Abstract：
PURPOSE:This study aimed to investigate longitudinal associations of objectively measured physical activity (PA) and sedentary behavior (SB) with body composition and physical fitness at a 12-month follow-up in healthy Swedish 4-yr-old children. METHODS:The data from the population-based MINISTOP trial were collected between 2014 and 2016, and this study included the 138 children who were in the control group. PA and SB were assessed using the wrist-worn ActiGraph (wGT3x-BT) accelerometer during seven 24-h periods and, subsequently, defined as SB, light-intensity PA, moderate-intensity PA, vigorous-intensity PA (VPA), and moderate-to-vigorous PA (MVPA). Body composition was measured using air-displacement plethysmography and physical fitness (cardiorespiratory fitness, lower and upper muscular strength as well as motor fitness) by the PREFIT fitness battery. Linear regression and isotemporal substitution models were applied. RESULTS:Greater VPA and MVPA at the age of 4.5 yr were associated with higher fat-free mass index (FFMI) at 5.5 yr (P < 0.001 and P = 0.044, respectively). Furthermore, greater VPA and MVPA at the age of 4.5 yr were associated with higher scores for cardiorespiratory fitness, lower body muscular strength, and motor fitness at 12-month follow-up (P = 0.001 to P = 0.031). Substituting 5 min·d of SB, light-intensity PA, or moderate-intensity PA for VPA at the age of 4.5 yr were associated with higher FFMI, and with greater upper and lower muscular strength at 12-month follow-up (P < 0.001 to P = 0.046). CONCLUSION:Higher VPA and MVPA at the age of 4.5 yr were significantly associated with higher FFMI and better physical fitness at 12-month follow-up. Our results indicate that promoting high-intensity PA at young ages may have long-term beneficial effects on childhood body composition and physical fitness, in particular muscular strength.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Leppänen MH,Henriksson P,Delisle Nyström C,Henriksson H,Ortega FB,Pomeroy J,Ruiz JR,Cadenas-Sanchez C,Löf Mdoi
10.1249/MSS.0000000000001313subject
Has Abstractpub_date
2017-10-01 00:00:00pages
2078-2085issue
10eissn
0195-9131issn
1530-0315journal_volume
49pub_type
杂志文章abstract：:The physiological mechanism of exercise-induced hyperfibrinolysis is not fully understood. It has been reported that exercise increases plasma arginine vasopressin (PAVP) and that PAVP infusion enhances blood fibrinolytic activity (FA). To characterize the fibrinolytic role of PAVP during exercise, PAVP and FA were ex...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-08-01 00:00:00
abstract：PURPOSE:The objective of this study is to determine whether individuals with type 1 diabetes exhibit impairments in local and whole-body heat loss responses that could affect core temperature regulation during exercise in the heat compared with matched, nondiabetic individuals. METHODS:Twelve otherwise healthy individ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31829002f3
更新日期：2013-09-01 00:00:00
abstract：PURPOSE:Muscle injury is the most common sports injury. Muscle stiffness, a risk factor for muscle injury, is lower in females than in males, implying that sex-related genetic polymorphisms influence muscle injury associated with muscle stiffness. The present study aimed to clarify the associations between two genetic ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001750
更新日期：2019-01-01 00:00:00
abstract：:The association between increasing age and decreasing vagal modulation is well known. However, the importance of fitness as a determinant of the decline in vagal modulation with age is not established. To test the hypothesis that decreasing vagal modulation is largely a function of declining fitness rather than increa...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199706000-00012
更新日期：1997-06-01 00:00:00
abstract：PURPOSE:It is unclear how muscle strength in tibial rotation and knee abduction change following anterior cruciate ligament (ACL) injury and reconstruction. Such strength changes are likely, considering the oblique orientation of the ACL and the constraint provided by the ACL at various tibial rotation and adduction po...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-200201000-00002
更新日期：2002-01-01 00:00:00
abstract：PURPOSE:The objectives of this study were 1) to examine the differences between a noninjured (C) cohort of runners (N = 70) and runners afflicted with anterior knee pain (AKP) according to selected training, anthropometric, rearfoot motion, ground reaction force, and muscular strength and endurance variables; 2) to exp...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200011000-00003
更新日期：2000-11-01 00:00:00
