Abstract：
INTRODUCTION:Several approaches have been tried for the treatment of tinnitus, from cognitive-behavioral therapies and sound enrichment to medication. In this context, antioxidants, widely used in numerous areas of medicine, appear to represent a promising approach for the control of this symptom, which often is poorly controlled. OBJECTIVE:To evaluate the effects of antioxidant therapy for tinnitus in a group of elderly patients. METHODS:Prospective, randomized, double-blinded, placebo-controlled clinical trial. The sample consisted of 58 subjects aged 60 years or older, with a complaint of tinnitus associated with sensorineural hearing loss. These individuals completed the Tinnitus Handicap Inventory (THI) questionnaire before and after six months of therapy. The treatment regimens were: Ginkgo biloba dry extract (120mg/day), α-lipoic acid (60mg/day)+vitamin C (600mg/day), papaverine hydrochloride (100mg/day)+vitamin E (400mg/day), and placebo. RESULTS:There was no statistically significant difference between THI by degree (p=0.441) and by score (p=0.848) before and after treatment. CONCLUSION:There was no benefit from the use of antioxidant agents for tinnitus in this sample.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Polanski JF,Soares AD,de Mendonça Cruz OLdoi
10.1016/j.bjorl.2015.04.016subject
Has Abstractpub_date
2016-05-01 00:00:00pages
269-74issue
3eissn
1808-8694issn
1808-8686pii
S1808-8694(15)00180-9journal_volume
82pub_type
杂志文章,随机对照试验abstract：UNLABELLED:In the last decades, medical care has been increasingly permeated by the concept of evidence-based-medicine, in which clinical research plays a crucial role in establishing diagnostic and treatment. Following the improvements in clinical research, we have a growing concern and understanding that some ethical...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1590/s1808-86942011000200018
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:Perceptual evaluation is considered the gold standard to evaluate speech nasality. Several procedures are used to collect and analyze perceptual data, which makes it susceptible to errors. Therefore, there has been an increasing desire to find methods that can improve the assessment. OBJECTIVE:To describe...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2015.05.017
更新日期：2016-05-01 00:00:00
abstract：UNLABELLED:Parkinson's disease affects the central nervous system resulting in voice quality alterations. It is typically resistant to drug therapy and often persists despite extensive behavioural speech and language therapy. Previous findings show that masking noise will produce a consistent increase in voice intensit...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30129-4
更新日期：2007-09-01 00:00:00
abstract：UNLABELLED:Upper respiratory tract infections are the most common causes of medical visits in children and adults, demanding massive use of antibiotics. Bacterial resistance caused by beta-lactamase is one of the most serious problems in this matter. Sultamicillin, a double pro-drug of Ampicillin/Sulbactan, is a potent...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/s1808-8694(15)30041-0
更新日期：2006-01-01 00:00:00
abstract：UNLABELLED:Halitosis is an embarrassing symptom with a significant social impact. Halitosis affects millions of people worldwide and many resources are spent annually in products to improve halitus, unsuccessfully. The study of halitosis in a scientific basis is justified once halitosis causes social restriction, decre...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1016/S1808-8694(15)31180-0
更新日期：2007-11-01 00:00:00
abstract：INTRODUCTION:Auditory steady-state responses (ASSR) are an important tool to detect objectively frequency-specific hearing thresholds. Pure-tone audiometry is the gold-standard for hearing evaluation, although sometimes it may be inconclusive, especially in children and uncooperative adults. AIM:Compare pure tone thre...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.5935/1808-8694.20140009
更新日期：2014-01-01 00:00:00
abstract：UNLABELLED:The development of hearing aid (HA) software programming does not replace the analysis of real ears with probe microphones. AIM:To compare simulated insertion gain in HA software programming and real ear insertion gain. METHOD:A prospective study of 62 patients (aged from 29 to 93 years; 30 male and 32 fem...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1590/s1808-86942011000500003
更新日期：2011-09-01 00:00:00
abstract：UNLABELLED:Vitiligo is a skin disease characterized by absence of melanin due to melanocytes destruction. AIM:to study the incidence of hearing alterations in patients with vitiligo. METHOD:prospective audiological evaluation, transient-evoked otoacoustic emission recordings and study the effects of suppression in 24...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30841-7
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:The Montgomery T-tube is a device used as a combined tracheal stent and tracheostomy tube to prevent post-operative tracheal stenosis. OBJECTIVES:The purpose of this retrospective study is to evaluate the outcome following Montgomery T-tube stenting performed in for neck and airway injury in patients with...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2020.06.009
更新日期：2020-07-27 00:00:00
abstract：UNLABELLED:Benign Paroxysmal Positional Vertigo (BPPV) is one of the most common causes of dizziness; it constitutes the most common vestibular disorder in the elderly with vertigo. Its characteristic clinical aspect is dizziness at head movement, with not hearing alteration. AIM:This paper aims at studying the audiol...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30794-1
更新日期：2009-03-01 00:00:00
abstract：UNLABELLED:Hearing impairment (HI) is characterized by unilateral hearing loss in one ear and can result in learning difficulties, language impairment and socio-emotional difficulties. To assess the perception of hearing handicap in adult subjects, patients with unilateral sensorineural HI, non-users of individual hear...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：INTRODUCTION:Abused children and adolescents are exposed to factors that can trigger vocal changes. OBJECTIVE:This study aimed to analyze the prevalence of vocal changes in abused children and adolescents, through auditory-perceptual analysis of voice and the study of the association between vocal changes, communicati...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.11.006
更新日期：2015-01-01 00:00:00
abstract：UNLABELLED:Graves's disease is the most common cause of hyperthyroidism. There are three current therapeutic options: anti-thyroid medication, surgery, and radioactive iodine (I 131). There are few data in the literature regarding the effects of radioiodine therapy on the larynx and voice. The aim and the AIM:os this ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)31092-2
