Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer.

abstract：:Intra-erythrocytic Plasmodium species can be stained with the DNA binding dye, Hoechst 33342, and the distribution of DNA content determined for parasite populations by flow cytometric measurement of fluorescence. Analysis of this distribution will determine the parasitaemia (percentage of erythrocytes infected), and ...

journal_title：Cell proliferation

authors： Jacobberger JW,Horan PK,Hare JD

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVES:The use of platelets and platelet products has become increasingly popular clinically as a means of accelerating endosseous wound healing. It is likely that growth factors released by activated platelets at the site of injury play a role in periodontal regeneration by regulating cellular activity. The purpos...

journal_title：Cell proliferation

authors： Han J,Meng HX,Tang JM,Li SL,Tang Y,Chen ZB

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:MicroRNAs are powerful regulators in hepatocellular carcinoma (HCC) tumorigenesis. MicoRNA-191 (miR-191) has been reported to play an important role in HCC, However, the regulatory mechanism is still unclear. In this study, we investigated the role of miR-191 in HCC and studied its underlying mechanisms of a...

journal_title：Cell proliferation

authors： Tian F,Yu C,Wu M,Wu X,Wan L,Zhu X

更新日期：2019-09-01 00:00:00

abstract：:This study focuses on analysis of in vitro cultures of chondrocytes from ovine articular cartilage. Isolated cells were seeded in Petri dishes, then expanded to confluence and phenotypically characterized by flow cytometry. The sigmoidal temporal profile of total counts was obtained by classic haemocytometry and corre...

journal_title：Cell proliferation

authors： Mancuso L,Liuzzo MI,Fadda S,Pisu M,Cincotti A,Arras M,La Nasa G,Concas A,Cao G

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:This study has aimed to study different culture systems that might stimulate an increase in cell proliferation of normal and osteoarthritis chondrocytes from articular cartilage in rat model. MATERIAL AND METHODS:Three culture systems using chondrocytes embedded in alginate beads were tested: chondrocytes cu...

journal_title：Cell proliferation

authors： Gomez-Camarillo MA,Almonte-Becerril M,Vasquez Tort M,Tapia-Ramirez J,Kouri Flores JB

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:SAV1 is a human homologue of Salvador that contains two protein-protein interaction modules known as WW domains and acts as a scaffolding protein. SAV1 participates in the development of diverse types of cancer. We aimed to investigate the role of SAV1 in human colorectal cancer. MATERIALS AND METHODS:Human...

journal_title：Cell proliferation

authors： Jiang J,Chang W,Fu Y,Gao Y,Zhao C,Zhang X,Zhang S

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Erythropoietin has been shown to have a protective effect in certain models of ischaemia-reperfusion, and in some cases the protection has been correlated with activation of signalling pathways known to play a role in cell survival and proliferation. We have studied whether erythropoietin would overcome direc...

journal_title：Cell proliferation

authors： Andreucci M,Fuiano G,Presta P,Lucisano G,Leone F,Fuiano L,Bisesti V,Esposito P,Russo D,Memoli B,Faga T,Michael A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Curcumin (capable of inhibiting angiogenic growth of human umbilical vein endothelial cells [HUVECs]), can be employed in vitro as a model of pathogenesis of corneal neovascularization (CRNV). The aim of this study was to explore regulatory mechanisms of microRNA (miR) levels after curcumin treatment. MATERI...

journal_title：Cell proliferation

authors： Bai Y,Wang W,Sun G,Zhang M,Dong J

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:The aim of the current study was to investigate whether nicotine treatment would induce the proliferation of isolated rat primary pancreatic acinar cells in culture by activating mitogen-activated protein kinase (MAPK) signalling and exocrine secretion. MATERIALS AND METHODS:A nicotine dose- and time-respon...

journal_title：Cell proliferation

authors： Chowdhury P,Bose C,Udupa KB

更新日期：2007-02-01 00:00:00

abstract：:The validity of the use of the monoclonal antibodies Ki-67 and anti-BrdUrd to evaluate proliferative activity of human prostate tumour models was studied. Growth of the transplantable PC-82 and PC-EW prostate tumours, as assessed by tumour volume measurements, was significantly correlated with the proliferative activi...

journal_title：Cell proliferation

authors： van Weerden WM,Moerings EP,van Kreuningen A,de Jong FH,van Steenbrugge GJ,Schröder FH

更新日期：1993-01-01 00:00:00

abstract：:Atherosclerosis is an inflammatory-fibroproliferative response of the arterial wall involving a complex set of interconnected events where cell proliferation (lymphomonocytes, and endothelial and smooth-muscle cells) and substantial perturbations of intracellular cholesterol metabolism are considered to be among the m...