abstract：INTRODUCTION:Acute bupropion (dopamine/noradrenaline reuptake inhibitor) administration significantly improved time trial performance and increased core temperature in the heat (30 degrees C). PURPOSE:The present study was performed to examine the effect of a dopaminergic reuptake inhibitor on exercise capacity and th...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e3181659c4d
更新日期：2008-05-01 00:00:00
abstract：:The ventilatory stimulating effects of hypoxia occurring at carotid bodies are potentiated by exercise. However, hypoxia also has central ventilatory depressive effects; the potential interactions between this hypoxic depression and exercise have not been studied. We examined the ventilatory response to a 20 min perio...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:Endurance exercise training increases fat oxidation during large muscle mass exercise. Although the source of this fat has been thought to be plasma free fatty acids (FFA) released from adipose tissue, the training-induced decrease in lipolytic hormonal responses to exercise is not consistent with this concept. The pu...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199705000-00008
更新日期：1997-05-01 00:00:00
abstract：:Potential physiological, anthropometric, and training determinants of running economy (RE) were studied in a heterogeneous group of habitual distance runners (N = 188, 119 males, 69 females). RE was measured as VO2 (ml.kg-1.min-1) during level treadmill running at 161 m.min-1 (6 mph) (VO2-6). Examined as potential det...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：BACKGROUND:Pedometry methods for collecting data in young populations are advancing, but it is unclear how many days of data are enough for population monitoring. METHODS:Using random-digit dialing, 11,669 5- to 19-yr-olds were recruited into the Canadian Physical Activity Levels among Youth study and mailed a data co...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181b67544
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:This is a case study of an aerobically trained, multisport, female athlete (age = 39) diagnosed with stage IIIc human epidermal growth factor receptor 2 positive breast cancer. The focus of the study is on measures of cardiorespiratory fitness (V˙O2peak) through the course of cancer therapy. METHODS:A symptom-...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000987
更新日期：2016-10-01 00:00:00
abstract：:Throughout a beat swinging motion prior to a kip the gymnast changes the relative orientation of his legs and head-torso with respect to his arms. It was observed that if these changes occurred in a correct order he could rapidly increase his swing with his limited strength. If changes in orientation of the body parts...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1980-04-01 00:00:00
abstract：PURPOSE:The purpose of this investigation was to examine the effects of differing amounts of beta-hydroxy-beta-methylbutyrate (HMB), 0, 36, and 76 mg x kg(-1) x d(-1), on hematology, hepatic and renal function during 8 wk of resistance training. METHODS:Thirty-seven, untrained collegiate males and were randomly assign...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005768-200012000-00023
更新日期：2000-12-01 00:00:00
abstract：PURPOSE:Endurance training improves skeletal muscular function including energy metabolism and structure. Sex steroid hormones partly contribute to the exercise-induced muscular adaptations. Recently, we demonstrated that skeletal muscle contains steroidogenic converting enzymes to synthesize sex steroid hormones and a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31821e9d74
更新日期：2011-11-01 00:00:00
abstract：INTRODUCTION:The development of chronic ankle instability (CAI) is the primary residual deficit after ankle joint sprain. It has been proposed that CAI is characterized by two entities, namely, mechanical instability and functional instability. Each of these entities in turn is composed of various insufficiencies. Rese...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/MSS.0b013e3181de7a8a
更新日期：2010-11-01 00:00:00
abstract：:The effect of physical exercise and vitamin C on iron absorption after oral iron administration was investigated. Eight healthy male subjects without iron deficiency were studied after administration of 100 mg ferric sodium citrate complex, 100 mg ferric sodium citrate complex with 200 mg ascorbic acid, and without ir...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1097/00005768-199612000-00005
更新日期：1996-12-01 00:00:00
abstract：PURPOSE:Water polo is a sport involving extremely intense exercise training that might be expected to result in major cardiac adaptations. The purpose of our study was to evaluate cardiac size, determine VO(2max) of top-level water polo players, and compare the findings with those of other top-level athletes. METHODS:...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000152805.34215.97
更新日期：2005-02-01 00:00:00
