Abstract:
:Perifused anterior hemipituitaries from one male and 4 female monkeys released GH and PRL in a pulsatile pattern, with mean +/- SE interpulse intervals of 8.2 +/- 0.4 and 8.5 +/- 0.3 min, as determined by a cycle detection computer algorithm. Mean hormone concentrations in the perifusate fractions collected at 2-min intervals were 435 +/- 89 (GH) and 515 +/- 262 (PRL) ng/ml. Pulse amplitudes averaged 74 +/- 16 ng/ml for GH and 189 +/- 89 ng/ml for PRL. These findings suggest the presence of a high frequency pulsatile secretory mechanism within the primate pituitary.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Stewart JK,Clifton DK,Koerker DJ,Rogol AD,Jaffe T,Goodner CJdoi
10.1210/endo-116-1-1subject
Has Abstractpub_date
1985-01-01 00:00:00pages
1-5issue
1eissn
0013-7227issn
1945-7170journal_volume
116pub_type
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