journal_title：Cell proliferation

authors： Batetta B,Bonatesta RR,Sanna F,Putzolu M,Mulas MF,Collu M,Dessì S

更新日期：2002-06-01 00:00:00

abstract：:The relationship of cyclin-dependent kinase inhibitor 3 (CDKN3) with tumours has previously been presented in a number of publications. However, the molecular network and interpretation of CDKN3 through the cell cycle between non-malignancy associated hepatitis/cirrhosis and hepatocellular carcinoma (HCC) have remaine...

journal_title：Cell proliferation

authors： Wang L,Sun L,Huang J,Jiang M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:Curcumin, a natural compound, is a potent anti-cancer agent, which inhibits cell division and/or induces cell death. It is believed that normal cells are less sensitive to curcumin than malignant cells; however, the mechanism(s) responsible for curcumin's effect on normal cells are poorly understood. The aim...

journal_title：Cell proliferation

authors： Bielak-Zmijewska A,Sikora-Polaczek M,Nieznanski K,Mosieniak G,Kolano A,Maleszewski M,Styrna J,Sikora E

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:Fibrotic cataract, including posterior capsule opacification (PCO) and anterior subcapsular cataract (ASC), renders millions of people visually impaired worldwide. However, the underlying mechanism remains poorly understood. Here, we report a miRNA-based regulatory pathway that controls pathological fibrosis...

journal_title：Cell proliferation

authors： Wang X,Wang L,Sun Y,Chen B,Xiong L,Chen J,Huang M,Wu J,Tan X,Zheng Y,Huang S,Liu Y

更新日期：2020-11-01 00:00:00

abstract：:Advances in transcriptome sequencing have revealed that the genome fraction largely encodes for thousands of non-coding RNAs. Long non-coding RNAs (lncRNAs), which are a class of non-protein-coding RNAs longer than approximately 200 nucleotides in length, are emerging as key epigenetic regulators of gene expression re...

journal_title：Cell proliferation

authors： Tang L,Liang Y,Xie H,Yang X,Zheng G

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Histone deacetylase (HDAC) is an important therapeutic target in cancer. Two of the main anticancer mechanisms of HDAC inhibitors are induction of terminal differentiation and inhibition of cell proliferation. To investigate the role of HDAC in maintenance of self-renewal and cell proliferation, we treated m...

journal_title：Cell proliferation

authors： Lee S,Park JR,Seo MS,Roh KH,Park SB,Hwang JW,Sun B,Seo K,Lee YS,Kang SK,Jung JW,Kang KS

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:In peripheral neuropathy, the underlying mechanisms of nerve and muscle degeneration include chronic inflammation and oxidative stress in fibrotic tissues. (-)-Epigallocatechin gallate (EGCG) is a major, active component in green tea and may scavenge free radical oxygen and attenuate inflammation. Conservati...

journal_title：Cell proliferation

authors： Qian Y,Yao Z,Wang X,Cheng Y,Fang Z,Yuan WE,Fan C,Ouyang Y

更新日期：2020-01-01 00:00:00

abstract：:Studies on growth regulation in vitro to a large extent rely on comparison of growth curves. However, these do not discriminate between the relative contributions of the mitotic rate and the apoptotic rate to the net growth rate. In the present study, differential effects of 17beta-oestradiol (E2, 10(-8) M) and/or tam...

journal_title：Cell proliferation

authors： Budtz PE

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:Temozolomide (TMZ) is one of the most commonly used clinical drugs for glioblastoma (GBM) treatment, but its drug sensitivity needs to be improved. Gamabufotalin (CS-6), the primary component of the traditional Chinese medicine "ChanSu," was shown to have strong anti-cancer activity. However, more efforts sh...

journal_title：Cell proliferation

authors： Lan YL,Chen C,Wang X,Lou JC,Xing JS,Zou S,Hu JL,Lyu W,Zhang B

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Hyperinsulinemia is a risk factor for pancreatic cancer, but the function of insulin in carcinogenesis is unclear, so this study aimed to elucidate the carcinogenic effects of insulin and the synergistic effect with the KRAS mutation in the early stage of pancreatic cancer. MATERIALS AND METHODS:A pair of i...

journal_title：Cell proliferation

authors： Wang G,Yin L,Peng Y,Gao Y,Gao H,Zhang J,Lv N,Miao Y,Lu Z

更新日期：2019-05-01 00:00:00

abstract：:Laminin-2 (LN-2, alpha2beta1gamma1) is a basement membrane-associated laminin isoform usually considered in the context of muscle and nerve tissues. To test the hypothesis that LN-2 can additionally modulate epithelial cell biology, an analysis of the role of LN-2 in cell adhesion, activation of signalling intermediat...

