[The kinetics of bacterial killing by fluctuating concentrations of antibiotics].

Abstract:

:Differences in kill kinetics and the regrowth pattern of bacteria under the influence of various antibiotics are frequently not represented by their MIC values. The area under the concentration curve represents antimicrobial activity more accurately than the peak concentration. Readministration of antibiotics should occur prior to bacterial regrowth for optimal efficacy. When administering combinations of antibiotics non-simultaneous dosing is superior to simultaneous administration.

journal_name

Wien Klin Wochenschr

authors

Guggenbichler JP,Allerberger F,Bonatti H,Semenitz E,Dierich MP

subject

Has Abstract

pub_date

1989-03-31 00:00:00

pages

224-9

issue

7

eissn

0043-5325

issn

1613-7671

journal_volume

101

pub_type

杂志文章
  • [Glomerular prostaglandins: synthesis, mechanism of action and interaction with ACE inhibitors].

    abstract::Prostaglandins (PG) play an important role in the regulation of the renal blood flow and glomerular filtration rate. This study was designed to examine PG synthesis in the presence and absence of the ACE inhibitor captopril, PG binding to specific receptors and the ability of PG to stimulate cAMP accumulation in isola...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Stetina Z

    更新日期:1991-01-01 00:00:00

  • Noninvasive screening for liver fibrosis and portal hypertension by transient elastography--a large single center experience.

    abstract:BACKGROUND:Transient elastography (TE) is a noninvasive tool to assess hepatic fibrosis by measuring liver stiffness (LS). Recent studies suggest that TE may be used to screen for liver cirrhosis and clinically significant portal hypertension (≥ 10 mmHg; CSPH), whereas data on the clinical applicability of TE are limit...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-012-0190-5

    authors: Reiberger T,Ferlitsch A,Payer BA,Pinter M,Schwabl P,Stift J,Trauner M,Peck-Radosavljevic M

    更新日期:2012-06-01 00:00:00

  • [Pathophysiology and therapy of diabetic ketoacidosis and of non-ketoacidotic hyperosmolar diabetic coma].

    abstract::Metabolic derangements in diabetic coma are the sequelae of insulin deficiency. These defects are aggravated by the actions of insulin counteracting ("diabetogenic") hormones and hypertonic dehydration, which both impair insulin action. Conversely, it has been shown that hypo-osmolar rehydration of a hyperosmolar, sev...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Waldhäusl W,Kleinberger G,Bratusch-Marrain P,Komjati M

    更新日期:1984-04-27 00:00:00

  • [Strategies for the diagnosis of lysosomal storage diseases: symptoms, methods and samples].

    abstract::Lysosomal diseases are a group of about 30 genetic defects with a total incidence of 3 to 4 cases/10,000 newborns. Their clinical appearance is very heterogeneous and comprises infantile, as well as juvenile or adult forms. Our concept for their diagnosis has now been in use for eight years and entails the following s...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Paschke E,Stöckler S

    更新日期:1992-01-01 00:00:00

  • [Endocrine constellation in androgenetic alopecia in the female].

    abstract::The mechanisms which induce androgenetic alopecia in females are only poorly understood at the molecular biological level. In predisposed, mainly centroparietal areas, androgenic stimulation of genetically predisposed hair follicles is considered to cause transformation from terminal to vellus hair follicles. However,...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Schmidt JB

    更新日期:1987-01-09 00:00:00

  • [Initial experiences with the neodym YAG laser in urology].

    abstract::The present study reports the therapeutic results obtained by using neodym-YAG laser for the coagulation of tumours of the external genitals (n = 30), as well as for endoscopic laser treatment of tumours of the bladder (n = 32) and the urethra (n = 2). Despite the small number of cases, laser treatment of bladder tumo...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Maier U,Kautzky W

    更新日期:1984-01-20 00:00:00

  • Prediction of success in the first-year exam in the study of medicine--a prospective survey.