更新日期：2008-03-01 00:00:00
abstract：UNLABELLED:Cognitive and emotional factors may affect balance; psychiatric conditions are a common component in patient dizziness. The treatment of patients with vertigo may be affected to a greater degree by the suffering due to this disease than by the severity of organic changes. OBJECTIVE:This study aimed to inves...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1590/s1808-86942012000100010
更新日期：2012-02-01 00:00:00
abstract：INTRODUCTION:Educators dealing with 0-6 years old children must be individuals who are willing to take all kind of measures in order to ensure the safety of children in educational institutions and playgrounds, providing protection from diseases, and who are able to apply first aid measures in case of an accident. OBJ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2015.06.005
更新日期：2016-07-01 00:00:00
abstract：UNLABELLED:Auditory evoked brainstem responses (ABR) is a non-invasive electrical potential registration which evaluates the auditory tract from the middle ear to the auditory cortex in the first 12 milliseconds (ms). The ABR is an important otoneurological evaluation. AIM:Confirm the test's usefulness, major incidenc...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30601-7
更新日期：2008-07-01 00:00:00
abstract：INTRODUCTION:Newborn hearing screening (NHS) programs are implemented across the globe to detect early hearing impairment. In order to meet this objective, the quality of these programs should be monitored using internationally recognized indicators. OBJECTIVE:To evaluate a newborn hearing screening service (NHSS) usi...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.08.008
更新日期：2015-05-01 00:00:00
abstract：UNLABELLED:The ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM:This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN:A clinical and experimental study. METHODS:A 0...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1590/s1808-86942011000200008
更新日期：2011-03-01 00:00:00
abstract：UNLABELLED:Hearing represents the main source for acquisition of language and speaking skills in childhood. In the first months of life, the hearing impaired child is deprived of sound stimulation in the most important period of development, and consequently, might present emotional, social and linguistic disorders. Th...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30031-8
更新日期：2006-01-01 00:00:00
abstract：UNLABELLED:Laryngeal microsurgery is a kind of treatment for various laryngeal diseases. Because of the need of long instruments and delicate maneuvers, involuntary movements represent relevant difficulty and may be responsible for unintended post-operative results. AIM:This study proposes a new stabilization system, ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:Methicillin-resistant staphylococcus aureus is an emerging problem for the treatment of chronic suppurative otitis media, and also for pediatric tympanostomy tube otorrhea. To date, there are no effective topical antibiotic drugs to treat methicillin-resistant staphylococcus aureus otorrhea. OBJECTIVE:In ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2017.05.002
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Serum level of high-mobility group box 1 protein is reportedly correlated with the severity of obstructive sleep apnea. OBJECTIVE:We tried to evaluate the possibility of using the serum high-mobility group box 1 protein level as a biologic marker in obstructive sleep apnea patients. METHODS:We generated ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2020.11.019
更新日期：2021-01-02 00:00:00
abstract：UNLABELLED:Hyperbaric oxygen therapy (HBOT) has enhanced the prevention and treatment of auditory ailments such as ototoxicity. OBJECTIVE:To study the effects of HBOT upon ototoxic injuries produced by amikacin. METHOD:This experimental study included 12 albino guinea pigs, whose auditory function was assessed throug...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.5935/1808-8694.20130060
更新日期：2013-05-01 00:00:00
abstract：UNLABELLED:To identify the grade and evolution of dysphagia and dysphonia in patients undergoing supracricoid laringectomy, and to study the association of these findings with clinical and surgical variables. METHOD:The study included 22 cases undergoing supracricoid laringectomy at the Head and Neck Surgery and Otola...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)31059-4
更新日期：2007-03-01 00:00:00
abstract：INTRODUCTION:Cartilage is the grafting material of choice for certain disorders of the middle ear. The indications for its routine use remain controversial due to the possible detrimental effect on post-operative hearing. OBJECTIVE:The present study was carried out to report a personal experience with "tragal cartilag...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2018.12.006
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:There is a strong association between vertigo and migraine. Vestibular migraine (VM) was described in 1999, and diagnostic criteria were proposed in 2001 and revised in 2012. OBJECTIVE:To compare the diagnostic criteria for VM proposed in 2001 with 2012 criteria with respect to their diagnostic power and ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2015.07.007
更新日期：2015-09-01 00:00:00
abstract：INTRODUCTION:Ototoxicity refers to cellular damage or function impairment developing in the inner ear in association with any therapeutic agent or chemical substance, and still represents the principal side-effect restricting the use of cisplatin. OBJECTIVE:The aim of this study was to perform a biochemical, functiona...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2018.07.007
更新日期：2019-01-01 00:00:00
abstract：INTRODUCTION:Leiomyosarcoma is a tumor which is rarely seen in the thyroid gland. The diagnosis may be difficult and the treatment is controversial. OBJECTIVE:The objective of the study is to review the literature about a rare malignant disease of the thyroid gland which has high mortality. METHODS:Two cases of thyro...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.bjorl.2015.11.020
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:Binaurally evoked auditory evoked potentials have good diagnostic values when testing subjects with central auditory deficits. The literature on speech-evoked auditory brainstem response evoked by binaural stimulation is in fact limited. Gender disparities in speech-evoked auditory brainstem response resul...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2018.04.005
更新日期：2019-01-01 00:00:00
abstract：UNLABELLED:To setup an experimental model is the first step to study neural regeneration. AIM:Setting up an experimental model on facial nerve regeneration. MATERIAL AND METHODS:Wistar rats with complete sectioning and suturing of the extratemporal facial nerve trunk; with a behavioral and histological analysis for 9...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