journal_title：Cell proliferation

authors： Dowgiert J,Sosne G,Kurpakus-Wheater M

更新日期：2004-04-01 00:00:00

abstract：:Natural compounds derived from plant sources are well characterized as possessing a wide variety of remarkable anti-tumour properties, for example modulating programmed cell death, primarily referring to apoptosis, and autophagy. Distinct from apoptosis, autophagy (an evolutionarily conserved, multi-step lysosomal deg...

journal_title：Cell proliferation

authors： Zhang X,Chen LX,Ouyang L,Cheng Y,Liu B

更新日期：2012-10-01 00:00:00

abstract：:The microenvironmental changes in the bone marrow, spleen and liver during progression of the transplantable promyelocytic leukaemia in the Brown Norwegian rat (BNML) have been studied. We used flow cytometry to estimate cellular hypoxia and proliferation based on in vivo pulse-labelling with a mixture of 2-nitroimida...

journal_title：Cell proliferation

authors： Jensen PO,Mortensen BT,Hodgkiss RJ,Iversen PO,Christensen IJ,Helledie N,Larsen JK

更新日期：2000-12-01 00:00:00

abstract：:A number of techniques, including autoradiography after in vivo administration of tritiated thymidine ([3H]dT), immunohistochemistry after in vivo administration of bromodeoxyuridine (BrdUrd), and flow cytometry (FCM) with and without BrdUrd detection were compared in the epithelium of ventral mouse tongue. Investigat...

journal_title：Cell proliferation

authors： Dörr W,Arui J,Beisker W,Schultz-Hector S

更新日期：1994-06-01 00:00:00

abstract：:Proliferation and multidrug resistance status are key predictors of therapeutic outcome in acute myeloid leukaemia (AML). Anthracyclines such as daunorubicin (DNR) are typically used to treat AML and can induce drug resistance. The goal of the studies described here was to select a combination of fluorescent probes th...

journal_title：Cell proliferation

authors： Boutonnat J,Barbier M,Muirhead K,Mousseau M,Ronot X,Seigneurin D

更新日期：1999-08-01 00:00:00

abstract：:The human promyelocytic leukaemia cell line, HL-60, was investigated with regard to proliferation and terminal differentiation following irradiation. The cells were X-irradiated and induced with 1.25% dimethyl sulfoxide (DMSO) towards the granulocytic lineage. Proliferation was measured via cell growth, clonogenicity ...

journal_title：Cell proliferation

authors： Sendler A,Kaffenberger W,Nuyken I,van Beuningen D

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVES:Cancer stem cells (CSCs) compose a subpopulation of cells within a tumour that can self-renew and proliferate. Growth factors such as epidermal growth factor (EGF) and basic fibroblast growth factor (b-FGF) promote cancer stem cell proliferation in many solid tumours. This study assesses whether EGF, bFGF an...

journal_title：Cell proliferation

authors： Feng Y,Dai X,Li X,Wang H,Liu J,Zhang J,Du Y,Xia L

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:Mesenchymal stem cells (MSCs) are frequently used for bone regeneration, however, they are limited in quantity. Moreover, their proliferation and differentiation capabilities reduce during cell culture expansion. Potential application of induced pluripotent stem cells (iPSCs) has been reported as a promising...

journal_title：Cell proliferation

authors： Bastami F,Nazeman P,Moslemi H,Rezai Rad M,Sharifi K,Khojasteh A

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:miRNAs play crucial roles in human tumourigenesis. This study was performed to measure expression and function of miR-762 in breast cancer. MATERIALS AND METHODS:Expression of miR-762 in breast tissues and cell lines (SK-BR-3, DA-MB-435s, MCF-7 and MDA-MB-231, HBL-100) was measured by using real-time RT-PCR...

journal_title：Cell proliferation

authors： Li Y,Huang R,Wang L,Hao J,Zhang Q,Ling R,Yun J

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:Cardiac atrial appendage stem cells (CASCs) have recently emerged as an attractive candidate for cardiac regeneration after myocardial infarction. As with other cardiac stem cells, CASCs have to be expanded ex vivo to obtain clinically relevant cell numbers. However, foetal calf serum (FCS), which is routine...

journal_title：Cell proliferation

authors： Windmolders S,Willems L,Daniëls A,Linsen L,Fanton Y,Hendrikx M,Koninckx R,Rummens JL,Hensen K

更新日期：2015-04-01 00:00:00