    abstract:OBJECTIVE:To identify predictors of students' success in the first-year exam in a new curriculum in the study of medicine in Vienna. DESIGN:We tested 11 topics (including socio-demographic variables, family background, school performance, economic situation, living conditions, social integration and health, learning c...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-005-0477-x

    authors: Haidinger G,Frischenschlager O,Mitterauer L

    更新日期:2005-12-01 00:00:00

  • [Changes in the treatment of urogenital tuberculosis].

    abstract::Potent antituberculosis drugs and new endourological measures have changed the concept of management of urogenital tuberculosis. This paper presents a report on 56 patients treated with rifampicin, ethambutol and isoniazid for 1 year. Therapy was started in hospital and continued on an ambulatory basis. Reconstructive...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Lipsky H,Stadler W

    更新日期:1988-09-09 00:00:00

  • Insulinoma induced hypoglycemia in a type 2 diabetic patient.

    abstract::Insulinoma in a patient with pre-existing diabetes mellitus is extremely rare. We report a case of an insulinoma in a patient with type 2 diabetes mellitus who after 14 years of sulfonylurea treatment experienced recurrent episodes of hypoglycemia. Endogenous hyperinsulinism was confirmed and endoscopic ultrasonograph...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Ravnik-Oblak M,Janez A,Kocijanicic A

    更新日期:2001-04-30 00:00:00

  • Influences of hydrocortisone therapy on arginine vasopressin plasma levels in septic shock.

    abstract::Concomitant hydrocortisone and arginine vasopressin therapy increases arginine vasopressin plasma levels and may improve survival in septic shock. The objective of this post hoc analysis of a prospective study was to determine whether hydrocortisone therapy increases arginine vasopressin plasma levels in patients with...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-011-1568-5

    authors: Jochberger S,Dünser MW

    更新日期:2011-04-01 00:00:00

  • Body mass index and height in 11- to 16-year-old Austrian students attending two different school types with divergent socioeconomic backgrounds.

    abstract:BACKGROUND:In developed countries high socioeconomic status (SES) is associated with lower body mass index (BMI) and greater height compared with low SES. AIM:To investigate differences in BMI/height in adolescent students from two different school types with divergent SES backgrounds. METHODS:A total of 4579 student...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-019-1479-4

    authors: Riedl S,Riedl-Schlauss V,Häusler G,Gleiss A

    更新日期:2019-07-01 00:00:00

  • [Calcium channel mediated calcium release from the rabbit skeletal muscle sarcoplasmic reticulum vesicle].

    abstract::Activation and inhibition of the calcium release channel of rabbit skeletal muscle heavy sarcoplasmic reticulum (HSR) was investigated by various methods. The calcium release channel is activated by binding of calcium in the micromolar range and by binding of adenine nucleotides in the millimolar range. Ruthenium red ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Suko J,Wyskovsky W,Hohenegger M,Plank B,Bertel O,Klein S,Hellmann G

    更新日期:1990-10-26 00:00:00

  • [Moducrin--a new combined preparation in the treatment of hypertension (author's transl)].

    abstract::A product combining 25 mg hydrochlorothiazide, 2.5 mg amiloride hydrochloride and 10.0 mg timolol maleate (Moducrin) was tested in 20 previously untreated hypertensive persons. The systolic blood pressure before treatment was 199.1 +/- 24.8 mmg Hg and after treatment 149.1 +/- 19.1 mm Hg. Diastolic blood pressure show...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Prachar H,Nobis H,Pollak H,Enenkel W

    更新日期:1981-08-07 00:00:00

  • [The place of laparoscopy in the investigation of infertility (author's transl)].

    abstract::An assessment of the value of hysterosalpingography (HSG) and laparoscopy was made on the basis of a comparison of the respective findings obtained during routine investigation of 105 women attending the Infertility Clinic. The results of the two procedures concurred in 76% of the women; in the remaining cases, appare...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Schmid R,Schneider WH

    更新日期:1978-02-17 00:00:00

  • [Lacrimal duct reconstruction in tumor surgery and following trauma].

    abstract::Traumatic injuries of the lid often affect the lower lid and the lower canaliculus. Lid destruction by tumours also frequently takes place in the medial part of the lower lid, involving the canaliculus inferior. In order to prevent chronic epiphora the lower canaliculus has to be reconstructed. The most elegant and ef...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Steinkogler FJ

