICIPANTS:Retrospective case control of all adolescents who entered and exited the Teen Mother & Child Program, a multidisciplinary clinic for pregnant and pa...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(03)00011-1
更新日期：2003-04-01 00:00:00
abstract：STUDY OBJECTIVE:Survival into adulthood is now a reality for many adolescents facing cancer. Fertility preservation (FP) is rapidly advancing, but oncology providers and health systems struggle to incorporate the newest FP technologies into the clinical care of adolescents. Our objective was to systematically review an...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2016.04.005
更新日期：2016-12-01 00:00:00
abstract：STUDY OBJECTIVE:Congenital uterine anomalies are common, although the majority are asymptomatic. When an obstructed system exists, women may present with abdominal pain, or dysmenorrhea. Removal of the obstructed horn may be required in the symptomatic patient. In the past, surgical treatment necessitated a laparotomy....
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2006.08.003
更新日期：2007-06-01 00:00:00
abstract：STUDY OBJECTIVE:To report results of a retrospective multicentric Italian survey concerning the management of pediatric ovarian torsion (OT) and its recurrence. DESIGN:Multicenter retrospective cohort study. SETTING:Italian Units of Pediatric Surgery. PARTICIPANTS:Participants were female aged 1-14 years of age with...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jpag.2016.11.008
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:Despite hypothesized relationships between lack of partner support during a woman's pregnancy and adverse birth outcomes, few studies have examined partner support among teens. We examined a potential proxy measure of partner support and its impact on adverse birth outcomes (low birth weight (LBW), preterm birt...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2013.08.002
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to further evaluate the pathologic features of epithelial ovarian neoplasms and their relative frequency among all ovarian tumors in the adolescent population. DESIGN:We conducted a retrospective pathologic study of all cases of epithelial ovarian neoplasms in adolescents (aged 11-...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2011.07.011
更新日期：2011-12-01 00:00:00
abstract：:Epithelial ovarian tumors are uncommon before 20 years of age and rarely occur before puberty. The vast majority of these tumors are benign, and few cases of malignant and borderline tumors are described. We report a case of a 4-year-old premenarchal girl, previously healthy, who presented with two abdominal masses. L...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2009.08.008
更新日期：2010-02-01 00:00:00
abstract：STUDY OBJECTIVE:To describe an unusual, premenarchal presentation of an obstructive vaginal anomaly. DESIGN:Case Report. SETTING:University Medical Center. PARTICIPANTS:Premenarchal subject INTERVENTIONS:Vaginogram, vaginal septum resection. RESULTS:Vaginal septum resection with resolution of vaginal discharge. C...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2005.09.008
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Juvenile granulosa cell tumors (JGCT) are rare ovarian tumors that frequently present with precocious puberty. Presentation in infants less than a year of age is also rare. CASE:We describe a 10-month-old infant who presented with both premature thelarche and adrenarche due to JGCT. Laboratory evaluation re...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2008.08.001
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:A rare disorder of sex development is 45,X/46,XY mosaicism, which is phenotypically very heterogenous, ranging from normal male (or female) to that of genital ambiguity of varying degrees. CASE:We report a case of a neonate with 45,X/46,XY mosaicism and hydrocolpos, and we point out the dilemma and the diff...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2018.09.001
更新日期：2019-02-01 00:00:00
abstract：STUDY OBJECTIVE:To describe the prevalence and characteristics of advanced stage endometriosis in adolescents and young women treated in a tertiary referral center. DESIGN:Retrospective cohort. SETTING:Tertiary referral center. PATIENTS AND INTERVENTIONS:86 adolescents and young women (≤22 y) who underwent surgery f...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2013.12.010
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Antenatally diagnosed abdominal cysts are common, and frequently are ovarian in origin, which usually regress spontaneously. Surgery is indicated in the infantile period in case of very large, persisting or symptomatic cysts. Many surgeons feel that watchful waiting can be justified in newborns with simple a...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2007.09.003
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:Endometriosis-ectopic implantation of endometrial-like tissue-affects 10% of female adolescents and adults. First-line treatment includes progesterone only (such as norethindrone acetate [NET-A]) or combined estrogen/progestin oral contraceptive pills. Estrogen-containing contraceptives confer increased risk...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2016.12.002
更新日期：2017-06-01 00:00:00
abstract：STUDY OBJECTIVE:To examine the etiology of MURCs anomalies and the management of a patient with these anomalies as well as cardiac and anorectal abnormalities causing primary amenorrhea and abdominal pain. DESIGN:Case study. RESULT:Relief of pelvic pain following GnRH agonist therapy and continuous oral contraceptive...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/s1083-3188(02)00161-4
更新日期：2002-08-01 00:00:00
abstract：STUDY OBJECTIVE:To provide initial insight into physical activity patterns and predictors of moderate to vigorous physical activity (MVPA) in youth with polycystic ovary syndrome (PCOS) by using a multisensor activity monitor. DESIGN:Cross-sectional study analyzing baseline MVPA data using real-time continuous monitor...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2014.10.010
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Skene's glands are believed to be homologues of the prostate gland derived from the urogenital sinus.(1) Complications of Skene's glands occur most often in the third and fourth decades and are rarely seen in premenarchal females. CASE:A 3-year-old presented to her pediatrician with a 9-day complaint of vul...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2007.11.004
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:Fibroepithelial polyps (FEPs) are benign tumors, of possibly hormone-dependent nature, found in the vulvovaginal region of women of reproductive age. CASE:A 15-year-old adolescent girl, receiving hormonal contraceptive therapy, who presented with multiple vulvar masses with histopathology consistent with FE...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2017.04.004
更新日期：2017-10-01 00:00:00
