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Chemistry Is Dead. Long Live Chemistry!

Abstract：

:Chemistry, once king of fluorescence microscopy, was usurped by the field of fluorescent proteins. The increased demands of modern microscopy techniques on the "photon budget" require better and brighter fluorophores, causing a renewed interest in synthetic dyes. Here, we review the recent advances in biochemistry, protein engineering, and organic synthesis that have allowed a triumphant return of chemical fluorophores to modern biological imaging.

journal_name

Biochemistry

journal_title

Biochemistry

authors

Lavis LD

doi

10.1021/acs.biochem.7b00529

subject

Has Abstract

pub_date

2017-10-03 00:00:00

pages

5165-5170

issue

39

eissn

0006-2960

issn

1520-4995

journal_volume

56

pub_type

杂志文章,评审

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