    更新日期:1985-08-09 00:00:00

  • Differences in risk factors for coronary heart disease in patients from continental and Mediterranean regions of Croatia.

    abstract:BACKGROUND:There are few data on differences in exposure to risk factors for coronary heart disease (CHD) in relation to geographic areas, especially areas with large differences in terms of continental and Mediterranean climates. To study these differences in Croatia, we analyzed data from the Treatment and Secondary ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00508-008-1065-7

    authors: Bergovec M,Reiner Z,Milicić D,Vrazić H

    更新日期:2008-01-01 00:00:00

  • [Treatment of infertile couples--an interdisciplinary task (author's transl)].

    abstract::The results obtained by closest cooperation between gynaecologist and andrologist in the treatment of sterile marriages are reported. 127 couples were treated over a period of 20 months. Almost 100% of the males and 60% of the females were sub- or infertile. Treatment of both partners was meticulously coordinated in o...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Grünberger W,Schneider WH,Maier U,Stackl W,Lunglmayr G

    更新日期:1980-05-09 00:00:00

  • Low dose intravenous immunoglobulin in addition to cyclophosphamide in systemic sclerosis : Single centre experience.

    abstract:AIM:Systemic sclerosis (SSc) is a rare chronic disease characterized by pathologic collagen deposits in the skin and internal organs. Although it is considered to be an autoimmune disease, immunosuppressants have a limited effect on severe SSc. Intravenous immunoglobulins (IVIG) have shown favorable effects in patients...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-020-01669-y

    authors: Perković D,Petrić M,Božić I,Borić K,Marasović Krstulović D,Radić M,Martinović Kaliterna D

    更新日期:2020-05-25 00:00:00

  • Profile of SARS-CoV-2.

    abstract::The recent emergence of a new coronavirus (severe acute respiratory syndrome coronavirus‑2, SARS-CoV-2) that is transmitted efficiently among humans and can result in serious disease and/or death has become a global threat to public health and economy. In this article, we describe some of the most important characteri...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-020-01763-1

    authors: Heinz FX,Stiasny K

    更新日期:2020-11-01 00:00:00

  • [Opinion of the Austrian Society of Radiology and the Austrian Society of Pneumology].

    abstract::The National Lung Screening Trial (NLST) could demonstrate, for the first time, in a prospective randomized trial, that low-dose CT screening (LD-CT) may decrease lung cancer mortality. At the moment, it is unclear how these results will be applicable to Austria. Specifically, the definition of the population at an in...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-013-0356-9

    authors: Prosch H,Studnicka M,Eisenhuber E,Olschewski H,Stiefsohn E,Hartl S,Herold C,Burghuber O,Mostbeck G,Vorstände der Österreichischen Röntgengesellschaft, Gesellschaft für Medizinische Radiologie und Nuklearmedizin und der Österreichischen

    更新日期:2013-06-01 00:00:00

  • [Effect of bezafibrate in isolated hypercholesterolemia and mixed hyperlipidemia on infarct risk (Stepwise Program for Individual Risk Identification and Therapy): an open multicenter study].

    abstract::The therapeutic effect of bezafibrate (1 x 400 mg/day) on plasma lipids and coronary risk was evaluated in an open, prospective multicenter study in 763 patients with isolated hypercholesterolemia or mixed hyperlipidemia. During the 16 weeks of treatment (712 patients were included in the evaluation) bezafibrate lower...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Sinzinger H,Virgolini I,Kudlacek P

    更新日期:1991-01-01 00:00:00

  • Prevalence of vertebral fractures in an urban population in Croatia aged fifty and older.

    abstract:AIM OF THE STUDY:To establish the prevalence of vertebral fractures according to age groups, sex and vertebral level in a sample of a Croatian urban population aged > or =50. We also tried to establish how many people had been diagnosed with osteoporosis by their family physician. PARTICIPANTS AND METHODS:Lateral thor...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s00508-004-0292-9

    authors: Grazio S,Korsić M,Jajić I

    更新日期:2005-01-01 00:00:00

  • Management and outcome of traumatic subdural hematoma in 47 infants and children from a single center.