abstract：PURPOSE:This study aimed to establish whether time spent in sport-related physical activities and sedentary behaviors (e.g., TV viewing, videogame usage, and homework) was prospectively associated with change in blood pressure (BP) for 5 yr. METHODS:Eight hundred and twenty-one students age 6 yr at baseline (397 girls...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000166
更新日期：2014-04-01 00:00:00
abstract：:The influence of anthropometry and body composition on running economy is unclear, with previous investigations involving small relatively homogeneous groups of runners and limited anthropometric/composition measurements. PURPOSE:To comprehensively investigate the relationships of anthropometry and body composition w...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002158
更新日期：2020-03-01 00:00:00
abstract：:This study examined the effects of age and physical activity on body composition and fat distribution by comparing differences between young and older endurance trained men and women with differences between young and older sedentary people. Although indices of total body adiposity (fat mass, percent body fat) were hi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：PURPOSE:The increased physiological demand of pregnancy results in profound adaptation of the maternal cardiovascular system, reflected by greater resting cardiac output and left ventricular (LV) deformation. Whether the increased resting demand alters acute cardiac responses to exercise in healthy pregnant women is no...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002554
更新日期：2020-11-03 00:00:00
abstract：PURPOSE:Exercise training restores innate immune system cell function in post-myocardial infarction (post-MI) rats. However, studies of the involvement of lymphocyte (Ly) in the setting of the congestive heart failure (CHF) are few. To address this issue, we investigated the function of Ly obtained from cervical lymph ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31815ed6d2
更新日期：2008-03-01 00:00:00
abstract：:Young children's regular participation in physical activity is important not only to prevent excess weight gain and avoid chronic health problems but also to promote optimal physical, social, and psychological development. Given the large number of children enrolled in some form of out-of-home child care, this setting...
journal_title：Medicine and science in sports and exercise
pub_type：
doi：10.1249/MSS.0b013e3181ce9f85
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:To compare the total exercise loads (intensity x volume) of the Vuelta a España and Tour de France during the last year. METHODS:Seven professional road cyclists (28 +/- 1 yr; [OV0312]O(2max): 74.6 +/- 2.2 mL.kg-1.min-1) who participated in both Tour and Vuelta during the years 1997, 1999, 2000, or 2001 were c...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000064999.82036.B4
更新日期：2003-05-01 00:00:00
abstract：:The purpose was to study the effects of skipping rate on energy expenditure and sex differences in response to rope skipping. Responses of 19 males and 11 females were measured while skipping for 5 min at 125, 135 and 145 skips . min-1. Expired air was routed through a hollow handle to collection bags to provide unint...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：UNLABELLED:Considerable evidence suggests regular physical activity can reduce chronic pain symptoms. The dysfunction of endogenous facilitatory and inhibitory systems has been implicated in multiple chronic pain conditions. However, few studies have investigated the relationship between levels of physical activity and...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3182a69cf1
更新日期：2014-03-01 00:00:00
abstract：PURPOSE:To determine whether physical activity and fitness change in girls with and without a predisposition to obesity from 8 to 10 yr of age. METHODS:Normal-weight girls (N = 91) were recruited at 8 yr of age according to parental body mass index (BMI): LN = girls with two lean (BMI < 25 kg.m-2) parents, LNOB = girl...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000113666.98463.B0
更新日期：2004-02-01 00:00:00
abstract：:MRI is an excellent noninvasive method of diagnosing difficult shoulder problems. Although usually not needed for classic primary impingement syndrome or clinically obvious rotator cuff tears, MRI may be helpful in diagnosing secondary causes of impingement or in some cases involving partial rotator cuff tears. Some s...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1097/00005768-199804001-00002
更新日期：1998-04-01 00:00:00
abstract：:The serum levels of testosterone, free testosterone, prolactin, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) were measured at rest, during 45 min of exercise on a bicycle ergometer at 50% of the subjects' previously determined maximal oxygen uptake (VO2max), and during a 30-min recovery period. Ten...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1985-02-01 00:00:00