    abstract:BACKGROUND:Traumatic brain injury (TBI) is a frequent cause of mortality and acquired neurological impairment in children. It is hypothesized, that with the adequate treatment of SDH in children and adolescence, excellent clinical and functional outcomes can be achieved. The aim of this study was to present the severit...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-020-01648-3

    authors: Binder H,Tiefenboeck TM,Majdan M,Komjati M,Schuster R,Hajdu S,Leitgeb J

    更新日期:2020-09-01 00:00:00

  • [Myasthenia gravis and sleep].

    abstract::In myasthenia gravis respiratory function is often disturbed in the night, especially during REM sleep, despite of normal daytime respiratory function. Nevertheless, nocturnal respiratory problems are rarely diagnosed. Sleepiness, concentration and memory problems can be symptoms of a sleep related breathing disorder....

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Stepansky R,Zeitlhofer J

    更新日期:2001-04-17 00:00:00

  • [Prevalence and severity of bronchial asthma, allergic rhinitis and atopic dermatitis in Salzburg school children].

    abstract::As part of the International Study of Asthma and Allergies in Childhood (ISAAC), the aim of our study was to determine the prevalence and severity of asthma, allergic rhinitis and eczema in Austrian schoolchildren, using an international standardised protocol. A questionnaire concerning symptoms and prior diagnosis of...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Eder W,Gamper A,Oberfeld G,Riedler J

    更新日期:1998-10-16 00:00:00

  • The role of local anaesthetic inhalation during premedication before bronchoscopy.

    abstract::In a prospective randomized study, the efficacy of local anaesthetic inhalation during premedication before bronchoscopic examination was evaluated. Eighty patients with chronic nonproductive cough were inhaling either nebulized anaesthetics (10 ml of 1% trimecain; 40 patients--group A) or an isotonic chlorine solutio...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Salajka F

    更新日期:1999-12-23 00:00:00

  • [Diabetes and pregnancy: treatment and results (author's transl)].

    abstract::Pregnancy and delivery in 190 diabetic women are described. Obstetric, medical and neonatal guidelines for treatment are outlined and the following results are reported: 1. The delivery dates suggested by P. White were generally exceeded by 2 weeks. Group A was delivered at term, group B generally in the 38th week, gr...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Artner J,Baumung H,Bruneder H,Irsigler K,Korp W,Lantzberg F,Ogris E,Pollauf F,Rosenkranz A,Sedlak W

    更新日期:1977-09-16 00:00:00

  • Treatment of partial thickness burns of the face with Acticoat7™ : A retrospective single center study.

    abstract:BACKGROUND:The face is affected in more than 50% of patients with extensive burn trauma. Effective treatment is of importance to avoid hypertrophic scarring, functional impairment and social stigmatization. MATERIAL AND METHODS:All patients treated with Acticoat7™ due to superficial and deep partial thickness burns of...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-020-01757-z

    authors: Nedomansky J,Oramary A,Nickl S,Fuchs G,Radtke C,Haslik W,Fochtmann-Frana A

    更新日期:2020-10-30 00:00:00

  • The effect of upper gastrointestinal system endoscopy process on serum oxidative stress levels.

    abstract::Some authors have investigated the effects of oxidative stress in some process such as undergoing laparoscopic. However, the effect of upper gastrointestinal system endoscopy process on oxidative stress is unclear. We evaluated the short-term effect of upper gastrointestinal system endoscopy process on oxidative stres...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-015-0752-4

    authors: Turan MN,Aslan M,Bolukbas FF,Bolukbas C,Selek S,Sabuncu T

    更新日期:2016-12-01 00:00:00

  • [Benefits and risks of physical activity in patient with coronary heart disease].

    abstract::Endurance training after myocardial infarction results in increased fitness and favours regression of coronary arteriosclerosis if the intensity of the training programme results in an expenditure of at least 2200 Kcalories per week. During physical exercise the risk of sudden death is increased, however the net effec...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Gohlke H

    更新日期:1995-01-01 00:00:00